نتائج البحث - Stephen C. Pak

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  1. 1
    C. elegans in high-throughput drug discovery

    C. elegans in high-throughput drug discovery حسب Linda P. O’Reilly, Cliff J. Luke, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak

    منشور في 2013
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  2. 2
    Quantitative assessment of cell fate decision between autophagy and apoptosis

    Quantitative assessment of cell fate decision between autophagy and apoptosis حسب Bing Liu, Zoltán N. Oltvai, Hülya Bayır, Gary A. Silverman, Stephen C. Pak, David H. Perlmutter, İvet Bahar

    منشور في 2017
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    Artigo
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  3. 3
    Modeling Molecular and Cellular Aspects of Human Disease Using the Nematode Caenorhabditis elegans

    Modeling Molecular and Cellular Aspects of Human Disease Using the Nematode Caenorhabditis elegans حسب Gary A. Silverman, Cliff J. Luke, Sangeeta Rani Bhatia, Olivia S. Long, Anne C. Vetica, David H. Perlmutter, Stephen C. Pak

    منشور في 2008
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  4. 4
    Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis

    Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis حسب Gary A. Silverman, James C. Whisstock, David J. Askew, Stephen C. Pak, Cliff J. Luke, Sule Çataltepe, James A. Irving, Phillip I. Bird

    منشور في 2004
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  5. 5
    Serpins Flex Their Muscle

    Serpins Flex Their Muscle حسب James C. Whisstock, Gary A. Silverman, Phillip I. Bird, Stephen Bottomley, Dion Kaiserman, Cliff J. Luke, Stephen C. Pak, Jean-Marc Reichhart, James A. Huntington

    منشور في 2010
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  6. 6
    Serpins Flex Their Muscle

    Serpins Flex Their Muscle حسب Gary A. Silverman, James C. Whisstock, Stephen Bottomley, James A. Huntington, Dion Kaiserman, Cliff J. Luke, Stephen C. Pak, Jean-Marc Reichhart, Phillip I. Bird

    منشور في 2010
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  7. 7
    Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency

    Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency حسب Jie Li, Stephen C. Pak, Linda P. O’Reilly, Joshua A. Benson, Yán Wāng, Tunda Hidvegi, Pamela Hale, Christine Dippold, Michael Ewing, Gary A. Silverman, David H. Perlmutter

    منشور في 2014
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  8. 8
    Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision

    Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision حسب Dustin Baldridge, Michael F. Wangler, Angela N. Bowman, Shinya Yamamoto, Tim Schedl, Stephen C. Pak, John H. Postlethwait, Jimann Shin, Lilianna Solnica‐Krezel, Hugo J. Bellen, Monte Westerfield

    منشور في 2021
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  9. 9
    A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency

    A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency حسب Linda P. O’Reilly, Olivia S. Long, Murat Can Çobanoğlu, Joshua A. Benson, Cliff J. Luke, Mark T. Miedel, Pamela Hale, David H. Perlmutter, İvet Bahar, Gary A. Silverman, Stephen C. Pak

    منشور في 2014
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  10. 10
    Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z

    Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z حسب Sager J. Gosai, Joon Hyeok Kwak, Cliff J. Luke, Olivia S. Long, Dale E. King, Kevin J. Kovatch, Paul A. Johnston, Tong Ying Shun, John S. Lazo, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak

    منشور في 2010
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  11. 11
    An Intracellular Serpin Regulates Necrosis by Inhibiting the Induction and Sequelae of Lysosomal Injury

    An Intracellular Serpin Regulates Necrosis by Inhibiting the Induction and Sequelae of Lysosomal Injury حسب Cliff J. Luke, Stephen C. Pak, Yuko S. Askew, Terra L. Naviglia, David J. Askew, Shila M. Nobar, Anne C. Vetica, Olivia S. Long, Simon C. Watkins, Donna B. Stolz, Robert Barstead, Gary Moulder, Dieter Brömme, Gary A. Silverman

    منشور في 2007
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  12. 12
    Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy

    Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy حسب Young Mi Oh, Seong Won Lee, Woo Kyung Kim, Shawei Chen, Victoria A. Church, K. Lynn Cates, Tiandao Li, Bo Zhang, Roland E. Dolle, Sonika Dahiya, Stephen C. Pak, Gary A. Silverman, David H. Perlmutter, Andrew S. Yoo

    منشور في 2022
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  13. 13
    A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover

    A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover حسب Olivia S. Long, Joshua A. Benson, Joon Hyeok Kwak, Cliff J. Luke, Sager J. Gosai, Linda P. O’Reilly, Yán Wāng, Jie Li, Anne C. Vetica, Mark T. Miedel, Donna B. Stolz, Simon C. Watkins, Stephan Züchner, David H. Perlmutter, Gary A. Silverman, Stephen C. Pak

    منشور في 2014
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    Artigo
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  14. 14
    Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer

    Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer حسب Stephanie Markovina, Songyan Wang, Lauren E. Henke, Cliff J. Luke, Stephen C. Pak, T.A. DeWees, John D. Pfeifer, Julie K. Schwarz, Weijun Liu, Shuai Chen, David G. Mutch, Xiaowei Wang, Matthew A. Powell, Barry A. Siegel, Farrokh Dehdashti, Gary A. Silverman, Perry W. Grigsby

    منشور في 2017
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  15. 15
    Sequence variants in HECTD1 result in a variable neurodevelopmental disorder

    Sequence variants in HECTD1 result in a variable neurodevelopmental disorder حسب Gazelle Zerafati‐Jahromi, Elias Oxman, Hieu D. Hoang, Wu‐Lin Charng, Tanvitha Kotla, Weimin Yuan, Kenichi Ishibashi, Sonia Sebaoui, Kathryn Luedtke, Bryce Winrow, Rebecca Ganetzky, Anna Ruiz, Carmen Manso-Basúz, Nino Spataro, Pekka Kannus, Taryn Athey, Christina Peroutka, Caitlin Barnes, Richard Sidlow, George Anadiotis, Kari Magnussen, Irene Valenzuela, Alejandro Moles‐Fernández, Seth Berger, Christina Grant, Éric Vilain, Gudny A. Arnadottir, Patrick Sulem, Telma Sulem, Kāri Stefánsson, Shavonne L. Massey, Natalie Ginn, Annapurna Poduri, Alissa M. D’Gama, Rozalia Valentine, Sara Trowbridge, Chaya N. Murali, Rachel Franciskovich, Thi Hai Yen Tran, Bryn D. Webb, Kim M. Keppler‐Noreuil, April Hall, Bobbi McGivern, Kristin G. Monaghan, Maria J. Guillen Sacoto, Dustin Baldridge, Gary A. Silverman, Sonika Dahiya, Tychele N. Turner, Tim Schedl, Jackie D. Corbin, Stephen C. Pak, Irene E. Zohn, Christina A. Gurnett

    منشور في 2025
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  16. 16
    An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

    An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids حسب Sacha Ferdinandusse, Kirsty McWalter, Heleen te Brinke, Lodewijk IJlst, Petra M. Mooijer, Jos P.N. Ruiter, A. E. M. van Lint, Mia L. Pras‐Raves, Eric Wever, Francisca Millan, María J. Guillen Sacoto, Amber Begtrup, Mark A. Tarnopolsky, Lauren Brady, Roger L. Ladda, Susan L. Sell, C. Nowak, Jessica Douglas, Cuixia Tian, Elizabeth Ulm, Seth J. Perlman, Arlene V. Drack, Karen Chong, Nicole Martin, Jennifer Brault, Elly Brokamp, Camilo Toro, William A. Gahl, Ellen F. Macnamara, Lynne A. Wolfe, Mercedes E. Alejandro, Mahshid S. Azamian, Carlos A. Bacino, Ashok Balasubramanyam, Lindsay C. Burrage, Hsiao‐Tuan Chao, Gary Clark, William J. Craigen, Hongzheng Dai, Shweta U. Dhar, Lisa Emrick, Alica M. Goldman, Neil A. Hanchard, Fariha Jamal, Lefkothea Karaviti, Seema R. Lalani, Brendan Lee, Richard A. Lewis, Ronit Marom, Paolo Moretti, David R. Murdock, Sarah K. Nicholas, James P. Orengo, Jennifer E. Posey, Lorraine Potocki, Jill A. Rosenfeld, Susan L. Samson, Daryl A. Scott, Alyssa A. Tran, Tiphanie P. Vogel, Michael F. Wangler, Shinya Yamamoto, Christine M. Eng, Pengfei Liu, Patricia A. Ward, Edward M. Behrens, Matthew A. Deardorff, Marni J. Falk, Kelly Hassey, Kathleen Sullivan, Adeline Vanderver, David B. Goldstein, Heidi Cope, Allyn McConkie‐Rosell, Kelly Schoch, Vandana Shashi, Edward C. Smith, Rebecca C. Spillmann, Jennifer A. Sullivan, Queenie K.‐G. Tan, Sophie Nicole, Pankaj B. Agrawal, Alan H. Beggs, Gerard T. Berry, Lauren C. Briere, Laurel A. Cobban, Matthew Coggins, Cynthia M. Cooper, Elizabeth L. Fieg, Frances A. High, Ingrid A. Holm, Susan Korrick, Joel B. Krier, Sharyn A. Lincoln, Joseph Loscalzo, Richard L. Maas, Calum A. MacRae, J. Carl Pallais, Stephen C. Pak, Lance H. Rodan

    منشور في 2020
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  17. 17
    <i>SPTSSA</i> variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia

    <i>SPTSSA</i> variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia حسب Siddharth Srivastava, Hagar Mor Shaked, Kenneth Gable, Sita D. Gupta, Xueyang Pan, Niranjanakumari Somashekarappa, Gongshe Han, Payam Mohassel, Marc Gotkine, Elizabeth Doney, Paula Goldenberg, Queenie K.‐G. Tan, Yi Gong, Benjamin P. Kleinstiver, Brian Wishart, Heidi Cope, Cláudia Brito Pires, Hannah E. Stutzman, Rebecca C. Spillmann, Mercedes E. Alejandro, Mahshid S. Azamian, Carlos A. Bacino, Ashok Balasubramanyam, Lindsay C. Burrage, Hsiao‐Tuan Chao, Gary Clark, William J. Craigen, Hongzheng Dai, Shweta U. Dhar, Lisa Emrick, Alica M. Goldman, Neil A. Hanchard, Fariha Jamal, Lefkothea Karaviti, Seema R. Lalani, Brendan Lee, Richard A. Lewis, Ronit Marom, Paolo Moretti, David R. Murdock, Sarah K. Nicholas, James P. Orengo, Jennifer E. Posey, Lorraine Potocki, Jill A. Rosenfeld, Susan L. Samson, Daryl A. Scott, Alyssa A. Tran, Tiphanie P. Vogel, Michael F. Wangler, Shinya Yamamoto, Christine M. Eng, Pengfei Liu, Patricia A. Ward, Edward M. Behrens, Matthew A. Deardorff, Marni J. Falk, Kelly Hassey, Kathleen E. Sullivan, Adeline Vanderver, David B. Goldstein, Heidi Cope, Allyn McConkie‐Rosell, Kelly Schoch, Vandana Shashi, Edward C. Smith, Rebecca C. Spillmann, Jennifer A. Sullivan, Queenie K-G Tan, Sophie Nicole, Pankaj B. Agrawal, Alan H. Beggs, Gerard T. Berry, Lauren C. Briere, Laurel A. Cobban, Matthew Coggins, Cynthia M. Cooper, Elizabeth L. Fieg, Frances A. High, Ingrid A. Holm, Susan Korrick, Joel B. Krier, Sharyn A. Lincoln, Joseph Loscalzo, Richard L. Maas, Calum A. MacRae, J. Carl Pallais, Stephen C. Pak, Lance H. Rodan, Edwin K. Silverman, Joan M. Stoler, David A. Sweetser, Melissa Walker, Chris A. Walsh, Cecilia Esteves, Emily G. Kelley, Isaac S. Kohane, Kimberly LeBlanc, Alexa T. McCray, Anna Nagy

    منشور في 2023
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