Hakutulokset - Takeshi Shimamura

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  1. 1
    Heat Shock Protein 90 Inhibition in Lung Cancer

    Heat Shock Protein 90 Inhibition in Lung Cancer Tekijä Takeshi Shimamura, Geoffrey I. Shapiro

    Julkaistu 2008
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  2. 2
    The IL-4 and IL-13 pseudomonas exotoxins: new hope for brain tumor therapy

    The IL-4 and IL-13 pseudomonas exotoxins: new hope for brain tumor therapy Tekijä Takeshi Shimamura, Syed R. Husain, Raj K. Puri

    Julkaistu 2006
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  3. 3
    Interleukin‐13 receptor α2 chain

    Interleukin‐13 receptor α2 chain Tekijä Mitomu Kioi, Mariko Kawakami, Takeshi Shimamura, Syed R. Husain, Raj K. Puri

    Julkaistu 2006
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  4. 4
    Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas

    Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas Tekijä Masaaki Takamura, Michlle Sakamoto, Yoshinori Ino, Takeshi Shimamura, Takafumi Ichida, Hitoshi Asakura, Setsuo Hirohashi

    Julkaistu 2003
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  5. 5
    Novel Role of IL-13 in Fibrosis Induced by Nonalcoholic Steatohepatitis and Its Amelioration by IL-13R-Directed Cytotoxin in a Rat Model

    Novel Role of IL-13 in Fibrosis Induced by Nonalcoholic Steatohepatitis and Its Amelioration by IL-13R-Directed Cytotoxin in a Rat Model Tekijä Takeshi Shimamura, Toshio Fujisawa, Syed R. Husain, Mitomu Kioi, Atsushi Nakajima, Raj K. Puri

    Julkaistu 2008
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  6. 6
    Proapoptotic BH3-Only BCL-2 Family Protein BIM Connects Death Signaling from Epidermal Growth Factor Receptor Inhibition to the Mitochondrion

    Proapoptotic BH3-Only BCL-2 Family Protein BIM Connects Death Signaling from Epidermal Growth Factor Receptor Inhibition to the Mitochondrion Tekijä Jing Deng, Takeshi Shimamura, Samanthi A. Perera, Nicole E. Carlson, Dongpo Cai, Geoffrey I. Shapiro, Kwok‐Kin Wong, Anthony Letai

    Julkaistu 2007
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  7. 7
    Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells

    Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells Tekijä Britta Will, Tanya Siddiqi, Meritxell Alberich‐Jorda, Takeshi Shimamura, Katarina Luptakova, Philipp B. Staber, Daniel B. Costa, Ulrich Steidl, Daniel G. Tenen, Susumu Kobayashi

    Julkaistu 2010
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  8. 8
    Dependence on the MUC1-C Oncoprotein in Non–Small Cell Lung Cancer Cells

    Dependence on the MUC1-C Oncoprotein in Non–Small Cell Lung Cancer Cells Tekijä Deepak Raina, Michio Kosugi, Rehan Ahmad, Govind Panchamoorthy, Hasan Rajabi, Maroof Alam, Takeshi Shimamura, Geoffrey I. Shapiro, Jeffrey G. Supko, Surender Kharbanda, Donald Küfe

    Julkaistu 2011
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  9. 9
    Resistance to Irreversible EGF Receptor Tyrosine Kinase Inhibitors through a Multistep Mechanism Involving the IGF1R Pathway

    Resistance to Irreversible EGF Receptor Tyrosine Kinase Inhibitors through a Multistep Mechanism Involving the IGF1R Pathway Tekijä Alexis B. Cortot, Claire E. Repellin, Takeshi Shimamura, Marzia Capelletti, Kreshnik Zejnullahu, Dalia Ercan, James G. Christensen, Kwok‐Kin Wong, Nathanael S. Gray, Pasi A. Jänne

    Julkaistu 2012
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  10. 10
    Chemokine (C-C Motif) Ligand 2 Mediates the Prometastatic Effect of Dysadherin in Human Breast Cancer Cells

    Chemokine (C-C Motif) Ligand 2 Mediates the Prometastatic Effect of Dysadherin in Human Breast Cancer Cells Tekijä Jeong‐Seok Nam, Mi‐Jin Kang, Adam M. Suchar, Takeshi Shimamura, Ethan A. Kohn, Aleksandra M. Michalowska, V. Craig Jordan, Setsuo Hirohashi, Lalage M. Wakefield

    Julkaistu 2006
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  11. 11
    Transcriptional Profiling Identifies Cyclin D1 as a Critical Downstream Effector of Mutant Epidermal Growth Factor Receptor Signaling

    Transcriptional Profiling Identifies Cyclin D1 as a Critical Downstream Effector of Mutant Epidermal Growth Factor Receptor Signaling Tekijä Susumu Kobayashi, Takeshi Shimamura, Stefano Monti, Ulrich Steidl, Christopher J. Hetherington, April M. Lowell, Todd R. Golub, Matthew Meyerson, Daniel G. Tenen, Geoffrey I. Shapiro, Balázs Halmos

    Julkaistu 2006
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  12. 12
    Combined EGFR/MET or EGFR/HSP90 Inhibition Is Effective in the Treatment of Lung Cancers Codriven by Mutant EGFR Containing T790M and MET

    Combined EGFR/MET or EGFR/HSP90 Inhibition Is Effective in the Treatment of Lung Cancers Codriven by Mutant EGFR Containing T790M and MET Tekijä Lu Xu, Eiki Kikuchi, Chunxiao Xu, Hiromichi Ebi, Dalia Ercan, Katherine A. Cheng, Robert F. Padera, Jeffrey A. Engelman, Pasi A. Jänne, Geoffrey I. Shapiro, Takeshi Shimamura, Kwok‐Kin Wong

    Julkaistu 2012
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  13. 13
    BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models

    BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models Tekijä D Li, Lauren Ambrogio, Takeshi Shimamura, Shigeto Kubo, Masaya Takahashi, Lucian R. Chirieac, Robert F. Padera, Geoffrey I. Shapiro, Anke Baum, Frank Himmelsbach, Wolfgang J. Rettig, Matthew Meyerson, Flavio Solca, Heidi Greulich, Kah Keng Wong

    Julkaistu 2008
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  14. 14
    Early Detection of Erlotinib Treatment Response in NSCLC by 3′-Deoxy-3′-[18F]-Fluoro-L-Thymidine ([18F]FLT) Positron Emission Tomography (PET)

    Early Detection of Erlotinib Treatment Response in NSCLC by 3′-Deoxy-3′-[18F]-Fluoro-L-Thymidine ([18F]FLT) Positron Emission Tomography (PET) Tekijä Roland T. Ullrich, Thomas Zander, Bernd Neumaier, Mirjam Koker, Takeshi Shimamura, Yannic Waerzeggers, Christa L. Borgman, Samir Tawadros, Hongfeng Li, Martin L. Sos, Heiko Backes, Geoffrey I. Shapiro, Jürgen Wolf, Andreas H. Jacobs, Roman K. Thomas, Alexandra Winkeler

    Julkaistu 2008
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  15. 15
    Intratumoral Heterogeneity in <i>EGFR</i>-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition

    Intratumoral Heterogeneity in <i>EGFR</i>-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition Tekijä Margaret Soucheray, Marzia Capelletti, Inés Pulido, Yanan Kuang, Cloud P. Paweletz, Jeffrey H. Becker, Eiki Kikuchi, Chunxiao Xu, Tarun B. Patel, Fátima Al‐Shahrour, Julián Carretero, Kwok‐Kin Wong, Pasi A. Jänne, Geoffrey I. Shapiro, Takeshi Shimamura

    Julkaistu 2015
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  16. 16
    PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data

    PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data Tekijä Elena Piñeiro-Yáñez, Miguel Reboiro‐Jato, Gonzalo Goméz-López, Javier Perales-Patón, Kevin Troulé, José Manuel Rodrı́guez, Héctor Tejero, Takeshi Shimamura, Pedro P. López‐Casas, Julián Carretero, Alfonso Valencia, Manuel Hidalgo, Daniel Glez‐Peña, Fátima Al‐Shahrour

    Julkaistu 2018
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  17. 17
    Somatic LKB1 Mutations Promote Cervical Cancer Progression

    Somatic LKB1 Mutations Promote Cervical Cancer Progression Tekijä Shana N. Wingo, Teresa D. Gallardo, Esra A. Akbay, Mei‐Chih Liang, Cristina M. Contreras, Todd Boren, Takeshi Shimamura, David S. Miller, Norman E. Sharpless, Nabeel Bardeesy, David J. Kwiatkowski, John O. Schorge, Kwok‐Kin Wong, Diego H. Castrillón

    Julkaistu 2009
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  18. 18
    Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer

    Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer Tekijä Takeshi Shimamura, Zhao Chen, Margaret Soucheray, Julián Carretero, Eiki Kikuchi, Jeremy H. Tchaicha, Yandi Gao, Katherine A. Cheng, Travis J. Cohoon, Jun Qi, Esra A. Akbay, Alec C. Kimmelman, Andrew L. Kung, James E. Bradner, Kwok‐Kin Wong

    Julkaistu 2013
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  19. 19
    LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

    LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma Tekijä Wenjin Liu, Kimberly B. Monahan, Adam D. Pfefferle, Takeshi Shimamura, Jessica A. Sorrentino, Keefe T. Chan, David W. Roadcap, David W. Ollila, Nancy E. Thomas, Diego H. Castrillón, C. Ryan Miller, Charles M. Perou, Kwok‐Kin Wong, James E. Bear, Norman E. Sharpless

    Julkaistu 2012
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  20. 20
    HIF1α and HIF2α independently activate SRC to promote melanoma metastases

    HIF1α and HIF2α independently activate SRC to promote melanoma metastases Tekijä Sara C. Hanna, Bhavani Krishnan, Sean T. Bailey, Stergios J. Moschos, Pei Fen Kuan, Takeshi Shimamura, Lukas D. Osborne, Marni B. Siegel, Lyn M. Duncan, E. Tim O’Brien, Richard Superfine, C. Ryan Miller, M. Celeste Simon, Kwok‐Kin Wong, William Y. Kim

    Julkaistu 2013
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