Resultats de la cerca

Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors per Éric Solary, Richard Bertrand, KW Kohn, Yves Pommier

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Repair of Topoisomerase I‐Mediated DNA Damage per Yves Pommier, Juana Barceló, V. Ashutosh Rao, Olivier Sordet, Andrew G. Jobson, Laurent Thibaut, Ze‐Hong Miao, Jennifer A. Seiler, Hongliang Zhang, Christophe Marchand, Keli Agama, John L. Nitiss, Christophe E. Redon

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beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin. per C J Li, Lidia Averboukh, Arthur B. Pardee

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Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. per Y H Hsiang, Robert Hertzberg, Sidney M. Hecht, Leroy F. Liu

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Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1 per Barbara Jonchère, Alexandra Vétillard, Bertrand Toutain, David Lam, Anne Charlotte Bernard, Cécile Henry, Sophie de Carné Trécesson, Érick Gamelin, Philippe Juin, Catherine Guette, Olivier Coqueret

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Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. per Christine Jaxel, Giovanni Capranico, Donna Kerrigan, Kurt W. Kohn, Yves Pommier

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Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants. per Anne M. Knab, Jolanta Fertala, Mary‐Ann Bjornsti

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Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site. per Robert Hertzberg, Robert Busby, Mary Jo Caranfa, Kenneth G. Holden, Randall K. Johnson, Sidney M. Hecht, William D. Kingsbury

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MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin per Nunu Huang, Jiangbin Wu, Wei Qiu, Qing Lyu, Jie He, Weidong Xie, Naihan Xu, Yaou Zhang

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Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin. per Eric H. Rubin, Panayotis Pantazis, Ajit Bharti, Deborah Toppmeyer, Beppino C. Giovanella, Donald Küfe

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Perspectives on Biologically Active Camptothecin Derivatives per Ying-Qian Liu, Wen-Qun Li, Susan L. Morris‐Natschke, Keduo Qian, Yang Liu, Gao-Xiang Zhu, Xiao-Bing Wu, An-Liang Chen, Shao-Yong Zhang, Xiang Nan, Kuo‐Hsiung Lee

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True per H.C. Kwaan, J Wang, K Svoboda, Paul Declerck

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Characterization of a camptothecin-resistant human DNA topoisomerase I. per Eigil Kjeldsen, Bjarne J. Bonven, T Andoh, Kazuyuki Ishii, Kosuke Okada, Lars Bolund, Ole Westergaard

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Sequence specificity of DNA topoisomerase I in the presence and absence of camptothecin. per Bo Thomsen, Sarah Mollerup, Bjarne J. Bonven, Rainer Frank, Helmut Blöcker, Ole F. Nielsen, Ole Westergaard

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Targeted Disruption of the Mouse Topoisomerase I Gene by Camptothecin Selection per Scott G. Morham, Kimberly D. Kluckman, Nectarios Voulomanos, Oliver Smithies

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Co-delivery of camptothecin and curcumin by cationic polymeric nanoparticles for synergistic colon cancer combination chemotherapy per Bo Xiao, Xiaoying Si, Xiaodong Zhang, Émilie Viennois, Mingzhen Zhang, Didier Merlin

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CARS based label‐free assay for assessment of drugs by monitoring lipid droplets in tumour cells per Christian Steuwe, Imran I. Patel, Mahmud Ul‐Hasan, A. Schreiner, Joan Boren, Kevin M. Brindle, Stefanie Reichelt, Sumeet Mahajan

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Topoisomerase-specific drug sensitivity in relation to cell cycle progression. per Kuan‐Chih Chow, Warren E. Ross

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Fasting protects against the side effects of irinotecan but preserves its anti-tumor effect in Apc15lox mutant mice per Sander A. Huisman, Wendy Bijman-Lagcher, Jan N.M. IJzermans, Ron Smits, Ron WF de Bruin

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Characterization of DNA damage induced by 3,4-estrone-o-quinone in human cells. per Louise M. Nutter, E O Ngo, Yusuf J. Abul‐Hajj

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