Zoekresultaten - Shaomeng Wang

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  1. 1
    Targeting the MDM2-p53 Interaction for Cancer Therapy

    Targeting the MDM2-p53 Interaction for Cancer Therapy door Sanjeev Shangary, Shaomeng Wang

    Gepubliceerd in 2008
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  2. 2
    Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

    Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy door Sanjeev Shangary, Shaomeng Wang

    Gepubliceerd in 2008
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  3. 3
    Hydrophobic Binding Hot Spots of Bcl-xL Protein−Protein Interfaces by Cosolvent Molecular Dynamics Simulation

    Hydrophobic Binding Hot Spots of Bcl-xL Protein−Protein Interfaces by Cosolvent Molecular Dynamics Simulation door Chao‐Yie Yang, Shaomeng Wang

    Gepubliceerd in 2011
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  4. 4
    Small Molecule Inhibitors of MDM2-p53 and MDMX-p53 Interactions as New Cancer Therapeutics

    Small Molecule Inhibitors of MDM2-p53 and MDMX-p53 Interactions as New Cancer Therapeutics door Yujun Zhao, Denzil Bernard, Shaomeng Wang

    Gepubliceerd in 2013
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  5. 5
    Small-molecule SMAC mimetics as new cancer therapeutics

    Small-molecule SMAC mimetics as new cancer therapeutics door Longchuan Bai, David C. Smith, Shaomeng Wang

    Gepubliceerd in 2014
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  6. 6
    A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells

    A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells door Hui Song, Renxiao Wang, Shaomeng Wang, Jiayuh Lin

    Gepubliceerd in 2005
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  7. 7
    Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment

    Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment door Yujun Zhao, Angelo Aguilar, Denzil Bernard, Shaomeng Wang

    Gepubliceerd in 2014
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  8. 8
    AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins, inhibits progression of human ovarian cancer

    AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins, inhibits progression of human ovarian cancer door Melissa K. Brunckhorst, Dimitry Lerner, Shaomeng Wang, Qin Yu

    Gepubliceerd in 2012
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  9. 9
    Elucidation of Resistance Mechanisms to Second-Generation ALK Inhibitors Alectinib and Ceritinib in Non–Small Cell Lung Cancer Cells

    Elucidation of Resistance Mechanisms to Second-Generation ALK Inhibitors Alectinib and Ceritinib in Non–Small Cell Lung Cancer Cells door Xuyuan Dong, Ester Fernández‐Salas, Enxiao Li, Shaomeng Wang

    Gepubliceerd in 2016
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  10. 10
    Retinal pigment epithelial cell necroptosis in response to sodium iodate

    Retinal pigment epithelial cell necroptosis in response to sodium iodate door Jakub Hanus, Chastain Anderson, David Sarraf, Jing Ma, Shaomeng Wang

    Gepubliceerd in 2016
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  11. 11
    Resistance to BET Inhibitor Leads to Alternative Therapeutic Vulnerabilities in Castration-Resistant Prostate Cancer

    Resistance to BET Inhibitor Leads to Alternative Therapeutic Vulnerabilities in Castration-Resistant Prostate Cancer door Aishwarya Pawar, Paradesi Naidu Gollavilli, Shaomeng Wang, Irfan A. Asangani

    Gepubliceerd in 2018
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  12. 12
    A system for characterizing cellular and molecular events in programmed neuronal cell death

    A system for characterizing cellular and molecular events in programmed neuronal cell death door RN Pittman, Shaomeng Wang, A. J. DiBenedetto, Jason C. Mills

    Gepubliceerd in 1993
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  13. 13
    Analysis of the Binding of Mixed Lineage Leukemia 1 (MLL1) and Histone 3 Peptides to WD Repeat Domain 5 (WDR5) for the Design of Inhibitors of the MLL1−WDR5 Interaction

    Analysis of the Binding of Mixed Lineage Leukemia 1 (MLL1) and Histone 3 Peptides to WD Repeat Domain 5 (WDR5) for the Design of Inhibitors of the MLL1−WDR5 Interaction door Hacer Karataş, Elizabeth C. Townsend, Denzil Bernard, Yali Dou, Shaomeng Wang

    Gepubliceerd in 2010
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  14. 14
    Targeting the MDM2–p53 Protein–Protein Interaction for New Cancer Therapy: Progress and Challenges

    Targeting the MDM2–p53 Protein–Protein Interaction for New Cancer Therapy: Progress and Challenges door Shaomeng Wang, Yujun Zhao, Angelo Aguilar, Denzil Bernard, Chao‐Yie Yang

    Gepubliceerd in 2017
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  15. 15
    A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo

    A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo door Lijie Zhao, Xin Han, Jianfeng Lü, Donna McEachern, Shaomeng Wang

    Gepubliceerd in 2020
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  16. 16
    Importance of Ligand Reorganization Free Energy in Protein−Ligand Binding-Affinity Prediction

    Importance of Ligand Reorganization Free Energy in Protein−Ligand Binding-Affinity Prediction door Chao‐Yie Yang, Haiying Sun, Jianyong Chen, Zaneta Nikolovska‐Coleska, Shaomeng Wang

    Gepubliceerd in 2009
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  17. 17
    The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response

    The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response door Li Mo, Lin-Yu Lu, Chao‐Yie Yang, Shaomeng Wang, Xiaochun Yu

    Gepubliceerd in 2013
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  18. 18
    RNF111-Dependent Neddylation Activates DNA Damage-Induced Ubiquitination

    RNF111-Dependent Neddylation Activates DNA Damage-Induced Ubiquitination door Teng Ma, Yibin Chen, Feng Zhang, Chao-Yie Yang, Shaomeng Wang, Xiaochun Yu

    Gepubliceerd in 2013
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  19. 19
    Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders

    Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders door Jiuling Yang, Yangbing Li, Angelo Aguilar, Zhaomin Liu, Chao‐Yie Yang, Shaomeng Wang

    Gepubliceerd in 2019
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  20. 20
    Targeting the Estrogen Receptor for the Treatment of Breast Cancer: Recent Advances and Challenges

    Targeting the Estrogen Receptor for the Treatment of Breast Cancer: Recent Advances and Challenges door Rohan Kalyan Rej, J. Thomas, Ranjan Kumar Acharyya, James M. Rae, Shaomeng Wang

    Gepubliceerd in 2023
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