Search Results - X. William Yang

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  1. 1
    “Huntingtin Holiday”: Progress toward an Antisense Therapy for Huntington's Disease

    “Huntingtin Holiday”: Progress toward an Antisense Therapy for Huntington's Disease by Xiao‐Hong Lu, X. William Yang

    Published 2012
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  2. 2
    Molecular insights into cortico-striatal miscommunications in Huntington's disease

    Molecular insights into cortico-striatal miscommunications in Huntington's disease by Matthew B. Veldman, X. William Yang

    Published 2017
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  3. 3
    Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease

    Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease by Jay Spampanato, Xiaofeng Gu, X. William Yang, István Módy

    Published 2008
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  4. 4
    Highly Efficient Modification of Bacterial Artificial Chromosomes (BACs) Using Novel Shuttle Vectors Containing the R6Kγ Origin of Replication

    Highly Efficient Modification of Bacterial Artificial Chromosomes (BACs) Using Novel Shuttle Vectors Containing the R6Kγ Origin of Replication by Shiaoching Gong, X. William Yang, Chenjian Li, Nathaniel Heintz

    Published 2002
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  5. 5
    Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis

    Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis by C. Y. Daniel Lee, Jeffrey P. Cantle, X. William Yang

    Published 2013
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  6. 6
    A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice

    A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice by Jiali Wu, Meiyan Wang, X William Yang, Chengwei Yi, Jian Jiang, Yuanhuan Yu, Haifeng Ye

    Published 2020
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  7. 7
    Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease

    Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease by Xiaofeng Gu, Véronique M. André, Carlos Cepeda, Shihua Li, Xiao‐Jiang Li, Michael S. Levine, X. William Yang

    Published 2007
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  8. 8
    Cortical Efferents Lacking Mutant huntingtin Improve Striatal Neuronal Activity and Behavior in a Conditional Mouse Model of Huntington's Disease

    Cortical Efferents Lacking Mutant huntingtin Improve Striatal Neuronal Activity and Behavior in a Conditional Mouse Model of Huntington's Disease by Ana María Estrada‐Sánchez, Courtney L. Burroughs, Stephen Cavaliere, Scott J. Barton, Shirley Chen, X William Yang, George V. Rebec

    Published 2015
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  9. 9
    The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington’s disease model

    The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington’s disease model by Matthew B. Veldman, Yesenia Rios-Galdamez, Xiao‐Hong Lu, Xiaofeng Gu, Wei Qin, Song Li, X. William Yang, Shuo Lin

    Published 2015
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  10. 10
    Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington’s disease

    Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington’s disease by Abhishek Chandra, Abhijeet Sharma, Noel Y. Calingasan, Joshua M. White, Yevgeniya I. Shurubor, X. William Yang, M. Flint Beal, Ashu Johri

    Published 2016
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  11. 11
    MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice

    MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice by Peter Langfelder, Fuying Gao, Nan Wang, David Howland, Seung Kwak, Thomas Vogt, Jeffrey S. Aaronson, Jim Rosinski, Giovanni Coppola, Steve Horvath, X. William Yang

    Published 2018
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  12. 12
    Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

    Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice by Xiaofeng Gu, Erin R. Greiner, Rakesh K. Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S. Steffan, Leslie M. Thompson, Ronald Wetzel, X. William Yang

    Published 2009
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  13. 13
    P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus

    P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus by Ji Xu, Alexander M. Bernstein, Angela Wong, Xiao‐Hong Lu, Sheraz Khoja, X. William Yang, Daryl L. Davies, Paul E. Micevych, Michael V. Sofroniew, Baljit S. Khakh

    Published 2016
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  14. 14
    Pathological Cell-Cell Interactions Elicited by a Neuropathogenic Form of Mutant Huntingtin Contribute to Cortical Pathogenesis in HD Mice

    Pathological Cell-Cell Interactions Elicited by a Neuropathogenic Form of Mutant Huntingtin Contribute to Cortical Pathogenesis in HD Mice by Xiaofeng Gu, Chenjian Li, Weizheng Wei, Victor Lo, Shiaoching Gong, Shi-Hua Li, Takuji Iwasato, Shigeyoshi Itohara, Xiao‐Jiang Li, István Módy, Nathaniel Heintz, X. William Yang

    Published 2005
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  15. 15
    Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control

    Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control by Richard G. Yau, Kerstin Doerner, Erick R. Castellanos, Diane L. Haakonsen, Achim Werner, Nan Wang, X. William Yang, Nadia Martinez-Martín, M Matsumoto, Vishva M. Dixit, Michael Rapé

    Published 2017
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  16. 16
    Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes

    Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes by Matheus B. Victor, Michelle Richner, Hannah E. Olsen, Seong Won Lee, Alejandro Mas Monteys, Chunyu Ma, Christine J. Huh, Bo Zhang, Beverly L. Davidson, X. William Yang, Andrew S. Yoo

    Published 2018
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  17. 17
    Deletion of Astroglial Dicer Causes Non-Cell-Autonomous Neuronal Dysfunction and Degeneration

    Deletion of Astroglial Dicer Causes Non-Cell-Autonomous Neuronal Dysfunction and Degeneration by Jifang Tao, Hao Wu, Quan Lin, Weizheng Wei, Xiao‐Hong Lu, Jeffrey P. Cantle, Yan Ao, Richard W. Olsen, X. William Yang, István Módy, Michael V. Sofroniew, Yi Eve Sun

    Published 2011
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  18. 18
    Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

    Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice by Michael A. Gray, Dyna Shirasaki, Carlos Cepeda, Véronique André, B. Wilburn, X.-H. Lu, Jiadong Tao, Iwao Yamazaki, S.-H. Li, Y. E. Sun, Xing Li, Michael S. Levine, X. William Yang

    Published 2008
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  19. 19
    Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumulation of Proteinase K-Resistant α-Synuclein

    Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumul... by Xiao-Hong Lu, Sheila M. Fleming, Bernhard H. Meurers, Larry C. Ackerson, Farzad Mortazavi, Victor Lo, Daniela Hernandez, David Sulzer, George R. Jackson, Nigel T. Maidment, Marie-Françoise Chesselet, X. William Yang

    Published 2009
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  20. 20
    Serine 421 regulates mutant huntingtin toxicity and clearance in mice

    Serine 421 regulates mutant huntingtin toxicity and clearance in mice by Ian H. Kratter, Hengameh Zahed, Alice Lau, Andrey S. Tsvetkov, Aaron Daub, Kurt F. Weiberth, Xiaofeng Gu, Frédéric Saudou, Sandrine Humbert, X. William Yang, Alex Osmand, Joan S. Steffan, Eliezer Masliah, Steven Finkbeiner

    Published 2016
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