檢索結果 - Seng H. Cheng

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  1. 1
    Gaucher-related synucleinopathies: The examination of sporadic neurodegeneration from a rare (disease) angle

    Gaucher-related synucleinopathies: The examination of sporadic neurodegeneration from a rare (disease) angle 由 S. Pablo Sardi, Seng H. Cheng, Lamya S. Shihabuddin

    出版 2015
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  2. 2
    High and Sustained Transgene Expression in Vivo from Plasmid Vectors Containing a Hybrid Ubiquitin Promoter

    High and Sustained Transgene Expression in Vivo from Plasmid Vectors Containing a Hybrid Ubiquitin Promoter 由 Nelson S. Yew, Malgorzata Przybylska, Robin J. Ziegler, Dapei Liu, Seng H. Cheng

    出版 2001
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  3. 3
    Contribution of Toll-like Receptor 9 Signaling to the Acute Inflammatory Response to Nonviral Vectors

    Contribution of Toll-like Receptor 9 Signaling to the Acute Inflammatory Response to Nonviral Vectors 由 Hongmei Zhao, Hiraoki Hemmi, Shizuo Akira, Seng H. Cheng, Ronald K. Scheule, Nelson S. Yew

    出版 2004
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  4. 4
    CRISPR/Cas9-Mediated Genome Editing as a Therapeutic Approach for Leber Congenital Amaurosis 10

    CRISPR/Cas9-Mediated Genome Editing as a Therapeutic Approach for Leber Congenital Amaurosis 10 由 Guo-Xiang Ruan, Elizabeth Barry, Dan Yu, Michael Lukason, Seng H. Cheng, Abraham Scaria

    出版 2017
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  5. 5
    Reversibility of neuropathology in Tay–Sachs-related diseases

    Reversibility of neuropathology in Tay–Sachs-related diseases 由 María-Begoña Cachón-González, Susan Z. Wang, Robin J. Ziegler, Seng H. Cheng, Timothy M. Cox

    出版 2013
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  6. 6
    Reduced Inflammatory Response to Plasmid DNA Vectors by Elimination and Inhibition of Immunostimulatory CpG Motifs

    Reduced Inflammatory Response to Plasmid DNA Vectors by Elimination and Inhibition of Immunostimulatory CpG Motifs 由 Nelson S. Yew, Hongmei Zhao, I‐Huan Wu, Antonius Song, Jennifer D. Tousignant, Malgorzata Przybylska, Seng H. Cheng

    出版 2000
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  7. 7
    CpG-Depleted Plasmid DNA Vectors with Enhanced Safety and Long-Term Gene Expression in Vivo

    CpG-Depleted Plasmid DNA Vectors with Enhanced Safety and Long-Term Gene Expression in Vivo 由 Nelson S. Yew, Hongmei Zhao, Malgorzata Przybylska, I‐Huan Wu, Jennifer D. Tousignant, Ronald K. Scheule, Seng H. Cheng

    出版 2002
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  8. 8
    Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes

    Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes 由 Hongmei Zhao, Malgorzata Przybylska, I-Huan Wu, Jinhua Zhang, Craig Siegel, Svetlana Komarnitsky, Nelson S. Yew, Seng H. Cheng

    出版 2007
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  9. 9
    Conjugation of Mannose 6-Phosphate-containing Oligosaccharides to Acid α-Glucosidase Improves the Clearance of Glycogen in Pompe Mice

    Conjugation of Mannose 6-Phosphate-containing Oligosaccharides to Acid α-Glucosidase Improves the Clearance of Glycogen in Pompe Mice 由 Yunxiang Zhu, Xuemei Li, Josephine Kyazike, Qun Zhou, Beth L. Thurberg, Nina Raben, Robert J. Mattaliano, Seng H. Cheng

    出版 2004
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  10. 10
    Effective gene therapy in an authentic model of Tay-Sachs-related diseases

    Effective gene therapy in an authentic model of Tay-Sachs-related diseases 由 María Begoña Cachón-González, Susan Z. Wang, Andy G. Lynch, Robin J. Ziegler, Seng H. Cheng, Timothy M. Cox

    出版 2006
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  11. 11
    Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche

    Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche 由 Silvia Smaldone, Nicholas P. Clayton, Maria del Solar, Gemma Pascual, Seng H. Cheng, Bruce M. Wentworth, Mitchell B. Schaffler, Francesco Ramirez

    出版 2015
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  12. 12
    Correction of the Biochemical and Functional Deficits in Fabry Mice Following AAV8–mediated Hepatic Expression of α-galactosidase A

    Correction of the Biochemical and Functional Deficits in Fabry Mice Following AAV8–mediated Hepatic Expression of α-galactosidase A 由 Robin J. Ziegler, Maribeth Cherry, Christine M. Barbon, Chester Li, Scott D. Bercury, Donna Armentano, Robert J. Desnick, Seng H. Cheng

    出版 2006
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  13. 13
    Carbohydrate-remodelled acid α-glucosidase with higher affinity for the cation-independent mannose 6-phosphate receptor demonstrates improved delivery to muscles of Pompe mice

    Carbohydrate-remodelled acid α-glucosidase with higher affinity for the cation-independent mannose 6-phosphate receptor demonstrates improved delivery to muscles of Pompe mice 由 Yunxiang Zhu, Xuemei Li, Alison McVie‐Wylie, Canwen Jiang, Beth L. Thurberg, Nina Raben, Robert J. Mattaliano, Seng H. Cheng

    出版 2005
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  14. 14
    Binding and neutralizing anti-AAV antibodies: Detection and implications for rAAV-mediated gene therapy

    Binding and neutralizing anti-AAV antibodies: Detection and implications for rAAV-mediated gene therapy 由 Martin Schulz, David Lévy, Christos J. Petropoulos, George Bashirians, Ian Winburn, Matthias Mahn, Suryanarayan Somanathan, Seng H. Cheng, Barry J. Byrne

    出版 2023
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  15. 15
    Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

    Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis 由 Michael Chang, Jonathan D. Cooper, David E. Sleat, Seng H. Cheng, James C. Dodge, Marco A. Passini, Peter Lobel, Beverly L. Davidson

    出版 2008
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  16. 16
    Gene Transfer Corrects Acute GM2 Gangliosidosis—Potential Therapeutic Contribution of Perivascular Enzyme Flow

    Gene Transfer Corrects Acute GM2 Gangliosidosis—Potential Therapeutic Contribution of Perivascular Enzyme Flow 由 María Begoña Cachón-González, Susan Z. Wang, Rosamund McNair, Josephine Bradley, David Lunn, Robin J. Ziegler, Seng H. Cheng, Timothy M. Cox

    出版 2012
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  17. 17
    Silencing Mutant Huntingtin by Adeno-Associated Virus-Mediated RNA Interference Ameliorates Disease Manifestations in the YAC128 Mouse Model of Huntington's Disease

    Silencing Mutant Huntingtin by Adeno-Associated Virus-Mediated RNA Interference Ameliorates Disease Manifestations in the YAC128 Mouse Model of Huntington's Disease 由 Lisa M. Stanek, S. Pablo Sardi, Bryan Mastis, Amy R. Richards, Christopher M. Treleaven, Tatyana V. Taksir, Kuma Misra, Seng H. Cheng, Lamya S. Shihabuddin

    出版 2014
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  18. 18
    Systemic Administration of a Recombinant AAV1 Vector Encoding IGF-1 Improves Disease Manifestations in SMA Mice

    Systemic Administration of a Recombinant AAV1 Vector Encoding IGF-1 Improves Disease Manifestations in SMA Mice 由 Li‐Kai Tsai, Chien‐Lin Chen, Chen-Hung Ting, Sue Lin‐Chao, Wuh‐Liang Hwu, James C. Dodge, Marco A. Passini, Seng H. Cheng

    出版 2014
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  19. 19
    CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy

    CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy 由 Marco A. Passini, Jie Bu, Eric M. Roskelley, Amy M. Richards, S. Pablo Sardi, Catherine R. O’Riordan, K. Klinger, Lamya S. Shihabuddin, Seng H. Cheng

    出版 2010
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  20. 20
    Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan Syndrome

    Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan Syndrome 由 Jason R. Cook, Nicholas P. Clayton, Luca Carta, Josephine Galatioto, Emily Chiu, Silvia Smaldone, Carol A. Nelson, Seng H. Cheng, Bruce M. Wentworth, Francesco Ramirez

    出版 2015
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