Хайлтын үр дүнгүүд - Sherif F. El‐Khamisy

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  1. 1
    A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

    A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage -н Sherif F. El‐Khamisy

    Хэвлэсэн 2003
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    Artigo
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  2. 2
    TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy

    TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy -н Meryem Alagöz, Owen S. Wells, Sherif F. El‐Khamisy

    Хэвлэсэн 2013
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    Artigo
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  3. 3
    Topoisomerase I inhibition in colorectal cancer: biomarkers and therapeutic targets

    Topoisomerase I inhibition in colorectal cancer: biomarkers and therapeutic targets -н Duncan C. Gilbert, Anthony J. Chalmers, Sherif F. El‐Khamisy

    Хэвлэсэн 2011
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  4. 4
    ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells

    ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells -н Meryem Alagöz, Shih‐Chieh Chiang, Abhishek Bharadwaj Sharma, Sherif F. El‐Khamisy

    Хэвлэсэн 2013
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    Artigo
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  5. 5
    APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks

    APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks -н Natasha Iles, Stuart L. Rulten, Sherif F. El‐Khamisy, Keith W. Caldecott

    Хэвлэсэн 2007
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  6. 6
    TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage

    TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage -н Zhihong Zeng, Felipe Cortés‐Ledesma, Sherif F. El‐Khamisy, Keith W. Caldecott

    Хэвлэсэн 2010
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  7. 7
    Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites

    Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites -н Н. А. Лебедева, Н. И. Речкунова, Sherif F. El‐Khamisy, Olga I. Lavrik

    Хэвлэсэн 2012
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  8. 8
    SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair

    SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair -н Jessica J. R. Hudson, Shih‐Chieh Chiang, Owen S. Wells, Chris Rookyard, Sherif F. El‐Khamisy

    Хэвлэсэн 2012
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  9. 9
    DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

    DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity -н Jannigje Rachel Kok, Nelma M. Palminha, Cleide Dos Santos Souza, Sherif F. El‐Khamisy, Laura Ferraiuolo

    Хэвлэсэн 2021
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  10. 10
    Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin

    Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin -н Sherif F. El‐Khamisy, Sachin Katyal, Poorvi Patel, Limei Ju, Peter J. McKinnon, Keith W. Caldecott

    Хэвлэсэн 2009
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  11. 11
    Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection

    Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection -н Angela EM Ibler, Mohamed ElGhazaly, Kathryn Naylor, Natalia A. Bulgakova, Sherif F. El‐Khamisy, Daniel Humphreys

    Хэвлэсэн 2019
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    Artigo
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  12. 12
    DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms

    DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms -н Arwa A. Abugable, Julia L.M. Morris, Nelma M. Palminha, Ringaile Zaksauskaite, Swagat Ray, Sherif F. El‐Khamisy

    Хэвлэсэн 2019
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  13. 13
    Clinical and Cellular Roles for TDP1 and TOP1 in Modulating Colorectal Cancer Response to Irinotecan

    Clinical and Cellular Roles for TDP1 and TOP1 in Modulating Colorectal Cancer Response to Irinotecan -н Cornelia Meisenberg, Duncan C. Gilbert, Anthony J. Chalmers, Vikki Haley, Simon Gollins, Simon E. Ward, Sherif F. El‐Khamisy

    Хэвлэсэн 2014
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  14. 14
    Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage

    Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage -н Shih‐Chieh Chiang, Martin Meagher, Nick Kassouf, Majid Hafezparast, Peter J. McKinnon, Rachel Haywood, Sherif F. El‐Khamisy

    Хэвлэсэн 2017
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  15. 15
    TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo

    TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo -н Sachin Katyal, Sherif F. El‐Khamisy, H. R. Russell, Yang Li, Limei Ju, Keith W. Caldecott, Peter J. McKinnon

    Хэвлэсэн 2007
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  16. 16
    The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1

    The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1 -н Youngsoo Lee, Sachin Katyal, Yang Li, Sherif F. El‐Khamisy, H. R. Russell, Keith W. Caldecott, Peter J. McKinnon

    Хэвлэсэн 2009
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  17. 17
    The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks

    The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks -н Joanna I. Loizou, Sherif F. El‐Khamisy, Anastasia Zlatanou, David Moore, Douglas W. Chan, Jun Qin, Stefania Sarno, Flavio Meggio, Lorenzo A. Pinna, Keith W. Caldecott

    Хэвлэсэн 2004
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  18. 18
    TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1

    TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 -н Zhihong Zeng, Abhishek Bharadwaj Sharma, Limei Ju, Junko Murai, Lieve Umans, Liesbeth Vermeire, Yves Pommier, Shunichi Takeda, Danny Huylebroeck, Keith W. Caldecott, Sherif F. El‐Khamisy

    Хэвлэсэн 2012
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  19. 19
    Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks

    Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks -н Claudia Kerzendorfer, Annabel Whibley, Gillian Carpenter, Emily Outwin, Shih‐Chieh Chiang, Gillian Turner, Charles E. Schwartz, Sherif F. El‐Khamisy, F. Lucy Raymond, Mark O’Driscoll

    Хэвлэсэн 2010
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    Artigo
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  20. 20
    Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan

    Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan -н Cornelia Meisenberg, Mohamed E. Ashour, Lamia El-Shafie, Chunyan Liao, Adam Hodgson, Alice Elizabeth Pilborough, Syed Ali Khurram, Jessica A. Downs, Simon E. Ward, Sherif F. El‐Khamisy

    Хэвлэсэн 2016
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    Artigo
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