Hakutulokset - Siraj M. Ali

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  1. 1
    Structure of S6 Kinase 1 Determines whether Raptor-mTOR or Rictor-mTOR Phosphorylates Its Hydrophobic Motif Site

    Structure of S6 Kinase 1 Determines whether Raptor-mTOR or Rictor-mTOR Phosphorylates Its Hydrophobic Motif Site Tekijä Siraj M. Ali, David M. Sabatini

    Julkaistu 2005
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  2. 2
    A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1

    A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1 Tekijä Allison Allen, Siraj M. Ali, Kyle Gowen, Julia A. Elvin, Tanja Pejović

    Julkaistu 2017
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  3. 3
    Intracranial Activity of Cabozantinib in MET Exon 14–Positive NSCLC with Brain Metastases

    Intracranial Activity of Cabozantinib in MET Exon 14–Positive NSCLC with Brain Metastases Tekijä Samuel J. Klempner, Ali Borghei, Behrooz Hakimian, Siraj M. Ali, Sai‐Hong Ignatius Ou

    Julkaistu 2016
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  4. 4
    MET 14 Deletion in Sarcomatoid Non-Small-Cell Lung Cancer Detected by Next-Generation Sequencing and Successfully Treated with a MET Inhibitor

    MET 14 Deletion in Sarcomatoid Non-Small-Cell Lung Cancer Detected by Next-Generation Sequencing and Successfully Treated with a MET Inhibitor Tekijä Carrie B. Lee, Dimitry Usenko, Garrett M. Frampton, Caitlin McMahon, Siraj M. Ali, Jared Weiss

    Julkaistu 2015
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  5. 5
    Clinical response to everolimus in a patient with Hodgkin’s lymphoma harboring a TSC2 mutation

    Clinical response to everolimus in a patient with Hodgkin’s lymphoma harboring a TSC2 mutation Tekijä Guilherme Fleury Perini, Paulo Vidal Campregher, Jeffrey S. Ross, Siraj M. Ali, Nelson Hamerschlak, Fabio P S Santos

    Julkaistu 2016
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  6. 6
    Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with <i>FGF/FGFR</i> Aberrations Across Urinary Tract Tumors

    Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with <i>FGF/FGFR</i> Aberrations Across Urinary Tract Tumors Tekijä Denis L. Jardim, Sherri Z. Millis, Jeffrey S. Ross, Scott M. Lippman, Siraj M. Ali, Razelle Kurzrock

    Julkaistu 2022
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  7. 7
    Cyclin Pathway Genomic Alterations Across 190,247 Solid Tumors: Leveraging Large-Scale Data to Inform Therapeutic Directions

    Cyclin Pathway Genomic Alterations Across 190,247 Solid Tumors: Leveraging Large-Scale Data to Inform Therapeutic Directions Tekijä Denis L. Jardim, Sherri Z. Millis, Jeffrey S. Ross, Michelle Sue-Ann Woo, Siraj M. Ali, Razelle Kurzrock

    Julkaistu 2020
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  8. 8
    Landscape of Cyclin Pathway Genomic Alterations Across 5,356 Prostate Cancers: Implications for Targeted Therapeutics

    Landscape of Cyclin Pathway Genomic Alterations Across 5,356 Prostate Cancers: Implications for Targeted Therapeutics Tekijä Denis L. Jardim, Sherri Z. Millis, Jeffrey S. Ross, Michelle Sue-Ann Woo, Siraj M. Ali, Razelle Kurzrock

    Julkaistu 2021
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  9. 9
    Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

    Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux Tekijä Andrew M. Cameron, Joseph P. Steiner, A. Jane Roskams, Siraj M. Ali, Gabriele V. Ronnettt, Solomon H. Snyder

    Julkaistu 1995
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  10. 10
    Tumor Mutational Burden Guides Therapy in a Treatment Refractory <i>POLE-</i>Mutant Uterine Carcinosarcoma

    Tumor Mutational Burden Guides Therapy in a Treatment Refractory <i>POLE-</i>Mutant Uterine Carcinosarcoma Tekijä Munveer S. Bhangoo, Peter D. Boasberg, Pareen Mehta, Julia A. Elvin, Siraj M. Ali, Winnie Wu, Samuel J. Klempner

    Julkaistu 2018
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  11. 11
    Detection of Known and Novel FGFR Fusions in Non–Small Cell Lung Cancer by Comprehensive Genomic Profiling

    Detection of Known and Novel FGFR Fusions in Non–Small Cell Lung Cancer by Comprehensive Genomic Profiling Tekijä Angel Qin, Adrienne Johnson, Jeffrey S. Ross, Vincent A. Miller, Siraj M. Ali, Alexa B. Schrock, Shirish M. Gadgeel

    Julkaistu 2018
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  12. 12
    Checkpoint inhibitor is active against large cell neuroendocrine carcinoma with high tumor mutation burden

    Checkpoint inhibitor is active against large cell neuroendocrine carcinoma with high tumor mutation burden Tekijä Victoria E. Wang, Anatoly Urisman, Lee A. Albacker, Siraj M. Ali, Vincent A. Miller, Rahul Aggarwal, David M. Jablons

    Julkaistu 2017
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  13. 13
    Phosphatidylinositol 3‐kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities

    Phosphatidylinositol 3‐kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities Tekijä Sherri Z. Millis, Denis L. Jardim, Lee A. Albacker, Jeffrey S. Ross, Vincent A. Miller, Siraj M. Ali, Razelle Kurzrock

    Julkaistu 2018
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  14. 14
    GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR

    GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR Tekijä Do‐Hyung Kim, Dos D. Sarbassov, Siraj M. Ali, Robert Latek, Kalyani Guntur, Hediye Erdjument‐Bromage, Paul Tempst, David M. Sabatini

    Julkaistu 2003
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  15. 15
    Comprehensive genomic profiling identifies novel NTRK fusions in neuroendocrine tumors

    Comprehensive genomic profiling identifies novel NTRK fusions in neuroendocrine tumors Tekijä Darren Sigal, Munveer S. Bhangoo, Jonathan A. Hermel, Dean C. Pavlick, Garrett M. Frampton, Vincent A. Miller, Jeffrey S. Ross, Siraj M. Ali

    Julkaistu 2018
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  16. 16
    mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

    mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery Tekijä Do‐Hyung Kim, Dos D. Sarbassov, Siraj M. Ali, Jessie E. King, Robert Latek, Hediye Erdjument‐Bromage, Paul Tempst, David M. Sabatini

    Julkaistu 2002
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  17. 17
    Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

    Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton Tekijä Dos D. Sarbassov, Siraj M. Ali, Do‐Hyung Kim, David A. Guertin, Robert Latek, Hediye Erdjument‐Bromage, Paul Tempst, David M. Sabatini

    Julkaistu 2004
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  18. 18
    Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

    Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB Tekijä Dos D. Sarbassov, Siraj M. Ali, Shomit Sengupta, Joon-Ho Sheen, Peggy P. Hsu, Alex F. Bagley, Andrew L. Markhard, David M. Sabatini

    Julkaistu 2006
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  19. 19
    FGFR3–TACC3: A novel gene fusion in cervical cancer

    FGFR3–TACC3: A novel gene fusion in cervical cancer Tekijä Benedito A. Carneiro, Julia A. Elvin, Suneel D. Kamath, Siraj M. Ali, Ajit Paintal, Alvaro Restrepo, Emily Berry, Francis J. Giles, Melissa L. Johnson

    Julkaistu 2015
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  20. 20
    Identification of a Novel HIP1-ALK Fusion Variant in Non–Small-Cell Lung Cancer (NSCLC) and Discovery of ALK I1171 (I1171N/S) Mutations in Two ALK-Rearranged NSCLC Patients with Resistance to Alectinib

    Identification of a Novel HIP1-ALK Fusion Variant in Non–Small-Cell Lung Cancer (NSCLC) and Discovery of ALK I1171 (I1171N/S) Mutations in Two ALK-Rearranged NSCLC Patients with Re... Tekijä Sai‐Hong Ignatius Ou, Samuel J. Klempner, Joel Greenbowe, Michele C. Azada, Alexa B. Schrock, Siraj M. Ali, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller

    Julkaistu 2014
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