Výsledky vyhledávání - Sevan Habeshian
- Zobrazuji výsledky 1 - 9 z 9
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Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library Autor Alexander Litovchick, Christoph E. Dumelin, Sevan Habeshian, Diana Gikunju, Marie-Aude Guié, Paolo A. Centrella, Ying Zhang, Eric A. Sigel, John W. Cuozzo, Anthony D. Keefe, Matthew Clark
Vydáno 2015Artigo -
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De novo development of small cyclic peptides that are orally bioavailable Autor Manuel L. Merz, Sevan Habeshian, Bo Li, Jean-Alexandre G. L. David, Alexander L. Nielsen, Xinjian Ji, Khaled Il Khwildy, Maury M. Duany Benitez, Phoukham Phothirath, Christian Heinis
Vydáno 2023Artigo -
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Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA‐Encoded Chemical Library Autor John W. Cuozzo, Paolo A. Centrella, Diana Gikunju, Sevan Habeshian, Christopher D. Hupp, Anthony D. Keefe, Eric A. Sigel, Holly H. Soutter, Heather A. Thomson, Ying Zhang, Matthew Clark
Vydáno 2017Artigo -
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Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale Autor Sevan Habeshian, Manuel L. Merz, Gontran Sangouard, Mothukuri Ganesh Kumar, Mischa Schüttel, Zsolt Bognár, Cristina Díaz‐Perlas, J.-M. Vesin, Julien Bortoli Chapalay, Gerardo Turcatti, Laura Cendron, Alessandro Angelini, Christian Heinis
Vydáno 2022Artigo -
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Discovery of cofactor-specific, bactericidal <i>Mycobacterium tuberculosis</i> InhA inhibitors using DNA-encoded library technology Autor Holly H. Soutter, Paolo A. Centrella, Matthew Clark, John W. Cuozzo, Christoph E. Dumelin, Marie-Aude Guié, Sevan Habeshian, Anthony D. Keefe, Kaitlyn M. Kennedy, Eric A. Sigel, Dawn M. Troast, Ying Zhang, Andrew D. Ferguson, Gareth M. Davies, Eleanor Rachel Stead, J. Breed, Prashanti Madhavapeddi, Jon Read
Vydáno 2016Artigo -
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Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target Autor Dean G. Brown, Giles A. Brown, Paolo A. Centrella, Kaan Certel, Roger Cooke, John W. Cuozzo, Niek Dekker, Christoph E. Dumelin, Andrew D. Ferguson, Cédric Fiez-Vandal, Stefan Geschwindner, Marie-Aude Guié, Sevan Habeshian, Anthony D. Keefe, Oliver Schlenker, Eric A. Sigel, Arjan Snijder, Holly H. Soutter, Linda Sundström, Dawn M. Troast, Giselle R. Wiggin, Jing Zhang, Ying Zhang, Matthew Clark
Vydáno 2018Artigo -
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Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors Autor Jeffrey W. Johannes, Stephanie M. Bates, Carl Beigie, Matthew A. Belmonte, John Breen, Shenggen Cao, Paolo A. Centrella, Matthew Clark, John W. Cuozzo, Christoph E. Dumelin, Andrew D. Ferguson, Sevan Habeshian, David Hargreaves, Camil Joubran, Steven L. Kazmirski, Anthony D. Keefe, Michelle L. Lamb, Haiye Lan, Yunxia Li, Hao Ma, Scott N. Mlynarski, Martin J. Packer, Philip B. Rawlins, Daniel Robbins, Haidong Shen, Eric A. Sigel, Holly H. Soutter, Nancy Su, Dawn M. Troast, Haiyun Wang, Kate F. Wickson, Chengyan Wu, Ying Zhang, Qiuying Zhao, Xiaolan Zheng, Alexander W. Hird
Vydáno 2016Artigo
Vyhledávací nástroje:
Související témata
Biology
Chemistry
Biochemistry
Computational biology
Combinatorial chemistry
Computer science
DNA
Drug discovery
Gene
Medicine
Receptor
Cell biology
Enzyme
Peptide
Protease
Small molecule
Adhesion
Allosteric regulation
Antibody
Antigen
Artificial intelligence
Avidity
Bioavailability
Biopharmaceutical
Biophysics
Biotechnology
Bruton's tyrosine kinase
Cell
Cell adhesion
Chemical ligation