Resultats de la cerca - Xiao-Jiang Li

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  1. 1
    Multiple pathways contribute to the pathogenesis of Huntington disease.

    Multiple pathways contribute to the pathogenesis of Huntington disease. per Shihua Li, Xiao‐Jiang Li

    Publicat 2006
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  2. 2
    Proteasomal dysfunction in aging and Huntington disease

    Proteasomal dysfunction in aging and Huntington disease per Xiao‐Jiang Li, Shihua Li

    Publicat 2010
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  3. 3
    Chaperone Suppression of Cellular Toxicity of Huntingtin Is Independent of Polyglutamine Aggregation

    Chaperone Suppression of Cellular Toxicity of Huntingtin Is Independent of Polyglutamine Aggregation per Hui Zhou, Shihua Li, Xiao‐Jiang Li

    Publicat 2001
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  4. 4
    Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity

    Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity per Su Yang, Shihua Li, Xiao‐Jiang Li

    Publicat 2018
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  5. 5
    A CRISPR monkey model unravels a unique function of PINK1 in primate brains

    A CRISPR monkey model unravels a unique function of PINK1 in primate brains per Weili Yang, Shihua Li, Xiao‐Jiang Li

    Publicat 2019
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  6. 6
    Impaired mitochondrial trafficking in Huntington's disease

    Impaired mitochondrial trafficking in Huntington's disease per Xiao‐Jiang Li, Adam L. Orr, Shihua Li

    Publicat 2009
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  7. 7
    Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review

    Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review per Ting Zhao, Yan Hong, Xiao‐Jiang Li, Shihua Li

    Publicat 2016
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  8. 8
    CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases

    CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases per Weili Yang, Zhuchi Tu, Qiang Sun, Xiao‐Jiang Li

    Publicat 2016
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  9. 9
    Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP

    Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP per Yan Hong, Ting Zhao, Xiao‐Jiang Li, Shihua Li

    Publicat 2016
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  10. 10
    Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes

    Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes per Yan Hong, Ting Zhao, Xiao‐Jiang Li, Shihua Li

    Publicat 2017
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  11. 11
    New pathogenic insights from large animal models of neurodegenerative diseases

    New pathogenic insights from large animal models of neurodegenerative diseases per Peng Yin, Shihua Li, Xiao‐Jiang Li, Weili Yang

    Publicat 2022
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  12. 12
    Neuroinflammation in Huntington’s disease: From animal models to clinical therapeutics

    Neuroinflammation in Huntington’s disease: From animal models to clinical therapeutics per Qingqing Jia, Shihua Li, Xiao‐Jiang Li, Peng Yin

    Publicat 2022
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  13. 13
    Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges

    Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges per Longhong Zhu, Shihua Li, Xiao‐Jiang Li, Peng Yin

    Publicat 2023
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  14. 14
    Genetically modified non-human primate models for research on neurodegenerative diseases

    Genetically modified non-human primate models for research on neurodegenerative diseases per Ming-Tian Pan, Han Zhang, Xiao‐Jiang Li, Xiangyu Guo

    Publicat 2024
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  15. 15
    Interaction of Huntingtin-Associated Protein with Dynactin P150<sup>Glued</sup>

    Interaction of Huntingtin-Associated Protein with Dynactin P150<sup>Glued</sup> per Shihua Li, Claire-Anne Gutekunst, Steven M. Hersch, Xiao-Jiang Li

    Publicat 1998
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  16. 16
    CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases

    CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases per Zhuchi Tu, Weili Yang, Sen Yan, Xiangyu Guo, Xiao‐Jiang Li

    Publicat 2015
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  17. 17
    Polyglutamine Expansion Reduces the Association of TATA-binding Protein with DNA and Induces DNA Binding-independent Neurotoxicity

    Polyglutamine Expansion Reduces the Association of TATA-binding Protein with DNA and Induces DNA Binding-independent Neurotoxicity per Meyer J. Friedman, Chuan-En Wang, Xiao‐Jiang Li, Shihua Li

    Publicat 2008
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  18. 18
    Interaction of Huntingtin-associated Protein-1 with Kinesin Light Chain

    Interaction of Huntingtin-associated Protein-1 with Kinesin Light Chain per John R. McGuire, Juan Rong, Shihua Li, Xiao‐Jiang Li

    Publicat 2005
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  19. 19
    Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins

    Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins per Ting Zhao, Yan Hong, Peng Yin, Shihua Li, Xiao‐Jiang Li

    Publicat 2017
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  20. 20
    PINK1-PRKN mediated mitophagy: differences between <i>in vitro</i> and <i>in vivo</i> models

    PINK1-PRKN mediated mitophagy: differences between <i>in vitro</i> and <i>in vivo</i> models per Rui Han, Yanting Liu, Shihua Li, Xiao‐Jiang Li, Weili Yang

    Publicat 2022
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