Zoekresultaten - Sanjeev Shangary
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Targeting the MDM2-p53 Interaction for Cancer Therapy door Sanjeev Shangary, Shaomeng Wang
Gepubliceerd in 2008Revisão -
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Potent and Orally Active Small-Molecule Inhibitors of the MDM2−p53 Interaction door Shanghai Yu, Dongguang Qin, Sanjeev Shangary, Jianyong Chen, Guoping Wang, Ke Ding, Donna McEachern, Su Qiu, Zaneta Nikolovska‐Coleska, Rebecca S. Miller, Sunghyun Kang, Dajun Yang, Shaomeng Wang
Gepubliceerd in 2009Artigo -
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SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP door Jianfeng Lü, Longchuan Bai, Haiying Sun, Zaneta Nikolovska‐Coleska, Donna McEachern, Su Qiu, Rebecca S. Miller, Yi Han, Sanjeev Shangary, Yi Sun, Jennifer L. Meagher, Jeanne A. Stuckey, Shaomeng Wang
Gepubliceerd in 2008Artigo -
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Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer door Sanjeev Shangary, Ke Ding, Su Qiu, Zaneta Nikolovska‐Coleska, Joshua A. Bauer, Meilan Liu, Guoping Wang, Yipin Lu, Donna McEachern, Denzil Bernard, Carol R. Bradford, Thomas E. Carey, Shaomeng Wang
Gepubliceerd in 2008Artigo -
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Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition door Sanjeev Shangary, Dongguang Qin, Donna McEachern, Meilan Liu, Rebecca S. Miller, Su Qiu, Zaneta Nikolovska‐Coleska, Ke Ding, Guoping Wang, Jianyong Chen, Denzil Bernard, Jian Zhang, Yipin Lu, Qingyang Gu, Rajal B. Shah, Kenneth J. Pienta, Xiaolan Ling, Sunghyun Kang, Ming Guo, Yi Sun, Dajun Yang, Shaomeng Wang
Gepubliceerd in 2008Artigo -
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SAR405838: An Optimized Inhibitor of MDM2–p53 Interaction That Induces Complete and Durable Tumor Regression door Shaomeng Wang, Wei Sun, Yujun Zhao, Donna McEachern, Isabelle Meaux, Cédric Barrière, Jeanne A. Stuckey, Jennifer L. Meagher, Longchuan Bai, Liu Liu, C. Gianna Hoffman-Luca, Jianfeng Lü, Sanjeev Shangary, Shanghai Yu, Denzil Bernard, Angelo Aguilar, Odette Dos-Santos, Laurent Besret, S. Guérif, Pascal Pannier, Dimitri Gorge-Bernat, Laurent Debüssche
Gepubliceerd in 2014Artigo
Zoekinstrumenten:
Gerelateerde Onderwerpen
Biochemistry
Biology
Cancer research
Apoptosis
Mdm2
Cancer
Cell biology
Chemistry
Medicine
Function (biology)
Pharmacology
Programmed cell death
Cancer cell
Cancer therapy
Cell cycle
Cell cycle checkpoint
Cell growth
Genetics
Immunology
In vitro
Internal medicine
Small molecule
Bcl-2 family
Carcinogenesis
Caspase
Cell culture
Colorectal cancer
Gene
Gene knockdown
Growth inhibition