Kết quả tìm kiếm - Stephen C. Pak
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C. elegans in high-throughput drug discovery Bằng Linda P. O’Reilly, Cliff J. Luke, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak
Được phát hành 2013Revisão -
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Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis Bằng Gary A. Silverman, James C. Whisstock, David J. Askew, Stephen C. Pak, Cliff J. Luke, Sule Çataltepe, James A. Irving, Phillip I. Bird
Được phát hành 2004Revisão -
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Serpins Flex Their Muscle Bằng James C. Whisstock, Gary A. Silverman, Phillip I. Bird, Stephen Bottomley, Dion Kaiserman, Cliff J. Luke, Stephen C. Pak, Jean-Marc Reichhart, James A. Huntington
Được phát hành 2010Revisão -
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Serpins Flex Their Muscle Bằng Gary A. Silverman, James C. Whisstock, Stephen Bottomley, James A. Huntington, Dion Kaiserman, Cliff J. Luke, Stephen C. Pak, Jean-Marc Reichhart, Phillip I. Bird
Được phát hành 2010Revisão -
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Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency Bằng Jie Li, Stephen C. Pak, Linda P. O’Reilly, Joshua A. Benson, Yán Wāng, Tunda Hidvegi, Pamela Hale, Christine Dippold, Michael Ewing, Gary A. Silverman, David H. Perlmutter
Được phát hành 2014Artigo -
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Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision Bằng Dustin Baldridge, Michael F. Wangler, Angela N. Bowman, Shinya Yamamoto, Tim Schedl, Stephen C. Pak, John H. Postlethwait, Jimann Shin, Lilianna Solnica‐Krezel, Hugo J. Bellen, Monte Westerfield
Được phát hành 2021Artigo -
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A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency Bằng Linda P. O’Reilly, Olivia S. Long, Murat Can Çobanoğlu, Joshua A. Benson, Cliff J. Luke, Mark T. Miedel, Pamela Hale, David H. Perlmutter, İvet Bahar, Gary A. Silverman, Stephen C. Pak
Được phát hành 2014Artigo -
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Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z Bằng Sager J. Gosai, Joon Hyeok Kwak, Cliff J. Luke, Olivia S. Long, Dale E. King, Kevin J. Kovatch, Paul A. Johnston, Tong Ying Shun, John S. Lazo, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak
Được phát hành 2010Artigo -
11
An Intracellular Serpin Regulates Necrosis by Inhibiting the Induction and Sequelae of Lysosomal Injury Bằng Cliff J. Luke, Stephen C. Pak, Yuko S. Askew, Terra L. Naviglia, David J. Askew, Shila M. Nobar, Anne C. Vetica, Olivia S. Long, Simon C. Watkins, Donna B. Stolz, Robert Barstead, Gary Moulder, Dieter Brömme, Gary A. Silverman
Được phát hành 2007Artigo -
12
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy Bằng Young Mi Oh, Seong Won Lee, Woo Kyung Kim, Shawei Chen, Victoria A. Church, K. Lynn Cates, Tiandao Li, Bo Zhang, Roland E. Dolle, Sonika Dahiya, Stephen C. Pak, Gary A. Silverman, David H. Perlmutter, Andrew S. Yoo
Được phát hành 2022Artigo -
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A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover Bằng Olivia S. Long, Joshua A. Benson, Joon Hyeok Kwak, Cliff J. Luke, Sager J. Gosai, Linda P. O’Reilly, Yán Wāng, Jie Li, Anne C. Vetica, Mark T. Miedel, Donna B. Stolz, Simon C. Watkins, Stephan Züchner, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak
Được phát hành 2014Artigo -
14
Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer Bằng Stephanie Markovina, Songyan Wang, Lauren E. Henke, Cliff J. Luke, Stephen C. Pak, T.A. DeWees, John D. Pfeifer, Julie K. Schwarz, Weijun Liu, Shuai Chen, David G. Mutch, Xiaowei Wang, Matthew A. Powell, Barry A. Siegel, Farrokh Dehdashti, Gary A. Silverman, Perry W. Grigsby
Được phát hành 2017Artigo -
15
Sequence variants in HECTD1 result in a variable neurodevelopmental disorder Bằng Gazelle Zerafati‐Jahromi, Elias Oxman, Hieu D. Hoang, Wu‐Lin Charng, Tanvitha Kotla, Weimin Yuan, Kenichi Ishibashi, Sonia Sebaoui, Kathryn Luedtke, Bryce Winrow, Rebecca Ganetzky, Anna Ruiz, Carmen Manso-Basúz, Nino Spataro, Pekka Kannus, Taryn Athey, Christina Peroutka, Caitlin Barnes, Richard Sidlow, George Anadiotis, Kari Magnussen, Irene Valenzuela, Alejandro Moles‐Fernández, Seth Berger, Christina Grant, Éric Vilain, Gudny A. Arnadottir, Patrick Sulem, Telma Sulem, Kāri Stefánsson, Shavonne L. Massey, Natalie Ginn, Annapurna Poduri, Alissa M. D’Gama, Rozalia Valentine, Sara Trowbridge, Chaya N. Murali, Rachel Franciskovich, Thi Hai Yen Tran, Bryn D. Webb, Kim M. Keppler‐Noreuil, April Hall, Bobbi McGivern, Kristin G. Monaghan, Maria J. Guillen Sacoto, Dustin Baldridge, Gary A. Silverman, Sonika Dahiya, Tychele N. Turner, Tim Schedl, Jackie D. Corbin, Stephen C. Pak, Irene E. Zohn, Christina A. Gurnett
Được phát hành 2025Artigo -
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An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids Bằng Sacha Ferdinandusse, Kirsty McWalter, Heleen te Brinke, Lodewijk IJlst, Petra M. Mooijer, Jos P.N. Ruiter, A. E. M. van Lint, Mia L. Pras‐Raves, Eric Wever, Francisca Millan, María J. Guillen Sacoto, Amber Begtrup, Mark A. Tarnopolsky, Lauren Brady, Roger L. Ladda, Susan L. Sell, C. Nowak, Jessica Douglas, Cuixia Tian, Elizabeth Ulm, Seth J. Perlman, Arlene V. Drack, Karen Chong, Nicole Martin, Jennifer Brault, Elly Brokamp, Camilo Toro, William A. Gahl, Ellen F. Macnamara, Lynne A. Wolfe, Mercedes E. Alejandro, Mahshid S. Azamian, Carlos A. Bacino, Ashok Balasubramanyam, Lindsay C. Burrage, Hsiao‐Tuan Chao, Gary Clark, William J. Craigen, Hongzheng Dai, Shweta U. Dhar, Lisa Emrick, Alica M. Goldman, Neil A. Hanchard, Fariha Jamal, Lefkothea Karaviti, Seema R. Lalani, Brendan Lee, Richard A. Lewis, Ronit Marom, Paolo Moretti, David R. Murdock, Sarah K. Nicholas, James P. Orengo, Jennifer E. Posey, Lorraine Potocki, Jill A. Rosenfeld, Susan L. Samson, Daryl A. Scott, Alyssa A. Tran, Tiphanie P. Vogel, Michael F. Wangler, Shinya Yamamoto, Christine M. Eng, Pengfei Liu, Patricia A. Ward, Edward M. Behrens, Matthew A. Deardorff, Marni J. Falk, Kelly Hassey, Kathleen Sullivan, Adeline Vanderver, David B. Goldstein, Heidi Cope, Allyn McConkie‐Rosell, Kelly Schoch, Vandana Shashi, Edward C. Smith, Rebecca C. Spillmann, Jennifer A. Sullivan, Queenie K.‐G. Tan, Sophie Nicole, Pankaj B. Agrawal, Alan H. Beggs, Gerard T. Berry, Lauren C. Briere, Laurel A. Cobban, Matthew Coggins, Cynthia M. Cooper, Elizabeth L. Fieg, Frances A. High, Ingrid A. Holm, Susan Korrick, Joel B. Krier, Sharyn A. Lincoln, Joseph Loscalzo, Richard L. Maas, Calum A. MacRae, J. Carl Pallais, Stephen C. Pak, Lance H. Rodan
Được phát hành 2020Artigo -
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<i>SPTSSA</i> variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia Bằng Siddharth Srivastava, Hagar Mor Shaked, Kenneth Gable, Sita D. Gupta, Xueyang Pan, Niranjanakumari Somashekarappa, Gongshe Han, Payam Mohassel, Marc Gotkine, Elizabeth Doney, Paula Goldenberg, Queenie K.‐G. Tan, Yi Gong, Benjamin P. Kleinstiver, Brian Wishart, Heidi Cope, Cláudia Brito Pires, Hannah E. Stutzman, Rebecca C. Spillmann, Mercedes E. Alejandro, Mahshid S. Azamian, Carlos A. Bacino, Ashok Balasubramanyam, Lindsay C. Burrage, Hsiao‐Tuan Chao, Gary Clark, William J. Craigen, Hongzheng Dai, Shweta U. Dhar, Lisa Emrick, Alica M. Goldman, Neil A. Hanchard, Fariha Jamal, Lefkothea Karaviti, Seema R. Lalani, Brendan Lee, Richard A. Lewis, Ronit Marom, Paolo Moretti, David R. Murdock, Sarah K. Nicholas, James P. Orengo, Jennifer E. Posey, Lorraine Potocki, Jill A. Rosenfeld, Susan L. Samson, Daryl A. Scott, Alyssa A. Tran, Tiphanie P. Vogel, Michael F. Wangler, Shinya Yamamoto, Christine M. Eng, Pengfei Liu, Patricia A. Ward, Edward M. Behrens, Matthew A. Deardorff, Marni J. Falk, Kelly Hassey, Kathleen E. Sullivan, Adeline Vanderver, David B. Goldstein, Heidi Cope, Allyn McConkie‐Rosell, Kelly Schoch, Vandana Shashi, Edward C. Smith, Rebecca C. Spillmann, Jennifer A. Sullivan, Queenie K-G Tan, Sophie Nicole, Pankaj B. Agrawal, Alan H. Beggs, Gerard T. Berry, Lauren C. Briere, Laurel A. Cobban, Matthew Coggins, Cynthia M. Cooper, Elizabeth L. Fieg, Frances A. High, Ingrid A. Holm, Susan Korrick, Joel B. Krier, Sharyn A. Lincoln, Joseph Loscalzo, Richard L. Maas, Calum A. MacRae, J. Carl Pallais, Stephen C. Pak, Lance H. Rodan, Edwin K. Silverman, Joan M. Stoler, David A. Sweetser, Melissa Walker, Chris A. Walsh, Cecilia Esteves, Emily G. Kelley, Isaac S. Kohane, Kimberly LeBlanc, Alexa T. McCray, Anna Nagy
Được phát hành 2023Artigo
Công cụ tìm kiếm:
Các môn học liên quan
Biology
Gene
Genetics
Biochemistry
Cell biology
Medicine
Computational biology
Serpin
Bioinformatics
Caenorhabditis elegans
Drug discovery
Internal medicine
Apoptosis
Chemistry
Disease
Enzyme
High-throughput screening
Pharmacology
Phenotype
Proteolysis
Autophagy
Computer science
Drug
Electrical engineering
Endoplasmic reticulum
Engineering
Genome
Intracellular
Model organism
Mutant