Хайлтын үр дүнгүүд - Srinivasaraghavan Kannan

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  1. 1
    Folding of a DNA Hairpin Loop Structure in Explicit Solvent Using Replica-Exchange Molecular Dynamics Simulations

    Folding of a DNA Hairpin Loop Structure in Explicit Solvent Using Replica-Exchange Molecular Dynamics Simulations -н Srinivasaraghavan Kannan, Martin Zacharias

    Хэвлэсэн 2007
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    Artigo
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  2. 2
    Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket

    Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket -н Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma

    Хэвлэсэн 2018
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  3. 3
    AKT signaling in ERBB2-amplified breast cancer

    AKT signaling in ERBB2-amplified breast cancer -н F. Javier Carmona, Filippo Montemurro, Srinivasaraghavan Kannan, Valentina Rossi, Chandra Verma, José Baselga, Maurizio Scaltriti

    Хэвлэсэн 2015
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  4. 4
    Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer

    Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast... -н Denis M. Collins, Neil T. Conlon, Srinivasaraghavan Kannan, Chandra Verma, Lisa D. Eli, Alshad S. Lalani, John Crown

    Хэвлэсэн 2019
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  5. 5
    Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules

    Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional... -н Sangith, Nikhil, Srinivasaraghavan, Kannan, Sahu, Indrajit, Desai, Ankita, Medipally, Spandana, Somavarappu, Arun Kumar, Verma, Chandra, Venkatraman, Prasanna

    Хэвлэсэн 2014
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  6. 6
    Corrigendum to “Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules” [FEBS Open Bio 4 (2014) 571–583]

    Corrigendum to “Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of puta... -н Sangith, Nikhil, Srinivasaraghavan, Kannan, Sahu, Indrajit, Desai, Ankita, Medipally, Spandana, Somavarappu, Arun Kumar, Verma, Chandra, Venkatraman, Prasanna

    Хэвлэсэн 2015
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  7. 7
    Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513

    Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513 -н Wong, Yee Hwa, Kumar, Akshita, Liew, Chong Wai, Tharakaraman, Kannan, Srinivasaraghavan, Kannan, Sasisekharan, Ram, Verma, Chandra, Lescar, Julien

    Хэвлэсэн 2018
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  8. 8
    Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket

    Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket -н Mohan R. Pradhan, Jia Wei Siau, Srinivasaraghavan Kannan, Minh N. Nguyen, Zohra Ouaray, Chee Keong Kwoh, David P. Lane, Farid J. Ghadessy, Chandra Verma

    Хэвлэсэн 2019
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    Artigo
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  9. 9
    A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

    A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing -н Conrad V. Simoben, Dina Robaa, Alokta Chakrabarti, Matthias Schmidt, Martin Marek, Julien Lancelot, Srinivasaraghavan Kannan, Jelena Melesina, T.B. Shaik, Raymond J. Pierce, Christophe Romier, Manfred Jung, Wolfgang Sippl

    Хэвлэсэн 2018
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  10. 10
    PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition

    PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition -н Pau Castel, Haley Ellis, Ružica Bago, Eneda Toska, Pedram Razavi, F. Javier Carmona, Srinivasaraghavan Kannan, Chandra Verma, Maura N. Dickler, Sarat Chandarlapaty, Edi Brogi, Dario R. Alessi, José Baselga, Maurizio Scaltriti

    Хэвлэсэн 2016
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  11. 11
    Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni

    Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni -н Martin Marek, Srinivasaraghavan Kannan, Alexander‐Thomas Hauser, Marina de Moraes Mourão, Stéphanie Caby, Vincent Cura, Diana A. Stolfa, Matthias Schmidt, Julien Lancelot, Luiza F Andrade, Jean‐Paul Renaud, Guilherme Oliveira, Wolfgang Sippl, Manfred Jung, J. Cavarelli, Raymond J. Pierce, Christophe Romier

    Хэвлэсэн 2013
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  12. 12
    PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression

    PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression -н Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn W.Q. Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Y. Lim, Jane Jia Hui Lee, Anders J. Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S. Verma, Yvonne Tay, Daniel S.W. Tan, Wai Leong Tam

    Хэвлэсэн 2024
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  13. 13
    Responsiveness of different MET tumour alterations to type I and type II MET inhibitors

    Responsiveness of different MET tumour alterations to type I and type II MET inhibitors -н Yonina R. Murciano‐Goroff, Valentina Foglizzo, Jason Chang, Natasha Rekhtman, Ann Elizabeth Sisk, Jamie Gibson, Lia Judka, Karen R. Clemens, Paola Roa, Shaza Ahmed, Nicole Virginia Bremer, Courtney Lynn Binaco, Sherifah Kemigisha Muzungu, Estelamari Rodríguez, Madeline Merrill, Erica Sgroe, Matteo Repetto, Zsofia K. Stadler, Michael F. Berger, Helena A. Yu, Eneda Toska, Srinivasaraghavan Kannan, Chandra Verma, Alexander Drilon, Emiliano Cocco

    Хэвлэсэн 2025
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  14. 14
    FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer

    FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer -н Amaia Arruabarrena-Aristorena, Jesper L.V. Mååg, Srushti Kittane, Yanyan Cai, Wouter R. Karthaus, Erik Ladewig, Jane Park, Srinivasaraghavan Kannan, Lorenzo Ferrando, Emiliano Cocco, Sik Yin Ho, Daisylyn Senna Tan, Mirna Sallaku, Fan Wu, Barbara Acevedo, Pier Selenica, Dara S. Ross, Matthew D. Witkin, Charles L. Sawyers, Jorge S. Reis‐Filho, Chandra Verma, Ralf Jauch, Richard P. Koche, José Baselga, Pedram Razavi, Eneda Toska, Maurizio Scaltriti

    Хэвлэсэн 2020
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  15. 15
    Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists

    Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists -н Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu‐Chi Juang, Lan Ge, Pietro G. A. Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra Verma, David P. Lane, Tomi K. Sawyer, R. M. Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J. Brown, Charles W. Johannes, Anthony W. Partridge

    Хэвлэсэн 2024
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  16. 16
    Macrocyclization of an all-<scp>d</scp> linear α-helical peptide imparts cellular permeability

    Macrocyclization of an all-<scp>d</scp> linear α-helical peptide imparts cellular permeability -н Srinivasaraghavan Kannan, Pietro G. A. Aronica, Simon Ng, Dawn Thean Gek Lian, Yuri Frosi, Sharon Chee, Shimin Jiang, Tsz Ying Yuen, Ahmad Sadruddin, Hung Yi Kristal Kaan, Arun Chandramohan, Jin Huei Wong, Yaw Sing Tan, Zi Wei Chang, Fernando J. Ferrer‐Gago, Prakash Arumugam, Yi Han, Shiying Chen, Laurent Rénia, Christopher J. Brown, Charles W. Johannes, Brian Henry, David P. Lane, Tomi K. Sawyer, Chandra Verma, Anthony W. Partridge

    Хэвлэсэн 2020
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  17. 17
    TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors

    TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors -н Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M. Schram, Helen Won, Sophie Shifman, Amanda Kulick, Laura Baldino, Eneda Toska, Amaia Arruabarrena-Aristorena, Srushti Kittane, Fan Wu, Yanyan Cai, Sabrina Arena, Benedetta Mussolin, Ram Kannan, Neil Vasan, Alexander N. Gorelick, Michael F. Berger, Ofra Novoplansky, Sankar Jagadeeshan, Yi Liao, Uwe Rix, Sandra Misale, Barry S. Taylor, Alberto Bardelli, Jaclyn F. Hechtman, David M. Hyman, Moshe Elkabets, Elisa de Stanchina, Chandra Verma, Andrea Ventura, Alexander Drilon, Maurizio Scaltriti

    Хэвлэсэн 2020
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  18. 18
    High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer

    High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer -н Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Abel González-Pérez, Mafalda Oliveira, Fara Brasó‐Maristany, Nusaïbah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, María Teresa Herrera-Abreu, Andreu Òdena, Mònica Sánchez-Guixé, Marta Capelán, Analía Azaro, Alejandra Bruna, Olga Rodríguez, Marta Guzmán, Judit Grueso, Cristina Viaplana, Javier Hernández‐Losa, Faye Su, Kui Lin, Robert B. Clarke, Carlos Caldas, Joaquı́n Arribas, Stefan Michiels, Alicia García‐Sanz, Nicholas C. Turner, Aleix Prat, Paolo Nucíforo, R. Dienstmann, Chandra Verma, Núria López-Bigas, Maurizio Scaltriti, Mónica Arnedos, Cristina Saura, Violeta Serra

    Хэвлэсэн 2021
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  19. 19
    High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer

    High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer -н Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Abel González-Pérez, Mafalda Oliveira, Fara Brasó‐Maristany, Nusaïbah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, María Teresa Herrera-Abreu, Andreu Òdena, Mònica Sánchez-Guixé, Marta Capelán, Analía Azaro, Alejandra Bruna, Olga Rodríguez, Marta Guzmán, Judit Grueso, Cristina Viaplana, Javier Hernández‐Losa, Faye Su, Kui Lin, Robert B. Clarke, Carlos Caldas, Joaquı́n Arribas, Stefan Michiels, Alicia García‐Sanz, Nicholas C. Turner, Aleix Prat, Paolo Nucíforo, Rodrigo Dienstmann, Chandra Verma, Núria López-Bigas, Maurizio Scaltriti, Mónica Arnedos, Cristina Saura, Violeta Serra

    Хэвлэсэн 2022
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    Artigo
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