Resultats de la cerca - Tobie D. Lee

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  1. 1
    Functional Analysis of Rhomboid Proteases during <i>Toxoplasma</i> Invasion

    Functional Analysis of Rhomboid Proteases during <i>Toxoplasma</i> Invasion per Bang Shen, Jeffrey S. Buguliskis, Tobie D. Lee, L. David Sibley

    Publicat 2014
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  2. 2
    Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9

    Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9 per Bang Shen, Kevin M. Brown, Tobie D. Lee, L. David Sibley

    Publicat 2014
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  3. 3
    Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes

    Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes per Matthew D. Hall, Katherine A. Telma, Ki-Eun Chang, Tobie D. Lee, James P. Madigan, John R. Lloyd, Ian S. Goldlust, James D. Hoeschele, Michael M. Gottesman

    Publicat 2014
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  4. 4
    Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen–Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design

    Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen–Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based D... per Scott J. Eron, Hongwei Huang, Roman V. Agafonov, Mark E. Fitzgerald, Joe Patel, Ryan E. Michael, Tobie D. Lee, Ashley Hart, Jodi Shaulsky, Christopher G. Nasveschuk, Andrew J. Phillips, Stewart L. Fisher, Andrew C. Good

    Publicat 2021
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  5. 5
    Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors

    Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors per Jason M. Rohde, Kyle R. Brimacombe, Li Liu, Michael E. Pacold, Adam Yasgar, Dorian M. Cheff, Tobie D. Lee, Ganesha Rai, Bolormaa Baljinnyam, Zhuyin Li, Anton Simeonov, Matthew D. Hall, Min Shen, David M. Sabatini, Matthew B. Boxer

    Publicat 2018
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  6. 6
    Pan-cancer proteogenomics expands the landscape of therapeutic targets

    Pan-cancer proteogenomics expands the landscape of therapeutic targets per Sara R. Savage, Xinpei Yi, Jonathan T. Lei, Bo Wen, Hongwei Zhao, Yuxing Liao, Eric J. Jaehnig, Lauren K. Somes, Paul Shafer, Tobie D. Lee, Zile Fu, Yongchao Dou, Zhiao Shi, Daming Gao, Valentina Hoyos, Qiang Gao, Bing Zhang

    Publicat 2024
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  7. 7
    Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

    Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays per Daniel J. Urban, Natalia J. Martinez, Mindy I. Davis, Kyle R. Brimacombe, Dorian M. Cheff, Tobie D. Lee, Mark J. Henderson, Steven A. Titus, Rajan Pragani, Jason M. Rohde, Li Liu, Yuhong Fang, Karavadhi Surendra, Pranav Shah, Olivia W. Lee, Amy Wang, Andrew L. McIver, Hongchao Zheng, Xiaodong Wang, Xin Xu, Ajit Jadhav, Anton Simeonov, Min Shen, Matthew B. Boxer, Matthew D. Hall

    Publicat 2017
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  8. 8
    Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

    Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH) per Ganesha Rai, Kyle R. Brimacombe, Bryan T. Mott, Daniel J. Urban, Xin Hu, Shyh‐Ming Yang, Tobie D. Lee, Dorian M. Cheff, Jennifer Kouznetsova, Gloria A. Benavides, Katie Pohida, Eric J. Kuenstner, Diane K. Luci, Christine Lukacs, D.R. Davies, David M. Dranow, Hu Zhu, Gary A. Sulikowski, William Moore, Gordon M. Stott, Andrew Flint, Matthew D. Hall, Victor Darley‐Usmar, Leonard Μ. Neckers, Chi V. Dang, Alex G. Waterson, Anton Simeonov, Ajit Jadhav, David J. Maloney

    Publicat 2017
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  9. 9
    SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers

    SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers per Lei Shi, William Shen, Mindy I. Davis, Ke Kong, Phuong Vu, Supriya K. Saha, Ramzi Adil, Johannes Kreuzer, Regina K. Egan, Tobie D. Lee, Patricia Greninger, Jonathan H. Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weeresekara, Hiroshi Kondo, Vindhya Vijay, Meng‐Ju Wu, Sara E. Kearney, Jeffrey D. Ho, Joseph McClanaghan, Ellen Murchie, Giovanna Stein Crowther, Samarjit Patnaik, Matthew B. Boxer, Min Shen, David T. Ting, William Y. Kim, Ben Z. Stanger, Vikram Deshpande, Cristina R. Ferrone, Cyril H. Benes, Wilhelm Haas, Matthew D. Hall, Nabeel Bardeesy

    Publicat 2023
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  10. 10
    Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties

    Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties per Ganesha Rai, Daniel J. Urban, Bryan T. Mott, Xin Hu, Shyh‐Ming Yang, Gloria A. Benavides, Michelle S. Johnson, Giuseppe L. Squadrito, Kyle R. Brimacombe, Tobie D. Lee, Dorian M. Cheff, Hu Zhu, Mark J. Henderson, Katherine Pohida, Gary A. Sulikowski, David M. Dranow, Md Kabir, Pranav Shah, Elias Carvalho Padilha, Dingyin Tao, Yuhong Fang, Plamen P. Christov, Kwang‐Ho Kim, Somnath Jana, Pavan Muttil, Tamara L. Anderson, Nitesh K. Kunda, Helen J. Hathaway, Donna F. Kusewitt, Nobu Oshima, Murali Cherukuri, D.R. Davies, Jeffrey P. Norenberg, Larry A. Sklar, William Moore, Chi V. Dang, Gordon M. Stott, Leonard Μ. Neckers, Andrew Flint, Victor Darley‐Usmar, Anton Simeonov, Alex G. Waterson, Ajit Jadhav, Matthew D. Hall, David J. Maloney

    Publicat 2020
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