检索结果 - Tobie D. Lee
- Showing 1 - 10 results of 10
-
1
-
2
-
3
-
4
Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen–Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based D... 由 Scott J. Eron, Hongwei Huang, Roman V. Agafonov, Mark E. Fitzgerald, Joe Patel, Ryan E. Michael, Tobie D. Lee, Ashley Hart, Jodi Shaulsky, Christopher G. Nasveschuk, Andrew J. Phillips, Stewart L. Fisher, Andrew C. Good
出版 2021Artigo -
5
Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors 由 Jason M. Rohde, Kyle R. Brimacombe, Li Liu, Michael E. Pacold, Adam Yasgar, Dorian M. Cheff, Tobie D. Lee, Ganesha Rai, Bolormaa Baljinnyam, Zhuyin Li, Anton Simeonov, Matthew D. Hall, Min Shen, David M. Sabatini, Matthew B. Boxer
出版 2018Artigo -
6
Pan-cancer proteogenomics expands the landscape of therapeutic targets 由 Sara R. Savage, Xinpei Yi, Jonathan T. Lei, Bo Wen, Hongwei Zhao, Yuxing Liao, Eric J. Jaehnig, Lauren K. Somes, Paul Shafer, Tobie D. Lee, Zile Fu, Yongchao Dou, Zhiao Shi, Daming Gao, Valentina Hoyos, Qiang Gao, Bing Zhang
出版 2024Artigo -
7
Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays 由 Daniel J. Urban, Natalia J. Martinez, Mindy I. Davis, Kyle R. Brimacombe, Dorian M. Cheff, Tobie D. Lee, Mark J. Henderson, Steven A. Titus, Rajan Pragani, Jason M. Rohde, Li Liu, Yuhong Fang, Karavadhi Surendra, Pranav Shah, Olivia W. Lee, Amy Wang, Andrew L. McIver, Hongchao Zheng, Xiaodong Wang, Xin Xu, Ajit Jadhav, Anton Simeonov, Min Shen, Matthew B. Boxer, Matthew D. Hall
出版 2017Artigo -
8
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH) 由 Ganesha Rai, Kyle R. Brimacombe, Bryan T. Mott, Daniel J. Urban, Xin Hu, Shyh‐Ming Yang, Tobie D. Lee, Dorian M. Cheff, Jennifer Kouznetsova, Gloria A. Benavides, Katie Pohida, Eric J. Kuenstner, Diane K. Luci, Christine Lukacs, D.R. Davies, David M. Dranow, Hu Zhu, Gary A. Sulikowski, William Moore, Gordon M. Stott, Andrew Flint, Matthew D. Hall, Victor Darley‐Usmar, Leonard Μ. Neckers, Chi V. Dang, Alex G. Waterson, Anton Simeonov, Ajit Jadhav, David J. Maloney
出版 2017Artigo -
9
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers 由 Lei Shi, William Shen, Mindy I. Davis, Ke Kong, Phuong Vu, Supriya K. Saha, Ramzi Adil, Johannes Kreuzer, Regina K. Egan, Tobie D. Lee, Patricia Greninger, Jonathan H. Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weeresekara, Hiroshi Kondo, Vindhya Vijay, Meng‐Ju Wu, Sara E. Kearney, Jeffrey D. Ho, Joseph McClanaghan, Ellen Murchie, Giovanna Stein Crowther, Samarjit Patnaik, Matthew B. Boxer, Min Shen, David T. Ting, William Y. Kim, Ben Z. Stanger, Vikram Deshpande, Cristina R. Ferrone, Cyril H. Benes, Wilhelm Haas, Matthew D. Hall, Nabeel Bardeesy
出版 2023Artigo -
10
Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties 由 Ganesha Rai, Daniel J. Urban, Bryan T. Mott, Xin Hu, Shyh‐Ming Yang, Gloria A. Benavides, Michelle S. Johnson, Giuseppe L. Squadrito, Kyle R. Brimacombe, Tobie D. Lee, Dorian M. Cheff, Hu Zhu, Mark J. Henderson, Katherine Pohida, Gary A. Sulikowski, David M. Dranow, Md Kabir, Pranav Shah, Elias Carvalho Padilha, Dingyin Tao, Yuhong Fang, Plamen P. Christov, Kwang‐Ho Kim, Somnath Jana, Pavan Muttil, Tamara L. Anderson, Nitesh K. Kunda, Helen J. Hathaway, Donna F. Kusewitt, Nobu Oshima, Murali Cherukuri, D.R. Davies, Jeffrey P. Norenberg, Larry A. Sklar, William Moore, Chi V. Dang, Gordon M. Stott, Leonard Μ. Neckers, Andrew Flint, Victor Darley‐Usmar, Anton Simeonov, Alex G. Waterson, Ajit Jadhav, Matthew D. Hall, David J. Maloney
出版 2020Artigo
相关主题
Biochemistry
Chemistry
Enzyme
Biology
Computational biology
Cancer research
Gene
Genetics
In vitro
Medicine
Cancer
Pharmacology
ADME
Bioinformatics
Dehydrogenase
Drug discovery
Glycolysis
Lactate dehydrogenase
Pyrazole
Small molecule
Stereochemistry
Antibody
CRISPR
Cancer cell
Carboplatin
Cas9
Catalysis
Chemotherapy
Chromatography
Cisplatin