Výsledky vyhledávání - Wayne Blosser

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  1. 1
    LY2228820 Dimesylate, a Selective Inhibitor of p38 Mitogen-activated Protein Kinase, Reduces Angiogenic Endothelial Cord Formation in Vitro and in Vivo

    LY2228820 Dimesylate, a Selective Inhibitor of p38 Mitogen-activated Protein Kinase, Reduces Angiogenic Endothelial Cord Formation in Vitro and in Vivo Autor Courtney M. Tate, Wayne Blosser, Lisa Wyss, Glenn F. Evans, Qi Xue, Yong Pan, Louis F. Stancato

    Vydáno 2013
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  2. 2
    LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms

    LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms Autor Constance King, H. Bruce Diaz, Samuel McNeely, Darlene Barnard, Jack Dempsey, Wayne Blosser, Richard P. Beckmann, David A. Barda, Mark S. Marshall

    Vydáno 2015
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  3. 3
    The Checkpoint Kinase 1 Inhibitor Prexasertib Induces Regression of Preclinical Models of Human Neuroblastoma

    The Checkpoint Kinase 1 Inhibitor Prexasertib Induces Regression of Preclinical Models of Human Neuroblastoma Autor Caitlin D. Lowery, Alle B. VanWye, Michele Dowless, Wayne Blosser, Beverly L. Falcón, Julie Stewart, Jennifer R. Stephens, Richard P. Beckmann, Aimee Bence Lin, Louis F. Stancato

    Vydáno 2017
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  4. 4
    LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer

    LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer Autor Eliza Vakana, Susan E. Pratt, Wayne Blosser, Michele Dowless, Nicholas Simpson, Xiu‐Juan Yuan, Susan Jaken, Jason R. Manro, Jennifer R. Stephens, Youyan Zhang, Lysiane Huber, Sheng-Bin Peng, Louis F. Stancato

    Vydáno 2016
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  5. 5
    Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling

    Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling Autor Michele Dowless, Caitlin D. Lowery, Terry J. Shackleford, Matthew Renschler, Jennifer Stephens, Robert S. Flack, Wayne Blosser, Simone Gupta, Julie Stewart, Yue Webster, Jack Dempsey, Alle B. VanWye, Philip J. Ebert, Philip W. Iversen, Jonathan B. Olsen, Xueqian Gong, Sean G. Buchanan, Peter J. Houghton, Louis F. Stancato

    Vydáno 2018
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  6. 6
    Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models

    Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models Autor Caitlin D. Lowery, Michele Dowless, Matthew Renschler, Wayne Blosser, Alle B. VanWye, Jennifer R. Stephens, Philip W. Iversen, Aimee Bence Lin, Richard P. Beckmann, Kateryna Krytska, Kristina A. Cole, John M. Maris, Douglas S. Hawkins, Brian P. Rubin, Raushan T. Kurmasheva, Peter J. Houghton, Richard Görlick, E. Anders Kolb, Min H. Kang, C. Patrick Reynolds, Stephen W. Erickson, Beverly A. Teicher, Malcolm A. Smith, Louis F. Stancato

    Vydáno 2018
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  7. 7
    RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies

    RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies Autor Benjamin Solomon, Lavinia Tan, W. Marston Linehan, Stephen Q. Wong, Sebastian Hollizeck, Kevin Ebata, Brian B. Tuch, Satoshi Yoda, Justin F. Gainor, Lecia V. Sequist, Geoffrey R. Oxnard, Oliver Gautschi, Alexander Drilon, Vivek Subbiah, Christine Khoo, Edward Y. Zhu, Michele Nguyen, Dahlia Henry, Kevin R. Condroski, Gabrielle R. Kolakowski, Eliana B Gómez, Joshua A. Ballard, Andrew T. Metcalf, James F. Blake, Sarah‐Jane Dawson, Wayne Blosser, Louis F. Stancato, Barbara J. Brandhuber, Steve Andrews, Bruce G. Robinson, S. Michael Rothenberg

    Vydáno 2020
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  8. 8
    Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the <i>RB1</i> Tumor Suppressor Gene

    Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the <i>RB1</i> Tumor Suppressor Gene Autor Xueqian Gong, Jian Du, Stephen H. Parsons, Farhana F. Merzoug, Yue Webster, Philip W. Iversen, Li-Chun Chio, Robert D. Van Horn, Xi Lin, Wayne Blosser, Bomie Han, Shaoling Jin, Sufang Yao, Huimin Bian, Chris Ficklin, Fan Li, Avnish Kapoor, Stephen Antonysamy, Ann Mc Nulty, Karen Froning, Danalyn Manglicmot, Anna Pustilnik, Kenneth Weichert, Stephen R. Wasserman, Michele Dowless, Carlos Marugán, Carmen Baquero, Marı́a José Lallena, Scott W. Eastman, Yu‐Hua Hui, Matthew Z. Dieter, Thompson N. Doman, Shaoyou Chu, Hui-Rong Qian, Xiang S. Ye, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Robert M. Campbell, James R. Henry, Sean G. Buchanan

    Vydáno 2018
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