Torthaí cuardaigh - Y.N. Vashisht Gopal

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  1. 1
    Parthenolide Specifically Depletes Histone Deacetylase 1 Protein and Induces Cell Death through Ataxia Telangiectasia Mutated

    Parthenolide Specifically Depletes Histone Deacetylase 1 Protein and Induces Cell Death through Ataxia Telangiectasia Mutated de réir Y.N. Vashisht Gopal, Tarandeep S. Arora, Michael W. Van Dyke

    Foilsithe / Cruthaithe 2007
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  2. 2
    Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions

    Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions de réir Y.N. Vashisht Gopal, Ekkawit Chanchorn, Michael W. Van Dyke

    Foilsithe / Cruthaithe 2009
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  3. 3
    Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <i>Braf-</i>Mutant Human Cutaneous Melanoma Cells

    Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <i>Braf-</i>Mutant Human Cutaneous Melanoma Cells de réir Y.N. Vashisht Gopal, Wanleng Deng, Scott E. Woodman, Kakajan Komurov, Prahlad T. Ram, Paul D. Smith, Michael A. Davies

    Foilsithe / Cruthaithe 2010
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  4. 4
    Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

    Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications de réir Grant M. Fischer, Y.N. Vashisht Gopal, Jennifer L. McQuade, Weiyi Peng, Ralph J. DeBerardinis, Michael A. Davies

    Foilsithe / Cruthaithe 2017
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  5. 5
    Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

    Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma de réir Michael A. Davies, Katherine Stemke‐Hale, E. Lin, Carmen S. Tellez, Wanleng Deng, Y.N. Vashisht Gopal, Scott E. Woodman, Tiffany L. Calderone, Zhenlin Ju, Alexander J. Lazar, Víctor G. Prieto, Kenneth Aldape, Gordon B. Mills, Jeffrey E. Gershenwald

    Foilsithe / Cruthaithe 2009
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  6. 6
    Activity of dasatinib against<i>L576P KIT</i>mutant melanoma: Molecular, cellular, and clinical correlates

    Activity of dasatinib against<i>L576P KIT</i>mutant melanoma: Molecular, cellular, and clinical correlates de réir Scott E. Woodman, Jonathan C. Trent, Katherine Stemke‐Hale, Alexander J. Lazar, Sabrina Pricl, Giovanni M. Pavan, Maurizio Fermeglia, Y.N. Vashisht Gopal, Dan Yang, Donald A. Podoloff, Doina Ivan, Kevin B. Kim, Nikolaos G. Papadopoulos, Patrick Hwu, Gordon B. Mills, Michael A. Davies

    Foilsithe / Cruthaithe 2009
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  7. 7
    The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell–Mediated Immunotherapies

    The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell–Mediated Immunotherapies de réir Sruthy Varghese, Snigdha Pramanik, Leila J. Williams, Hannah R. Hodges, Courtney W. Hudgens, Grant M. Fischer, Catherine K. Luo, Barbara Knighton, Lin Tan, Philip L. Lorenzi, Andrew L. MacKinnon, Jennifer L. McQuade, Yared Hailemichael, Jason Roszik, Weiyi Peng, Y.N. Vashisht Gopal

    Foilsithe / Cruthaithe 2020
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  8. 8
    Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target

    Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target de réir Guo Chen, Nitin Chakravarti, Kimberly Aardalen, Alexander J. Lazar, Michael T. Tetzlaff, Bradley Wubbenhorst, Sang-Bae Kim, Scott Kopetz, Alicia A. Ledoux, Y.N. Vashisht Gopal, Cristiano Gonçalves Pereira, Wanleng Deng, Ju–Seog Lee, Katherine L. Nathanson, Kenneth Aldape, Víctor G. Prieto, Darrin D. Stuart, Michael A. Davies

    Foilsithe / Cruthaithe 2014
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  9. 9
    Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

    Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents de réir Muling Mao, Feng Tian, John M. Mariadason, Chun C. Tsao, Robert Lemos, Farshid Dayyani, Y.N. Vashisht Gopal, Zhi-Qin Jiang, Ignacio I. Wistuba, Xi Tang, William G. Bornman, Gideon Bollag, Gordon B. Mills, Garth Powis, Jayesh Desai, Gary E. Gallick, Michael A. Davies, Scott Kopetz

    Foilsithe / Cruthaithe 2012
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  10. 10
    Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma

    Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma de réir Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta M. Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit R. Patel, Cristiano Gonçalves Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad T. Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies

    Foilsithe / Cruthaithe 2014
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  11. 11
    A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma

    A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma de réir Y.N. Vashisht Gopal, Seth T. Gammon, Rishika Prasad, Barbara Knighton, Federica Pisaneschi, Jason Roszik, Ningping Feng, Sarah Johnson, Snigdha Pramanik, Jessica Sudderth, Dawen Sui, Courtney W. Hudgens, Grant M. Fischer, Wanleng Deng, Alexandre Reuben, Weiyi Peng, Jian Wang, Jennifer L. McQuade, Michael T. Tetzlaff, Maria Emilia Di Francesco, Joe Marszalek, David Piwnica‐Worms, Ralph J. DeBerardinis, Michael A. Davies

    Foilsithe / Cruthaithe 2019
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  12. 12
    Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

    Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays de réir Jun Li, Wei Zhao, Rehan Akbani, Wenbin Liu, Zhenlin Ju, Shiyun Ling, Christopher P. Vellano, Paul Roebuck, Qinghua Yu, Agda Karina Eterovic, Lauren A. Byers, Michael A. Davies, Wanleng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika M. von Euw, Dennis J. Slamon, Dylan Conklin, John V. Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yiling Lu, Gordon B. Mills, Han Liang

    Foilsithe / Cruthaithe 2017
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  13. 13
    Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

    Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy de réir Tina Cascone, Jodi A. McKenzie, Rina M. Mbofung, Simone Punt, Zhe Wang, Chunyu Xu, Leila J. Williams, Zhiqiang Wang, Christopher A. Bristow, Alessandro Carugo, Michael Peoples, Lerong Li, Tatiana V. Karpinets, Lu Huang, Shruti Malu, Caitlin Creasy, Sara Elizabeth Leahey, Jiong Chen, Yuan Chen, Helen Pelicano, Chantale Bernatchez, Y.N. Vashisht Gopal, Timothy P. Heffernan, Jianhua Hu, Jing Wang, Rodabe N. Amaria, Levi A. Garraway, Peng Huang, Peiying Yang, Ignacio I. Wistuba, Scott E. Woodman, Jason Roszik, R. Eric Davis, Michael A. Davies, John V. Heymach, Patrick Hwu, Weiyi Peng

    Foilsithe / Cruthaithe 2018
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  14. 14
    Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

    Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases de réir Grant M. Fischer, Ali Jalali, David A. Kircher, Won‐Chul Lee, Jennifer L. McQuade, Lauren E. Haydu, Aron Y. Joon, Alexandre Reuben, Mariana Petaccia de Macêdo, Fernando C. L. Carapeto, Chendong Yang, Anuj Srivastava, Chandrashekar R. Ambati, Arun Sreekumar, Courtney W. Hudgens, Barbara Knighton, Wanleng Deng, Sherise D. Ferguson, Hussein A. Tawbi, Isabella C. Glitza, Jeffrey E. Gershenwald, Y.N. Vashisht Gopal, Patrick Hwu, Jason T. Huse, Jennifer A. Wargo, P. Andrew Futreal, Nagireddy Putluri, Alexander J. Lazar, Ralph J. DeBerardinis, Joseph R. Marszalek, Jianjun Zhang, Sheri L. Holmen, Michael T. Tetzlaff, Michael A. Davies

    Foilsithe / Cruthaithe 2019
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  15. 15
    Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

    Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma de réir Andrew W. Hahn, Ashley V. Menk, Dayana B. Rivadeneira, Ryan C. Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K. Mishra, Tuba N. Gide, Camelia Quek, Yan Zang, Christine N. Spencer, Alexander M. Menzies, Carrie R. Daniel, Courtney W. Hudgens, Theodore S. Nowicki, Lauren E. Haydu, M.A. Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M. Burton, Jared Malke, Julie M. Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E. Woodman, Y.N. Vashisht Gopal, Renato Guerrieri, Grant M. Fischer, Jian Wang, Khalida Wani, John F. Thompson, Jeffrey E. Lee, Patrick Hwu, Nadim J. Ajami, Jeffrey E. Gershenwald, Georgina V. Long, Richard A. Scolyer, Michael T. Tetzlaff, Alexander J. Lazar, Dirk Schadendorf, Jennifer A. Wargo, John M. Kirkwood, Ralph J. DeBerardinis, Han Liang, P. Andrew Futreal, Jianhua Zhang, James S. Wilmott, Weiyi Peng, Michael A. Davies, Greg M. Delgoffe, Yana G. Najjar, Jennifer L. McQuade

    Foilsithe / Cruthaithe 2022
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