检索结果 - Shihan He

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  1. 1
    Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia

    Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia 由 Aibin Shi, Marcelo J. Murai, Shihan He, George Lund, Thomas Hartley, Trupta Purohit, Gireesh Reddy, M. Chruszcz, Jolanta Grembecka, Tomasz Cierpicki

    出版 2012
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  2. 2
    High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

    High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction 由 Shihan He, Timothy J. Senter, Jonathan Pollock, Changho Han, Sunil Upadhyay, Trupta Purohit, Rocco D. Gogliotti, Craig W. Lindsley, Tomasz Cierpicki, Shaun R. Stauffer, Jolanta Grembecka

    出版 2014
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  3. 3
    BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization

    BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization 由 Felicia Gray, Hyo Je Cho, Shirish Shukla, Shihan He, Ashley Harris, Bohdan Boytsov, Łukasz Jaremko, Mariusz Jaremko, Borries Demeler, Elizabeth R. Lawlor, Jolanta Grembecka, Tomasz Cierpicki

    出版 2016
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  4. 4
    Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

    Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia 由 Jolanta Grembecka, Shihan He, Aibin Shi, Trupta Purohit, Andrew G. Muntean, Roderick J. Sorenson, Hollis D. Showalter, Marcelo J. Murai, Amalia Marie Belcher, Thomas Hartley, Jay L. Hess, Tomasz Cierpicki

    出版 2012
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  5. 5
    Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner

    Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner 由 Shihan He, B. S. Malik, Dmitry Borkin, Hongzhi Miao, Sudhanshu Shukla, Katarzyna Kempińska, Tanaya A. Purohit, Jingya Wang, L Chen, Brian Parkin, Sami N. Malek, Gwenn Danet-Desnoyers, Andrew G. Muntean, Tomasz Cierpicki, Jolanta Grembecka

    出版 2015
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  6. 6
    Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo

    Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo 由 Dmitry Borkin, Shihan He, Hongzhi Miao, Katarzyna Kempińska, Jonathan Pollock, Jennifer Chase, Trupta Purohit, Bhavna Malik, Ting Zhao, Jingya Wang, Bo Wen, Hongliang Zong, Morgan Jones, Gwenn Danet-Desnoyers, Mónica L. Guzmán, Moshe Talpaz, Dale L. Bixby, Duxin Sun, Jay L. Hess, Andrew G. Muntean, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka

    出版 2015
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  7. 7
    Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

    Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain 由 Shirish Shukla, Weijiang Ying, Felicia Gray, Yiwu Yao, Miranda L. Simes, Qingjie Zhao, Hongzhi Miao, Hyo Je Cho, Paula Gónzález-Alonso, Alyssa Winkler, George Lund, Trupta Purohit, Eungi Kim, Xiaotian Zhang, Joshua M. Ray, Shihan He, Caroline Nikolaidis, Juliano Ndoj, Jingya Wang, Łukasz Jaremko, Mariusz Jaremko, Russell J.H. Ryan, Mónica L. Guzmán, Jolanta Grembecka, Tomasz Cierpicki

    出版 2021
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