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The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway Tekijä Yuzuru Imai, Yoshito Kobayashi, Tsuyoshi Inoshita, Hongrui Meng, Taku Arano, Kengo Uemura, Takeshi Asano, Kenji Yoshimi, Chang-Liang Zhang, Gen Matsumoto, Toshiyuki Ohtsuka, Ryoichiro Kageyama, Hiroshi Kiyonari, Go Shioi, Nobuyuki Nukina, Nobutaka Hattori, Ryōsuke Takahashi

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease Tekijä Ranjita Betarbet, Todd Sherer, Gillian M. MacKenzie, Monica Garcia‐Osuna, Alexander Panov, J. Timothy Greenamyre

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Measurement of LRRK2 and Ser910/935 Phosphorylated LRRK2 in Peripheral Blood Mononuclear Cells from Idiopathic Parkinson's Disease Patients Tekijä Nicolas Dzamko, Germaine Chua, Madelaine Ranola, Dominic B. Rowe, Glenda M. Halliday

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α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins Tekijä Natalie Ostrerova, Leonard Petrucelli, Matthew J. Farrer, Nitinkumar Mehta, Peter S. Choi, John Hardy, Benjamin Wolozin

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Genetic analysis of LRRK2 functional domains in Brazilian patients with Parkinson’s disease Tekijä Cláudia Bueno Abdalla-Carvalho, Cíntia Barros Santos-Rebouças, Bonfim Guimarães, Mário Campos, João Santos Pereira, Ana Lúcia Zuma de Rosso, Denise Hack Nicaretta, M. Marinho e Silva, Jussara Mendonça dos Santos, Márcia Mattos Gonçalves Pimentel

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Replication of GWAS Associations for GAK and MAPT in Parkinson's Disease Tekijä Shannon Rhodes, Janet S. Sinsheimer, Yvette Bordelon, Jeff M. Bronstein, Beate Ritz

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Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration Tekijä João Paulo Lima Daher, Hisham Abdelmotilib, Xianzhen Hu, Laura A. Volpicelli‐Daley, Mark S. Moehle, Kyle Fraser, Elie Needle, Yi Chen, Stefanus J. Steyn, Paul Galatsis, Warren D. Hirst, Andrew B. West

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LRRK2 in Parkinson’s disease: biochemical functions Tekijä Vasanti S. Anand, Steven P. Braithwaite

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Parkinson disease phenotype in Ashkenazi jews with and without <i>LRRK2</i> G2019S mutations Tekijä Roy N. Alcalay, Anat Mirelman, Rachel Saunders‐Pullman, Ming‐X Tang, Helen Mejia Santana, Deborah Raymond, Ernest Roos, Martha Orbe‐Reilly, Tanya Gurevich, Anat Bar Shira, Mali Gana Weisz, Kira Yasinovsky, Maayan Zalis, Avner Thaler, Andres Deik, Matthew J. Barrett, Jose Cabassa, Mark Groves, Ann Hunt, Naomi Lubarr, Marta San Luciano, Joan Miravite, Christina A. Palmese, Rivka Sachdev, Harini Sarva, Lawrence Severt, Vicki Shanker, Matthew Swan, Jeannie Soto‐Valencia, Brooke Johannes, Robert Ortega, Stanley Fahn, Lucien Côté, Cheryl Waters, Pietro Mazzoni, Blair Ford, Elan D. Louis, Oren Levy, Llency Rosado, Dylanis Lopez Ruiz, Tsvyatko Dorovski, Michael W. Pauciulo, William C. Nichols, Avi Orr‐Urtreger, Laurie J. Ozelius, Lorraine N. Clark, Nir Giladi, Susan Bressman, Karen Marder

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Lysosomal impairment in Parkinson's disease Tekijä Benjamin Dehay, Marta Martínez‐Vicente, Guy A. Caldwell, Kim A. Caldwell, Zhenyue Yue, Mark Cookson, Christine Klein, Miquel Vila, Erwan Bézard

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Emerging pathways in genetic Parkinson’s disease: Autosomal‐recessive genes in Parkinson’s disease – a common pathway? Tekijä Julia C. Fitzgerald, Hélène Plun‐Favreau

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Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant Tekijä Veronique Daniëls, Renée Vancraenenbroeck, Bernard M. H. Law, Elisa Greggio, Evy Lobbestael, Fangye Gao, Marc De Maeyer, Mark Cookson, Kirsten Harvey, Veerle Baekelandt, Jean‐Marc Taymans

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Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI) Tekijä Mike A. Nalls, Margaux F. Keller, Dena Hernández, Lan Chen, David J. Stone, Andrew Singleton

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Parkinson’s disease: A genetic perspective Tekijä Andrea Carmine Belin, Marie Westerlund

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The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus Tekijä Eric S. Sweet, Bernardette T. Saunier-Rébori, Zhenyu Yue, Robert D. Blitzer

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<i>LRRK2</i> mutations and risk variants in Japanese patients with Parkinson's disease Tekijä Cyrus P. Zabetian, Mitsutoshi Yamamoto, Alexis N. Lopez, Hiroshi Ujike, Ignácio F. Mata, Yuishin Izumi, Ryuji Kaji, Hirofumi Maruyama, Hiroyuki Morino, Masaya Oda, Carolyn M. Hutter, Karen L. Edwards, Gerard D. Schellenberg, Debby W. Tsuang, Dora Yearout, Eric B. Larson, Hideshi Kawakami

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LRRK2: Cause, Risk, and Mechanism Tekijä Coro Paisán‐Ruíz, Patrick A. Lewis, Andrew Singleton

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Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression Tekijä Dong Hwan Ho, Hye Jung Kim, Jisun Kim, Hyuna Sim, Hyunjun Ahn, Janghwan Kim, Hyemyung Seo, Kwang Chul Chung, Bum-Joon Park, Ilhong Son, Wongi Seol

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Pathways to Parkinsonism Redux: convergent pathobiological mechanisms in genetics of Parkinson's disease Tekijä Ravindran Kumaran, Mark Cookson

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Variants in GBA , SNCA , and MAPT influence Parkinson disease risk, age at onset, and progression Tekijä Albert A. Davis, Kristin M. Andruska, Bruno A. Benítez, Brad A. Racette, Joel S. Perlmutter, Carlos Cruchaga

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