Resultats de la cerca - Steven J. Howe

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  1. 1
    Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

    Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer per Mustafa M. Munye, Aristides D. Tagalakis, Josephine L. Barnes, Rachel E. Brown, Robin J. McAnulty, Steven J. Howe, Stephen L. Hart

    Publicat 2016
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  2. 2
    Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells

    Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cel... per Fang Zhang, Susannah I. Thornhill, Steven J. Howe, Meera Ulaganathan, Axel Schambach, Joanna Sinclair, Christine Kinnon, H. Bobby Gaspar, Michael Antoniou, Adrian J. Thrasher

    Publicat 2007
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  3. 3
    Lentiviral vectors can be used for full-length dystrophin gene therapy

    Lentiviral vectors can be used for full-length dystrophin gene therapy per John R. Counsell, Zeinab Asgarian, Jinhong Meng, Verónica Ferrer, Conrad A. Vink, Steven J. Howe, Simon N. Waddington, Adrian J. Thrasher, Francesco Muntoni, Jennifer E. Morgan, Olivier Danos

    Publicat 2017
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  4. 4
    BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity

    BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity per Mustafa M. Munye, Amelia Shoemark, Robert A. Hirst, Juliette Delhove, Tyson V. Sharp, Tristan R. McKay, Christopher O’Callaghan, Deborah L. Baines, Steven J. Howe, Stephen L. Hart

    Publicat 2016
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  5. 5
    Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficiency

    Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficiency per Susannah I. Thornhill, Axel Schambach, Steven J. Howe, Meera Ulaganathan, Elke Grassman, David A. Williams, Bernhard Schiedlmeier, Neil J. Sebire, H. Bobby Gaspar, Christine Kinnon, Christopher Baum, Adrian J. Thrasher

    Publicat 2008
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  6. 6
    Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice

    Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice per Alex Langford-Smith, Fiona L. Wilkinson, Kia Langford‐Smith, Rebecca Holley, Ana Sergijenko, Steven J. Howe, William Bennett, Simon Jones, JE Wraith, Catherine L.R. Merry, Robert Wynn, Brian Bigger

    Publicat 2012
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  7. 7
    In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

    In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters per Suzanne M. K. Buckley, Juliette Delhove, Dany Perocheau, Rajvinder Karda, Rahimin Affandi Abdul Rahim, Steven J. Howe, Natalie J Ward, Mark A. Birrell, Maria G. Belvisi, Patrick Arbuthnot, Mark R. Johnson, Simon N. Waddington, Tristan R. McKay

    Publicat 2015
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  8. 8
    Failure of SCID-X1 gene therapy in older patients

    Failure of SCID-X1 gene therapy in older patients per Adrian J. Thrasher, Salima Hacein‐Bey‐Abina, H. Bobby Gaspar, Stéphane Blanche, E. Graham Davies, Kathryn L. Parsley, Kimberly Gilmour, Douglas King, Steven J. Howe, Joanna Sinclair, Christophe Hue, Frédérique Carlier, Christof von Kalle, Geneviève de Saint Basile, Françoise Le Deist, Alain Fischer, Marina Cavazzana

    Publicat 2005
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  9. 9
    Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues

    Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues per Cynthia C. Bartholomae, Anne I.J. Arens, Kamaljit S. Balaggan, Rafael J. Yáñez‐Muñoz, Eugenio Montini, Steven J. Howe, Anna Paruzynski, Bernhard Korn, Jens Uwe Appelt, Angus MacNeil, Daniela Cesana, Ulrich Abel, Hanno Glimm, Luigi Naldini, Robin R. Ali, Adrian J. Thrasher, Christof von Kalle, Manfred Schmidt

    Publicat 2011
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  10. 10
    Vps33b is crucial for structural and functional hepatocyte polarity

    Vps33b is crucial for structural and functional hepatocyte polarity per Joanna Hanley, Dipok Kumar Dhar, Francesca Mazzacuva, Rebeca Fiadeiro, Jemima J. Burden, Anne-Marie Lyne, Holly Smith, Anna Straatman-Iwanowska, Blerida Banushi, Alex Virasami, Kevin Mills, Frédéric P. Lemaigre, A. S. Knisely, Steven J. Howe, Neil J. Sebire, Simon N. Waddington, Coen C. Paulusma, Peter T. Clayton, Paul Gissen

    Publicat 2017
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  11. 11
    Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

    Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo per Kerstin Schwarzwaelder, Steven J. Howe, Manfred Schmidt, Martijn H. Brugman, Annette Deichmann, Hanno Glimm, Sonja Schmidt, Claudia Prinz, Manuela Wissler, Douglas King, Fang Zhang, Kathryn L. Parsley, Kimberly Gilmour, Joanna Sinclair, Jinhua Bayford, Rachel Peraj, Karin Pike‐Overzet, Frank J. T. Staal, Dick de Ridder, Christine Kinnon, Ulrich Abel, Gerard Wagemaker, H. Bobby Gaspar, Adrian J. Thrasher, Christof von Kalle

    Publicat 2007
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  12. 12
    Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

    Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle per Carys Johnson, Matthew Williams, Kendig Sham, Serena Belluschi, Wenjuan Ma, Xiaonan Wang, Winnie Lau, Kerstin B. Kaufmann, Gabriela Krivdova, Emily F. Calderbank, Nicole Mende, Jessica McLeod, Giovanna Mantica, Juan Li, Charlotte Grey-Wilson, Michael Drakopoulos, Shaaezmeen Basheer, Shubhankar Sinha, Evangelia Diamanti, Christina Basford, Nicola K. Wilson, Steven J. Howe, John E. Dick, Berthold Göttgens, Anthony R. Green, Natalie Francis, Elisa Laurenti

    Publicat 2024
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  13. 13
    Site- and allele-specific polycomb dysregulation in T-cell leukaemia

    Site- and allele-specific polycomb dysregulation in T-cell leukaemia per Jean‐Marc Navarro, Aurore Touzart, Lydie Pradel, Marie Loosveld, Myriam Koubi, Romain Fenouil, Sandrine Le Noir, Muhammad Ahmad Maqbool, Ester Morgado, Claude Grégoire, Sébastien Jaeger, Émilie Mamessier, Charles P. Pignon, Salima Hacein‐Bey‐Abina, Bernard Malissen, Marta Gut, Marta Gut, Hervé Dombret, Elizabeth Macintyre, Steven J. Howe, H. Bobby Gaspar, Adrian J. Thrasher, Norbert Ifrah, Dominique Payet‐Bornet, Estelle Duprez, Jean‐Christophe Andrau, Vahid Asnafi, Bertrand Nadel

    Publicat 2015
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  14. 14
    Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

    Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients per Steven J. Howe, Marc R. Mansour, Kerstin Schwarzwaelder, Cynthia C. Bartholomae, Michael Hubank, Helena Kempski, Martijn H. Brugman, Karin Pike‐Overzet, S Chatters, Dick de Ridder, Kimberly Gilmour, Stuart Adams, Susannah I. Thornhill, Kathryn L. Parsley, Frank J. T. Staal, Rosemary E. Gale, David C. Linch, Jinhua Bayford, Lucie Brown, Michelle Quaye, Christine Kinnon, Philip Ancliff, David Webb, Manfred Schmidt, Christof von Kalle, H. Bobby Gaspar, Adrian J. Thrasher

    Publicat 2008
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  15. 15
    Insertion Sites in Engrafted Cells Cluster Within a Limited Repertoire of Genomic Areas After Gammaretroviral Vector Gene Therapy

    Insertion Sites in Engrafted Cells Cluster Within a Limited Repertoire of Genomic Areas After Gammaretroviral Vector Gene Therapy per Annette Deichmann, Martijn H. Brugman, Cynthia C. Bartholomae, Kerstin Schwarzwaelder, Monique M.A. Verstegen, Steven J. Howe, Anne I.J. Arens, Marion Ott, Dieter Hoelzer, Reinhard Seger, Manuel Grez, Salima Hacein‐Bey‐Abina, Marina Cavazzana, Alain Fischer, Anna Paruzynski, Richard Gabriel, Hanno Glimm, Ulrich Abel, Claudia Cattoglio, Fulvio Mavilio, Barbara Cassani, Alessandro Aiuti, Cynthia E. Dunbar, Christopher Baum, H. Bobby Gaspar, Adrian J. Thrasher, Christof von Kalle, Manfred Schmidt, Gerard Wagemaker

    Publicat 2011
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  16. 16
    Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

    Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy per Annette Deichmann, Salima Hacein‐Bey‐Abina, Manfred Schmidt, Alexandrine Garrigue, Martijn H. Brugman, Jingqiong Hu, Hanno Glimm, Gàbor Gyapay, Bernard Prum, Christopher C. Fraser, Nicolas Fischer, Kerstin Schwarzwaelder, Maria-Luise Siegler, Dick de Ridder, Karin Pike‐Overzet, Steven J. Howe, Adrian J. Thrasher, Gerard Wagemaker, Ulrich Abel, Frank J. T. Staal, Éric Delabesse, Jean‐Luc Villeval, Bruce J. Aronow, Christophe Hue, Claudia Prinz, Manuela Wissler, Chuck Klanke, Jean Weissenbach, Ian E. Alexander, Alain Fischer, Christof von Kalle, Marina Cavazzana

    Publicat 2007
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