Resultats de la cerca - Xiao‐Fen Chen

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  1. 1
    The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer’s Disease

    The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer’s Disease per Li Zhong, Xiao‐Fen Chen

    Publicat 2019
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  2. 2
    Transcriptional regulation and its misregulation in Alzheimer’s disease

    Transcriptional regulation and its misregulation in Alzheimer’s disease per Xiao‐Fen Chen, Yun‐wu Zhang, Huaxi Xu, Guojun Bu

    Publicat 2013
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  3. 3
    TREM2 and sTREM2 in Alzheimer’s disease: from mechanisms to therapies

    TREM2 and sTREM2 in Alzheimer’s disease: from mechanisms to therapies per Lianshuai Zhang, Xianyuan Xiang, Y. Li, Guojun Bu, Xiao‐Fen Chen

    Publicat 2025
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  4. 4
    TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

    TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism per Honghua Zheng, Baoying Cheng, Yanfang Li, Xin Li, Xiao‐Fen Chen, Yun‐wu Zhang

    Publicat 2018
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  5. 5
    Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice

    Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice per Jin Hu, Chia‐Chen Liu, Xiao‐Fen Chen, Yun‐wu Zhang, Huaxi Xu, Guojun Bu

    Publicat 2015
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  6. 6
    The Rpd3 Core Complex Is a Chromatin Stabilization Module

    The Rpd3 Core Complex Is a Chromatin Stabilization Module per Xiao‐Fen Chen, Benjamin G. Kuryan, Tasuku Kitada, Nancy Tran, Jingyu Li, Siavash K. Kurdistani, Michael Grunstein, Bing Li, Michael Carey

    Publicat 2011
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  7. 7
    DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response

    DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response per Li Zhong, Xiao‐Fen Chen, Zhen-Lian Zhang, Zhe Wang, Xin-Zhen Shi, Kai Xu, Yun‐wu Zhang, Huaxi Xu, Guojun Bu

    Publicat 2015
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  8. 8
    A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism

    A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism per Li Zhong, Yong-Zhuang Xie, Tian-Tian Cao, Zongqi Wang, Tingting Wang, Xinxiu Li, Rui-Chi Shen, Huaxi Xu, Guojun Bu, Xiao‐Fen Chen

    Publicat 2016
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  9. 9
    TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway

    TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway per Li Zhong, Zhen-Lian Zhang, Xinxiu Li, Chunyan Liao, Pengfei Mou, Tingting Wang, Zongqi Wang, Zhe Wang, Min Wei, Huaxi Xu, Guojun Bu, Xiao‐Fen Chen

    Publicat 2017
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  10. 10
    LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways

    LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways per Longyu Yang, Chia‐Chen Liu, Honghua Zheng, Takahisa Kanekiyo, Yuka Atagi, Lin Jia, Daxin Wang, Aurelie N’Songo, Dan Can, Huaxi Xu, Xiao‐Fen Chen, Guojun Bu

    Publicat 2016
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  11. 11
    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway

    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway per Honghua Zheng, Lin Jia, Chia‐Chen Liu, Zhouyi Rong, Li Zhong, Longyu Yang, Xiao‐Fen Chen, John Denis Fryer, Xin Wang, Yun‐wu Zhang, Huaxi Xu, Guojun Bu

    Publicat 2017
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  12. 12
    CTL- vs Treg lymphocyte-attracting chemokines, CCL4 and CCL20, are strong reciprocal predictive markers for survival of patients with oesophageal squamous cell carcinoma

    CTL- vs Treg lymphocyte-attracting chemokines, CCL4 and CCL20, are strong reciprocal predictive markers for survival of patients with oesophageal squamous cell carcinoma per J Y Liu, F. Li, L. P. Wang, Xiao‐Fen Chen, D Wang, Lei Cao, Ping Yü, Shunxin Zhao, Bingle Li, Stephen H. Thorne, B Zhang, Paweł Kaliński, Yi Zhang

    Publicat 2015
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  13. 13
    Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

    Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2) per Li Zhong, Zongqi Wang, Daxin Wang, Zhe Wang, Yuka A. Martens, Linbei Wu, Ying Xu, Kai Wang, Jianguo Li, Ruizhi Huang, Dan Can, Huaxi Xu, Guojun Bu, Xiao‐Fen Chen

    Publicat 2018
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  14. 14
    Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

    Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) per Yuka Atagi, Chia‐Chen Liu, Meghan M. Painter, Xiao‐Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S. Kang, Huaxi Xu, Steven G. Younkin, Pritam Das, John Denis Fryer, Guojun Bu

    Publicat 2015
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  15. 15
    Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation

    Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation per Honghua Zheng, Chia‐Chen Liu, Yuka Atagi, Xiao‐Fen Chen, Lin Jia, Longyu Yang, Wencan He, Xilin Zhang, Silvia S. Kang, Terrone L. Rosenberry, John Denis Fryer, Yun‐wu Zhang, Huaxi Xu, Guojun Bu

    Publicat 2016
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  16. 16
    Soluble TREM2 induces inflammatory responses and enhances microglial survival

    Soluble TREM2 induces inflammatory responses and enhances microglial survival per Li Zhong, Xiao‐Fen Chen, Tingting Wang, Zhe Wang, Chunyan Liao, Zongqi Wang, Ruizhi Huang, Daxin Wang, Xinxiu Li, Linbei Wu, Lin Jia, Honghua Zheng, Meghan M. Painter, Yuka Atagi, Chia‐Chen Liu, Yun‐wu Zhang, John Denis Fryer, Huaxi Xu, Guojun Bu

    Publicat 2017
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  17. 17
    TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration

    TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration per Li Zhong, Xuan Sheng, Wanbing Wang, Yanzhong Li, Rengong Zhuo, Kai Wang, Lianshuai Zhang, Dandan Hu, Yujuan Hong, Linting Chen, Hengjun Rao, Tingting Li, Muyang Chen, Zhihao Lin, Yun‐wu Zhang, Xin Wang, Xiao‐Xin Yan, Xiaochun Chen, Guojun Bu, Xiao‐Fen Chen

    Publicat 2023
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  18. 18
    Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model

    Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model per Li Zhong, Ying Xu, Rengong Zhuo, Tingting Wang, Kai Wang, Ruizhi Huang, Daxin Wang, Yue Gao, Yifei Zhu, Xuan Sheng, Kai Chen, Na Wang, Lin Zhu, Dan Can, Yuka Marten, Mitsuru Shinohara, Chia‐Chen Liu, Dan Du, Hao Sun, Lei Wen, Huaxi Xu, Guojun Bu, Xiao‐Fen Chen

    Publicat 2019
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