Canlyniadau Chwilio - Y.N. Vashisht Gopal

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  1. 1
    Parthenolide Specifically Depletes Histone Deacetylase 1 Protein and Induces Cell Death through Ataxia Telangiectasia Mutated

    Parthenolide Specifically Depletes Histone Deacetylase 1 Protein and Induces Cell Death through Ataxia Telangiectasia Mutated gan Y.N. Vashisht Gopal, Tarandeep S. Arora, Michael W. Van Dyke

    Cyhoeddwyd 2007
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  2. 2
    Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions

    Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions gan Y.N. Vashisht Gopal, Ekkawit Chanchorn, Michael W. Van Dyke

    Cyhoeddwyd 2009
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  3. 3
    Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <i>Braf-</i>Mutant Human Cutaneous Melanoma Cells

    Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <i>Braf-</i>Mutant Human Cutaneous Melanoma Cells gan Y.N. Vashisht Gopal, Wanleng Deng, Scott E. Woodman, Kakajan Komurov, Prahlad T. Ram, Paul D. Smith, Michael A. Davies

    Cyhoeddwyd 2010
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  4. 4
    Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

    Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications gan Grant M. Fischer, Y.N. Vashisht Gopal, Jennifer L. McQuade, Weiyi Peng, Ralph J. DeBerardinis, Michael A. Davies

    Cyhoeddwyd 2017
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    Revisão
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  5. 5
    Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

    Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma gan Michael A. Davies, Katherine Stemke‐Hale, E. Lin, Carmen S. Tellez, Wanleng Deng, Y.N. Vashisht Gopal, Scott E. Woodman, Tiffany L. Calderone, Zhenlin Ju, Alexander J. Lazar, Víctor G. Prieto, Kenneth Aldape, Gordon B. Mills, Jeffrey E. Gershenwald

    Cyhoeddwyd 2009
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  6. 6
    Activity of dasatinib against<i>L576P KIT</i>mutant melanoma: Molecular, cellular, and clinical correlates

    Activity of dasatinib against<i>L576P KIT</i>mutant melanoma: Molecular, cellular, and clinical correlates gan Scott E. Woodman, Jonathan C. Trent, Katherine Stemke‐Hale, Alexander J. Lazar, Sabrina Pricl, Giovanni M. Pavan, Maurizio Fermeglia, Y.N. Vashisht Gopal, Dan Yang, Donald A. Podoloff, Doina Ivan, Kevin B. Kim, Nikolaos G. Papadopoulos, Patrick Hwu, Gordon B. Mills, Michael A. Davies

    Cyhoeddwyd 2009
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  7. 7
    The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell–Mediated Immunotherapies

    The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell–Mediated Immunotherapies gan Sruthy Varghese, Snigdha Pramanik, Leila J. Williams, Hannah R. Hodges, Courtney W. Hudgens, Grant M. Fischer, Catherine K. Luo, Barbara Knighton, Lin Tan, Philip L. Lorenzi, Andrew L. MacKinnon, Jennifer L. McQuade, Yared Hailemichael, Jason Roszik, Weiyi Peng, Y.N. Vashisht Gopal

    Cyhoeddwyd 2020
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  8. 8
    Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target

    Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target gan Guo Chen, Nitin Chakravarti, Kimberly Aardalen, Alexander J. Lazar, Michael T. Tetzlaff, Bradley Wubbenhorst, Sang-Bae Kim, Scott Kopetz, Alicia A. Ledoux, Y.N. Vashisht Gopal, Cristiano Gonçalves Pereira, Wanleng Deng, Ju–Seog Lee, Katherine L. Nathanson, Kenneth Aldape, Víctor G. Prieto, Darrin D. Stuart, Michael A. Davies

    Cyhoeddwyd 2014
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  9. 9
    Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

    Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents gan Muling Mao, Feng Tian, John M. Mariadason, Chun C. Tsao, Robert Lemos, Farshid Dayyani, Y.N. Vashisht Gopal, Zhi-Qin Jiang, Ignacio I. Wistuba, Xi Tang, William G. Bornman, Gideon Bollag, Gordon B. Mills, Garth Powis, Jayesh Desai, Gary E. Gallick, Michael A. Davies, Scott Kopetz

    Cyhoeddwyd 2012
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  10. 10
    Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma

    Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma gan Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta M. Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit R. Patel, Cristiano Gonçalves Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad T. Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies

    Cyhoeddwyd 2014
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  11. 11
    A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma

    A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma gan Y.N. Vashisht Gopal, Seth T. Gammon, Rishika Prasad, Barbara Knighton, Federica Pisaneschi, Jason Roszik, Ningping Feng, Sarah Johnson, Snigdha Pramanik, Jessica Sudderth, Dawen Sui, Courtney W. Hudgens, Grant M. Fischer, Wanleng Deng, Alexandre Reuben, Weiyi Peng, Jian Wang, Jennifer L. McQuade, Michael T. Tetzlaff, Maria Emilia Di Francesco, Joe Marszalek, David Piwnica‐Worms, Ralph J. DeBerardinis, Michael A. Davies

    Cyhoeddwyd 2019
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  12. 12
    Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

    Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays gan Jun Li, Wei Zhao, Rehan Akbani, Wenbin Liu, Zhenlin Ju, Shiyun Ling, Christopher P. Vellano, Paul Roebuck, Qinghua Yu, Agda Karina Eterovic, Lauren A. Byers, Michael A. Davies, Wanleng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika M. von Euw, Dennis J. Slamon, Dylan Conklin, John V. Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yiling Lu, Gordon B. Mills, Han Liang

    Cyhoeddwyd 2017
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  13. 13
    Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

    Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy gan Tina Cascone, Jodi A. McKenzie, Rina M. Mbofung, Simone Punt, Zhe Wang, Chunyu Xu, Leila J. Williams, Zhiqiang Wang, Christopher A. Bristow, Alessandro Carugo, Michael Peoples, Lerong Li, Tatiana V. Karpinets, Lu Huang, Shruti Malu, Caitlin Creasy, Sara Elizabeth Leahey, Jiong Chen, Yuan Chen, Helen Pelicano, Chantale Bernatchez, Y.N. Vashisht Gopal, Timothy P. Heffernan, Jianhua Hu, Jing Wang, Rodabe N. Amaria, Levi A. Garraway, Peng Huang, Peiying Yang, Ignacio I. Wistuba, Scott E. Woodman, Jason Roszik, R. Eric Davis, Michael A. Davies, John V. Heymach, Patrick Hwu, Weiyi Peng

    Cyhoeddwyd 2018
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  14. 14
    Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

    Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases gan Grant M. Fischer, Ali Jalali, David A. Kircher, Won‐Chul Lee, Jennifer L. McQuade, Lauren E. Haydu, Aron Y. Joon, Alexandre Reuben, Mariana Petaccia de Macêdo, Fernando C. L. Carapeto, Chendong Yang, Anuj Srivastava, Chandrashekar R. Ambati, Arun Sreekumar, Courtney W. Hudgens, Barbara Knighton, Wanleng Deng, Sherise D. Ferguson, Hussein A. Tawbi, Isabella C. Glitza, Jeffrey E. Gershenwald, Y.N. Vashisht Gopal, Patrick Hwu, Jason T. Huse, Jennifer A. Wargo, P. Andrew Futreal, Nagireddy Putluri, Alexander J. Lazar, Ralph J. DeBerardinis, Joseph R. Marszalek, Jianjun Zhang, Sheri L. Holmen, Michael T. Tetzlaff, Michael A. Davies

    Cyhoeddwyd 2019
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  15. 15
    Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

    Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma gan Andrew W. Hahn, Ashley V. Menk, Dayana B. Rivadeneira, Ryan C. Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K. Mishra, Tuba N. Gide, Camelia Quek, Yan Zang, Christine N. Spencer, Alexander M. Menzies, Carrie R. Daniel, Courtney W. Hudgens, Theodore S. Nowicki, Lauren E. Haydu, M.A. Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M. Burton, Jared Malke, Julie M. Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E. Woodman, Y.N. Vashisht Gopal, Renato Guerrieri, Grant M. Fischer, Jian Wang, Khalida Wani, John F. Thompson, Jeffrey E. Lee, Patrick Hwu, Nadim J. Ajami, Jeffrey E. Gershenwald, Georgina V. Long, Richard A. Scolyer, Michael T. Tetzlaff, Alexander J. Lazar, Dirk Schadendorf, Jennifer A. Wargo, John M. Kirkwood, Ralph J. DeBerardinis, Han Liang, P. Andrew Futreal, Jianhua Zhang, James S. Wilmott, Weiyi Peng, Michael A. Davies, Greg M. Delgoffe, Yana G. Najjar, Jennifer L. McQuade

    Cyhoeddwyd 2022
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