Sökresultat med upphovsmän

1

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage av Sherif F. El‐Khamisy

Publicerad 2003

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TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy av Meryem Alagöz, Owen S. Wells, Sherif F. El‐Khamisy

Publicerad 2013

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Topoisomerase I inhibition in colorectal cancer: biomarkers and therapeutic targets av Duncan C. Gilbert, Anthony J. Chalmers, Sherif F. El‐Khamisy

Publicerad 2011

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ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells av Meryem Alagöz, Shih‐Chieh Chiang, Abhishek Bharadwaj Sharma, Sherif F. El‐Khamisy

Publicerad 2013

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APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks av Natasha Iles, Stuart L. Rulten, Sherif F. El‐Khamisy, Keith W. Caldecott

Publicerad 2007

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TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage av Zhihong Zeng, Felipe Cortés‐Ledesma, Sherif F. El‐Khamisy, Keith W. Caldecott

Publicerad 2010

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Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites av Н. А. Лебедева, Н. И. Речкунова, Sherif F. El‐Khamisy, Olga I. Lavrik

Publicerad 2012

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SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair av Jessica J. R. Hudson, Shih‐Chieh Chiang, Owen S. Wells, Chris Rookyard, Sherif F. El‐Khamisy

Publicerad 2012

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DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity av Jannigje Rachel Kok, Nelma M. Palminha, Cleide Dos Santos Souza, Sherif F. El‐Khamisy, Laura Ferraiuolo

Publicerad 2021

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10

Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin av Sherif F. El‐Khamisy, Sachin Katyal, Poorvi Patel, Limei Ju, Peter J. McKinnon, Keith W. Caldecott

Publicerad 2009

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11

Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection av Angela EM Ibler, Mohamed ElGhazaly, Kathryn Naylor, Natalia A. Bulgakova, Sherif F. El‐Khamisy, Daniel Humphreys

Publicerad 2019

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12

DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms av Arwa A. Abugable, Julia L.M. Morris, Nelma M. Palminha, Ringaile Zaksauskaite, Swagat Ray, Sherif F. El‐Khamisy

Publicerad 2019

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13

Clinical and Cellular Roles for TDP1 and TOP1 in Modulating Colorectal Cancer Response to Irinotecan av Cornelia Meisenberg, Duncan C. Gilbert, Anthony J. Chalmers, Vikki Haley, Simon Gollins, Simon E. Ward, Sherif F. El‐Khamisy

Publicerad 2014

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14

Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage av Shih‐Chieh Chiang, Martin Meagher, Nick Kassouf, Majid Hafezparast, Peter J. McKinnon, Rachel Haywood, Sherif F. El‐Khamisy

Publicerad 2017

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15

TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo av Sachin Katyal, Sherif F. El‐Khamisy, H. R. Russell, Yang Li, Limei Ju, Keith W. Caldecott, Peter J. McKinnon

Publicerad 2007

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16

The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1 av Youngsoo Lee, Sachin Katyal, Yang Li, Sherif F. El‐Khamisy, H. R. Russell, Keith W. Caldecott, Peter J. McKinnon

Publicerad 2009

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17

The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks av Joanna I. Loizou, Sherif F. El‐Khamisy, Anastasia Zlatanou, David Moore, Douglas W. Chan, Jun Qin, Stefania Sarno, Flavio Meggio, Lorenzo A. Pinna, Keith W. Caldecott

Publicerad 2004

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18

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 av Zhihong Zeng, Abhishek Bharadwaj Sharma, Limei Ju, Junko Murai, Lieve Umans, Liesbeth Vermeire, Yves Pommier, Shunichi Takeda, Danny Huylebroeck, Keith W. Caldecott, Sherif F. El‐Khamisy

Publicerad 2012

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19

Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks av Claudia Kerzendorfer, Annabel Whibley, Gillian Carpenter, Emily Outwin, Shih‐Chieh Chiang, Gillian Turner, Charles E. Schwartz, Sherif F. El‐Khamisy, F. Lucy Raymond, Mark O’Driscoll

Publicerad 2010

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20

Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan av Cornelia Meisenberg, Mohamed E. Ashour, Lamia El-Shafie, Chunyan Liao, Adam Hodgson, Alice Elizabeth Pilborough, Syed Ali Khurram, Jessica A. Downs, Simon E. Ward, Sherif F. El‐Khamisy

Publicerad 2016

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Sökresultat - Sherif F. El‐Khamisy

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage av Sherif F. El‐Khamisy

TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy av Meryem Alagöz, Owen S. Wells, Sherif F. El‐Khamisy

Topoisomerase I inhibition in colorectal cancer: biomarkers and therapeutic targets av Duncan C. Gilbert, Anthony J. Chalmers, Sherif F. El‐Khamisy

ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells av Meryem Alagöz, Shih‐Chieh Chiang, Abhishek Bharadwaj Sharma, Sherif F. El‐Khamisy

APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks av Natasha Iles, Stuart L. Rulten, Sherif F. El‐Khamisy, Keith W. Caldecott

TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage av Zhihong Zeng, Felipe Cortés‐Ledesma, Sherif F. El‐Khamisy, Keith W. Caldecott

Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites av Н. А. Лебедева, Н. И. Речкунова, Sherif F. El‐Khamisy, Olga I. Lavrik

SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair av Jessica J. R. Hudson, Shih‐Chieh Chiang, Owen S. Wells, Chris Rookyard, Sherif F. El‐Khamisy

DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity av Jannigje Rachel Kok, Nelma M. Palminha, Cleide Dos Santos Souza, Sherif F. El‐Khamisy, Laura Ferraiuolo

Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin av Sherif F. El‐Khamisy, Sachin Katyal, Poorvi Patel, Limei Ju, Peter J. McKinnon, Keith W. Caldecott

Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection av Angela EM Ibler, Mohamed ElGhazaly, Kathryn Naylor, Natalia A. Bulgakova, Sherif F. El‐Khamisy, Daniel Humphreys

DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms av Arwa A. Abugable, Julia L.M. Morris, Nelma M. Palminha, Ringaile Zaksauskaite, Swagat Ray, Sherif F. El‐Khamisy

Clinical and Cellular Roles for TDP1 and TOP1 in Modulating Colorectal Cancer Response to Irinotecan av Cornelia Meisenberg, Duncan C. Gilbert, Anthony J. Chalmers, Vikki Haley, Simon Gollins, Simon E. Ward, Sherif F. El‐Khamisy

Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage av Shih‐Chieh Chiang, Martin Meagher, Nick Kassouf, Majid Hafezparast, Peter J. McKinnon, Rachel Haywood, Sherif F. El‐Khamisy

TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo av Sachin Katyal, Sherif F. El‐Khamisy, H. R. Russell, Yang Li, Limei Ju, Keith W. Caldecott, Peter J. McKinnon

The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1 av Youngsoo Lee, Sachin Katyal, Yang Li, Sherif F. El‐Khamisy, H. R. Russell, Keith W. Caldecott, Peter J. McKinnon

The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks av Joanna I. Loizou, Sherif F. El‐Khamisy, Anastasia Zlatanou, David Moore, Douglas W. Chan, Jun Qin, Stefania Sarno, Flavio Meggio, Lorenzo A. Pinna, Keith W. Caldecott

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 av Zhihong Zeng, Abhishek Bharadwaj Sharma, Limei Ju, Junko Murai, Lieve Umans, Liesbeth Vermeire, ﻿Yves Pommier, Shunichi Takeda, Danny Huylebroeck, Keith W. Caldecott, Sherif F. El‐Khamisy

Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan av Cornelia Meisenberg, Mohamed E. Ashour, Lamia El-Shafie, Chunyan Liao, Adam Hodgson, Alice Elizabeth Pilborough, Syed Ali Khurram, Jessica A. Downs, Simon E. Ward, Sherif F. El‐Khamisy

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TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 av Zhihong Zeng, Abhishek Bharadwaj Sharma, Limei Ju, Junko Murai, Lieve Umans, Liesbeth Vermeire, Yves Pommier, Shunichi Takeda, Danny Huylebroeck, Keith W. Caldecott, Sherif F. El‐Khamisy