Ngā hua rapu - Y.N. Vashisht Gopal
- E whakaatu ana i te 1 - 15 hua o te 15
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Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <i>Braf-</i>Mutant Human Cutaneous Melanoma Cells mā Y.N. Vashisht Gopal, Wanleng Deng, Scott E. Woodman, Kakajan Komurov, Prahlad T. Ram, Paul D. Smith, Michael A. Davies
I whakaputaina 2010Artigo -
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Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications mā Grant M. Fischer, Y.N. Vashisht Gopal, Jennifer L. McQuade, Weiyi Peng, Ralph J. DeBerardinis, Michael A. Davies
I whakaputaina 2017Revisão -
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Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma mā Michael A. Davies, Katherine Stemke‐Hale, E. Lin, Carmen S. Tellez, Wanleng Deng, Y.N. Vashisht Gopal, Scott E. Woodman, Tiffany L. Calderone, Zhenlin Ju, Alexander J. Lazar, Víctor G. Prieto, Kenneth Aldape, Gordon B. Mills, Jeffrey E. Gershenwald
I whakaputaina 2009Artigo -
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Activity of dasatinib against<i>L576P KIT</i>mutant melanoma: Molecular, cellular, and clinical correlates mā Scott E. Woodman, Jonathan C. Trent, Katherine Stemke‐Hale, Alexander J. Lazar, Sabrina Pricl, Giovanni M. Pavan, Maurizio Fermeglia, Y.N. Vashisht Gopal, Dan Yang, Donald A. Podoloff, Doina Ivan, Kevin B. Kim, Nikolaos G. Papadopoulos, Patrick Hwu, Gordon B. Mills, Michael A. Davies
I whakaputaina 2009Artigo -
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The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell–Mediated Immunotherapies mā Sruthy Varghese, Snigdha Pramanik, Leila J. Williams, Hannah R. Hodges, Courtney W. Hudgens, Grant M. Fischer, Catherine K. Luo, Barbara Knighton, Lin Tan, Philip L. Lorenzi, Andrew L. MacKinnon, Jennifer L. McQuade, Yared Hailemichael, Jason Roszik, Weiyi Peng, Y.N. Vashisht Gopal
I whakaputaina 2020Artigo -
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Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target mā Guo Chen, Nitin Chakravarti, Kimberly Aardalen, Alexander J. Lazar, Michael T. Tetzlaff, Bradley Wubbenhorst, Sang-Bae Kim, Scott Kopetz, Alicia A. Ledoux, Y.N. Vashisht Gopal, Cristiano Gonçalves Pereira, Wanleng Deng, Ju–Seog Lee, Katherine L. Nathanson, Kenneth Aldape, Víctor G. Prieto, Darrin D. Stuart, Michael A. Davies
I whakaputaina 2014Artigo -
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Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents mā Muling Mao, Feng Tian, John M. Mariadason, Chun C. Tsao, Robert Lemos, Farshid Dayyani, Y.N. Vashisht Gopal, Zhi-Qin Jiang, Ignacio I. Wistuba, Xi Tang, William G. Bornman, Gideon Bollag, Gordon B. Mills, Garth Powis, Jayesh Desai, Gary E. Gallick, Michael A. Davies, Scott Kopetz
I whakaputaina 2012Artigo -
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Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma mā Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta M. Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit R. Patel, Cristiano Gonçalves Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad T. Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies
I whakaputaina 2014Artigo -
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A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma mā Y.N. Vashisht Gopal, Seth T. Gammon, Rishika Prasad, Barbara Knighton, Federica Pisaneschi, Jason Roszik, Ningping Feng, Sarah Johnson, Snigdha Pramanik, Jessica Sudderth, Dawen Sui, Courtney W. Hudgens, Grant M. Fischer, Wanleng Deng, Alexandre Reuben, Weiyi Peng, Jian Wang, Jennifer L. McQuade, Michael T. Tetzlaff, Maria Emilia Di Francesco, Joe Marszalek, David Piwnica‐Worms, Ralph J. DeBerardinis, Michael A. Davies
I whakaputaina 2019Artigo -
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Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays mā Jun Li, Wei Zhao, Rehan Akbani, Wenbin Liu, Zhenlin Ju, Shiyun Ling, Christopher P. Vellano, Paul Roebuck, Qinghua Yu, Agda Karina Eterovic, Lauren A. Byers, Michael A. Davies, Wanleng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika M. von Euw, Dennis J. Slamon, Dylan Conklin, John V. Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yiling Lu, Gordon B. Mills, Han Liang
I whakaputaina 2017Artigo -
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Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy mā Tina Cascone, Jodi A. McKenzie, Rina M. Mbofung, Simone Punt, Zhe Wang, Chunyu Xu, Leila J. Williams, Zhiqiang Wang, Christopher A. Bristow, Alessandro Carugo, Michael Peoples, Lerong Li, Tatiana V. Karpinets, Lu Huang, Shruti Malu, Caitlin Creasy, Sara Elizabeth Leahey, Jiong Chen, Yuan Chen, Helen Pelicano, Chantale Bernatchez, Y.N. Vashisht Gopal, Timothy P. Heffernan, Jianhua Hu, Jing Wang, Rodabe N. Amaria, Levi A. Garraway, Peng Huang, Peiying Yang, Ignacio I. Wistuba, Scott E. Woodman, Jason Roszik, R. Eric Davis, Michael A. Davies, John V. Heymach, Patrick Hwu, Weiyi Peng
I whakaputaina 2018Artigo -
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Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases mā Grant M. Fischer, Ali Jalali, David A. Kircher, Won‐Chul Lee, Jennifer L. McQuade, Lauren E. Haydu, Aron Y. Joon, Alexandre Reuben, Mariana Petaccia de Macêdo, Fernando C. L. Carapeto, Chendong Yang, Anuj Srivastava, Chandrashekar R. Ambati, Arun Sreekumar, Courtney W. Hudgens, Barbara Knighton, Wanleng Deng, Sherise D. Ferguson, Hussein A. Tawbi, Isabella C. Glitza, Jeffrey E. Gershenwald, Y.N. Vashisht Gopal, Patrick Hwu, Jason T. Huse, Jennifer A. Wargo, P. Andrew Futreal, Nagireddy Putluri, Alexander J. Lazar, Ralph J. DeBerardinis, Joseph R. Marszalek, Jianjun Zhang, Sheri L. Holmen, Michael T. Tetzlaff, Michael A. Davies
I whakaputaina 2019Artigo -
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Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma mā Andrew W. Hahn, Ashley V. Menk, Dayana B. Rivadeneira, Ryan C. Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K. Mishra, Tuba N. Gide, Camelia Quek, Yan Zang, Christine N. Spencer, Alexander M. Menzies, Carrie R. Daniel, Courtney W. Hudgens, Theodore S. Nowicki, Lauren E. Haydu, M.A. Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M. Burton, Jared Malke, Julie M. Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E. Woodman, Y.N. Vashisht Gopal, Renato Guerrieri, Grant M. Fischer, Jian Wang, Khalida Wani, John F. Thompson, Jeffrey E. Lee, Patrick Hwu, Nadim J. Ajami, Jeffrey E. Gershenwald, Georgina V. Long, Richard A. Scolyer, Michael T. Tetzlaff, Alexander J. Lazar, Dirk Schadendorf, Jennifer A. Wargo, John M. Kirkwood, Ralph J. DeBerardinis, Han Liang, P. Andrew Futreal, Jianhua Zhang, James S. Wilmott, Weiyi Peng, Michael A. Davies, Greg M. Delgoffe, Yana G. Najjar, Jennifer L. McQuade
I whakaputaina 2022Carta
Ngā utauta rapu:
Ngā marau whai pānga
Biology
Cancer research
Melanoma
Cancer
Genetics
Medicine
Biochemistry
Gene
PI3K/AKT/mTOR pathway
Signal transduction
Cell biology
Bioinformatics
Colorectal cancer
Immune system
Immunology
Internal medicine
Computational biology
MAPK/ERK pathway
Metabolism
Oncology
Pharmacology
Apoptosis
Biotechnology
Cell
Chemistry
Computer science
Glycolysis
In vivo
KRAS
Kinase