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Raf promotes dimerization of the Ras G-domain with increased allosteric connections by Morgan Packer, Jillian A. Parker, Jean K. Chung, Zhenlu Li, Young Kwang Lee, Trinity Cookis, Hugo Guterres, Steven Alvarez, Md Amin Hossain, Daniel P. Donnelly, Jeffrey N. Agar, Lee Makowski, Matthias Buck, Jay T. Groves, Carla Mattos
Published 2021Artigo
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Biology
Chemistry
Biochemistry
Cell biology
Gene
Allosteric regulation
Anti-apoptotic Ras signalling cascade
Chromatin
Computational biology
Crystal structure
Crystallography
DNA
DNA methylation
Dimer
Enzyme
Enzyme activator
GTPase
Gene expression
Genetics
Gibbs isotherm
H3K4me3
HRAS
Histone
Histone H2A
Histone H3
Histone methylation
Interface (matter)
KRAS
Kinase
MAPK/ERK pathway