Resultados de búsqueda - Soumya S. Ray

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  1. 1
    Crystal Structure of the Flagellar σ/Anti-σ Complex σ28/FlgM Reveals an Intact σ Factor in an Inactive Conformation

    Crystal Structure of the Flagellar σ/Anti-σ Complex σ28/FlgM Reveals an Intact σ Factor in an Inactive Conformation por Margareta K. Sörenson, Soumya S. Ray, Seth A. Darst

    Publicado 2004
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  2. 2
    Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation

    Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation por Soumya S. Ray, Richard J. Nowak, Robert H. Brown, Peter T. Lansbury

    Publicado 2005
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  3. 3
    The Parkinson Disease-linked LRRK2 Protein Mutation I2020T Stabilizes an Active State Conformation Leading to Increased Kinase Activity

    The Parkinson Disease-linked LRRK2 Protein Mutation I2020T Stabilizes an Active State Conformation Leading to Increased Kinase Activity por Soumya S. Ray, Samantha Bender, Stephanie Kang, Regina Lin, Marcie A. Glicksman, Min Liu

    Publicado 2014
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  4. 4
    Triosephosphate isomerase from Plasmodium falciparum:. the crystal structure provides insights into antimalarial drug design

    Triosephosphate isomerase from Plasmodium falciparum:. the crystal structure provides insights into antimalarial drug design por Sameer Velanker, Soumya S. Ray, Rajesh S. Gokhale, S Suma, Hemalatha Balaram, P. Balaram, MRN Murthy

    Publicado 1997
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  5. 5
    Type II Kinase Inhibitors Show an Unexpected Inhibition Mode against Parkinson’s Disease-Linked LRRK2 Mutant G2019S

    Type II Kinase Inhibitors Show an Unexpected Inhibition Mode against Parkinson’s Disease-Linked LRRK2 Mutant G2019S por Min Liu, Samantha Bender, Gregory D. Cuny, Woody Sherman, Marcie A. Glicksman, Soumya S. Ray

    Publicado 2013
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  6. 6
    Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer’s Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data

    Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer’s Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data por Petr Kočiš, Martin Tolar, Yongxin Yu, William Sinko, Soumya S. Ray, Kaj Blennow, Howard Fillit, John A. Hey

    Publicado 2017
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  7. 7
    Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations

    Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations por Kevin Hauser, Christopher Negron, Steven K. Albanese, Soumya S. Ray, Thomas Steinbrecher, Robert Abel, John D. Chodera, Lingle Wang

    Publicado 2018
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  8. 8
    Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH

    Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH por Sivapriya Kirubakaran, Suresh Kumar Gorla, Lisa Sharling, Minjia Zhang, Xiaoping Liu, Soumya S. Ray, Iain Macpherson, Boris Striepen, Lizbeth Hedstrom, Gregory D. Cuny

    Publicado 2012
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  9. 9
    Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1

    Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1 por Chittaranjan Das, Quyen Q. Hoang, C.A. Kreinbring, Sarah J. Luchansky, Robin K. Meray, Soumya S. Ray, Peter T. Lansbury, Dagmar Ringe, Gregory A. Petsko

    Publicado 2006
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  10. 10
    The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1.

    The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. por David W. Rodgers, S.J. Gamblin, Bruce A. Harris, Soumya S. Ray, J S Culp, Brian D. Hellmig, Deborah J. Woolf, Christine Debouck, Stephen C. Harrison

    Publicado 1995
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  11. 11
    Structure–activity relationship study of beta-carboline derivatives as haspin kinase inhibitors

    Structure–activity relationship study of beta-carboline derivatives as haspin kinase inhibitors por Gregory D. Cuny, Natalia P. Ulyanova, Debasis Patnaik, Jifeng Liu, Xiangjie Lin, Ken Auerbach, Soumya S. Ray, Jun Xian, Marcie A. Glicksman, Ross L. Stein, Jonathan M.G. Higgins

    Publicado 2012
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  12. 12
    Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1

    Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1 por Malek Najjar, Chalada Suebsuwong, Soumya S. Ray, Roshan J. Thapa, Jenny L. Maki, Shoko Nogusa, Saumil Shah, Danish Saleh, Peter J. Gough, John Bertin, Junying Yuan, Siddharth Balachandran, Gregory D. Cuny, Alexei Degterev

    Publicado 2015
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  13. 13
    Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors

    Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors por Peter Canning, Qui Ruan, Tobias Schwerd, Matouš Hrdinka, Jenny L. Maki, Danish Saleh, Chalada Suebsuwong, Soumya S. Ray, Paul E. Brennan, Gregory D. Cuny, Holm H. Uhlig, Mads Gyrd‐Hansen, Alexei Degterev, Alex N. Bullock

    Publicado 2015
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  14. 14
    Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates

    Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates por Jeremy R. Duvall, Joshua D. Thomas, Raghida A. Bukhalid, Kalli C. Catcott, K. W. Bentley, Scott D. Collins, Timothy K. Eitas, Brian Jones, Eugene Kelleher, Kelly L. Lancaster, Marina Protopopova, Soumya S. Ray, Elena Ter‐Ovanesyan, Ling Xu, Liping Yang, Jeffrey Zurita, Marc Damelin, Dorin Toader, Timothy B. Lowinger

    Publicado 2023
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  15. 15
    Structural genomics: A pipeline for providing structures for the biologist

    Structural genomics: A pipeline for providing structures for the biologist por Mark R. Chance, Anne R. Bresnick, S.K. Burley, Jiansheng Jiang, Christopher D. Lima, Andrej Šali, Steven C. Almo, J.B. Bonanno, John A. Buglino, Simon J. Boulton, Hua Chen, Narayanan Eswar, Guo-Shun He, Raymond Y. Huang, Valentin Ilyin, Linda McMahan, Ursula Pieper, Soumya S. Ray, Marc Vidal, Li‐Kai Wang

    Publicado 2002
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