Výsledky vyhledávání - Tony Taldone

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  1. 1
    Purine-Scaffold Hsp90 Inhibitors

    Purine-Scaffold Hsp90 Inhibitors Autor Tony Taldone, Gabriela Chiosis

    Vydáno 2009
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  2. 2
    Discovery and development of heat shock protein 90 inhibitors

    Discovery and development of heat shock protein 90 inhibitors Autor Tony Taldone, Weilin Sun, Gabriela Chiosis

    Vydáno 2008
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  3. 3
    Targeting Hsp90: small-molecule inhibitors and their clinical development

    Targeting Hsp90: small-molecule inhibitors and their clinical development Autor Tony Taldone, Alexander Gozman, Ronnie Maharaj, Gabriela Chiosis

    Vydáno 2008
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  4. 4
    Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers

    Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers Autor Komal Jhaveri, Tony Taldone, Shanu Modi, Gabriela Chiosis

    Vydáno 2011
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  5. 5
    Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment

    Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment Autor Hardik Patel, Shanu Modi, Gabriela Chiosis, Tony Taldone

    Vydáno 2011
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  6. 6
    Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

    Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease Autor Liza Shrestha, Alexander Bolaender, Hardik Patel, Tony Taldone

    Vydáno 2016
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  7. 7
    Selective targeting of the stress chaperome as a therapeutic strategy

    Selective targeting of the stress chaperome as a therapeutic strategy Autor Tony Taldone, Stefan O. Ochiana, Pallav D. Patel, Gabriela Chiosis

    Vydáno 2014
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  8. 8
    Heat shock protein 90 in neurodegenerative diseases

    Heat shock protein 90 in neurodegenerative diseases Autor Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis

    Vydáno 2010
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  9. 9
    Synthesis of Reblastatin, Autolytimycin, and Non-Benzoquinone Analogues: Potent Inhibitors of Heat Shock Protein 90

    Synthesis of Reblastatin, Autolytimycin, and Non-Benzoquinone Analogues: Potent Inhibitors of Heat Shock Protein 90 Autor Iwona Wrona, Alexander Gozman, Tony Taldone, Gabriela Chiosis, James S. Panek

    Vydáno 2010
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  10. 10
    Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab

    Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab Autor Jason P. Holland, Eloisi Caldas-Lopes, Vadim Divilov, Valerie A. Longo, Tony Taldone, Danuta Zatorska, Gabriela Chiosis, Jason S. Lewis

    Vydáno 2010
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  11. 11
    Design, synthesis, and evaluation of small molecule Hsp90 probes

    Design, synthesis, and evaluation of small molecule Hsp90 probes Autor Tony Taldone, Danuta Zatorska, Pallav D. Patel, Hongliang Zong, Anna Rodina, James H. Ahn, Kamalika Moulick, Mónica L. Guzmán, Gabriela Chiosis

    Vydáno 2011
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  12. 12
    Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

    Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series Autor Tony Taldone, Pallav D. Patel, Maulik Patel, Hardik J. Patel, Christopher E. B. Evans, Anna Rodina, Stefan O. Ochiana, Smit Shah, Mohammad Uddin, D.T. Gewirth, Gabriela Chiosis

    Vydáno 2013
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  13. 13
    Pre‐clinical efficacy of PU‐H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

    Pre‐clinical efficacy of PU‐H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma Autor Srikanth R. Ambati, Eloisi Caldas Lopes, Kohji Kosugi, Ullas Mony, Ahmet Zehir, Smit Shah, Tony Taldone, André L. Moreira, Paul A. Meyers, Gabriela Chiosis, Malcolm A.S. Moore

    Vydáno 2013
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  14. 14
    Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

    Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2 Autor Pallav D. Patel, Pengrong Yan, Paul M. Seidler, Hardik J. Patel, Weilin Sun, Chenghua Yang, Nanette S. Que, Tony Taldone, Paola Finotti, Ralph A. Stephani, D.T. Gewirth, Gabriela Chiosis

    Vydáno 2013
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  15. 15
    Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

    Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70 Autor Yanlong Kang, Tony Taldone, Hardik J. Patel, Pallav D. Patel, Anna Rodina, Alexander Gozman, Ronnie Maharaj, Cristina C. Clement, Maulik Patel, Jeffrey L. Brodsky, Jason C. Young, Gabriela Chiosis

    Vydáno 2014
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  16. 16
    Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

    Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an All... Autor Tony Taldone, Yanlong Kang, Hardik J. Patel, Maulik Patel, Pallav D. Patel, Anna Rodina, Yogita Patel, Alexander Gozman, Ronnie Maharaj, Cristina C. Clement, Alvin Lu, Jason C. Young, Gabriela Chiosis

    Vydáno 2014
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  17. 17
    A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond

    A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond Autor Tony Taldone, Tai Wang, Anna Rodina, Nagavarakishore Pillarsetty, Chander Singh Digwal, Sahil Sharma, Pengrong Yan, Suhasini Joshi, Piyusha P. Pagare, Alexander Bolaender, Gail J. Roboz, Mónica L. Guzmán, Gabriela Chiosis

    Vydáno 2019
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  18. 18
    Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies

    Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies Autor Utthara Nayar, Pin Lü, Rebecca Goldstein, Jelena Vider, Gianna Ballon, Anna Rodina, Tony Taldone, Hediye Erdjument‐Bromage, Max Chomet, Ronald Blasberg, Ari Melnick, Leandro Cerchietti, Gabriela Chiosis, Y. Lynn Wang, Ethel Cesarman

    Vydáno 2013
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  19. 19
    Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms

    Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms Autor Neha Bhagwat, Priya Koppikar, Matthew D. Keller, Sachie Marubayashi, Kaitlyn Shank, Raajit K. Rampal, Jun Qi, Maria Kleppe, Hardik J. Patel, Smit Shah, Tony Taldone, James E. Bradner, Gabriela Chiosis, Ross L. Levine

    Vydáno 2014
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  20. 20
    Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation

    Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation Autor Sun Young Chung, Sarah Kishinevsky, Joseph R. Mazzulli, John J. Graziotto, Ana Mrejeru, Eugene V. Mosharov, Lesly Puspita, Parvin Valiulahi, David Sulzer, Teresa A. Milner, Tony Taldone, Dimitri Krainc, Lorenz Studer, Jae-won Shim

    Vydáno 2016
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