检索结果 - Samanthi A. Perera

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  1. 1
    Proapoptotic BH3-Only BCL-2 Family Protein BIM Connects Death Signaling from Epidermal Growth Factor Receptor Inhibition to the Mitochondrion

    Proapoptotic BH3-Only BCL-2 Family Protein BIM Connects Death Signaling from Epidermal Growth Factor Receptor Inhibition to the Mitochondrion 由 Jing Deng, Takeshi Shimamura, Samanthi A. Perera, Nicole E. Carlson, Dongpo Cai, Geoffrey I. Shapiro, Kwok‐Kin Wong, Anthony Letai

    出版 2007
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  2. 2
    A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit

    A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 由 Johnny E. Kopinja, Raquel Sevilla, Diane Levitan, David L. Dai, Amy Vanko, E. T. C. Spooner, Chris Ware, Robert Forget, Kun Hu, Astrid M. Kral, Peter Spacciapoli, Richard P. Kennan, Lata Jayaraman, Vincenzo Pucci, Samanthi A. Perera, Weisheng Zhang, Christian Fischer, Michael Hon‐Wah Lam

    出版 2017
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  3. 3
    Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in <i>In Vitro</i> and <i>In Vivo</i> Models of Non–Small Cell Lung Cancer

    Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in <i>In Vitro</i> and <i>In Vivo</i> Models of Non–Small Cell Lung Cancer 由 Takeshi Shimamura, Samanthi A. Perera, Kevin P. Foley, Jim Sang, Scott J. Rodig, Takayo Inoue, Liang Chen, Danan Li, Julián Carretero, Yuchen Li, Papiya Sinha, Christopher D. Carey, Christa L. Borgman, John-Paul Jimenez, Matthew Meyerson, Weiwen Ying, James Barsoum, Kwok‐Kin Wong, Geoffrey I. Shapiro

    出版 2012
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  4. 4
    Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

    Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers 由 Jeffrey A. Engelman, Liang Chen, Xiaohong Tan, Katherine Crosby, Alexander R. Guimarães, Rabi Upadhyay, Michel Maira, Kate McNamara, Samanthi A. Perera, Youngchul Song, Lucian R. Chirieac, Ramneet Kaur, Angela Lightbown, Jessica Simendinger, Timothy Li, Robert F. Padera, Carlos Garcı́a-Echeverrı́a, Ralph Weissleder, Umar Mahmood, Lewis C. Cantley, Kwok‐Kin Wong

    出版 2008
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  5. 5
    Mutations in BRAF and KRAS Converge on Activation of the Mitogen-Activated Protein Kinase Pathway in Lung Cancer Mouse Models

    Mutations in BRAF and KRAS Converge on Activation of the Mitogen-Activated Protein Kinase Pathway in Lung Cancer Mouse Models 由 Hongbin Ji, Zhenxiong Wang, Samanthi A. Perera, Danan Li, Mei‐Chih Liang, Sara Zaghlul, Kate McNamara, Liang Chen, Mitchell Albert, Yanping Sun, Ruqayyah Al-Hashem, Lucian R. Chirieac, Robert F. Padera, Roderick T. Bronson, Roman K. Thomas, Levi A. Garraway, Pasi A. Jänne, Bruce E. Johnson, Lynda Chin, Kwok‐Kin Wong

    出版 2007
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  6. 6
    HIF2α cooperates with RAS to promote lung tumorigenesis in mice

    HIF2α cooperates with RAS to promote lung tumorigenesis in mice 由 William Y. Kim, Samanthi A. Perera, Bing Zhou, Julián Carretero, Jen Jen Yeh, Samuel A. Heathcote, Autumn L. Jackson, Petros Nikolinakos, Beatriz Ospina, George N. Naumov, K. Brandstetter, Victor Weigman, Sara Zaghlul, D. Neil Hayes, Robert F. Padera, John V. Heymach, Andrew L. Kung, Norman E. Sharpless, William G. Kaelin, Kwok‐Kin Wong

    出版 2009
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  7. 7
    HER2 <sup>YVMA</sup> drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

    HER2 <sup>YVMA</sup> drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy 由 Samanthi A. Perera, Danan Li, Takeshi Shimamura, Maria Gabriela Raso, Hongbin Ji, Liang Chen, Christa L. Borgman, Sara Zaghlul, K. Brandstetter, Shigeto Kubo, Masaya Takahashi, Lucian R. Chirieac, Robert F. Padera, Roderick T. Bronson, Geoffrey I. Shapiro, Heidi Greulich, Matthew Meyerson, Ulrich Guertler, Pilar Garin Chesa, Flavio Solca, Ignacio I. Wistuba, Kwok‐Kin Wong

    出版 2009
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  8. 8
    Hsp90 Inhibition Suppresses Mutant EGFR-T790M Signaling and Overcomes Kinase Inhibitor Resistance

    Hsp90 Inhibition Suppresses Mutant EGFR-T790M Signaling and Overcomes Kinase Inhibitor Resistance 由 Takeshi Shimamura, Danan Li, Hongbin Ji, Henry J. Haringsma, Elizabeth Liniker, Christa L. Borgman, April M. Lowell, Yuko Minami, Kate McNamara, Samanthi A. Perera, Sara Zaghlul, Roman K. Thomas, Heidi Greulich, Susumu Kobayashi, Lucian R. Chirieac, Robert F. Padera, Shigeto Kubo, Masaya Takahashi, Daniel G. Tenen, Matthew Meyerson, Kwok‐Kin Wong, Geoffrey I. Shapiro

    出版 2008
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  9. 9
    Bronchial and Peripheral Murine Lung Carcinomas Induced by T790M-L858R Mutant EGFR Respond to HKI-272 and Rapamycin Combination Therapy

    Bronchial and Peripheral Murine Lung Carcinomas Induced by T790M-L858R Mutant EGFR Respond to HKI-272 and Rapamycin Combination Therapy 由 Danan Li, Takeshi Shimamura, Hongbin Ji, Liang Chen, Henry J. Haringsma, Kate McNamara, Mei‐Chih Liang, Samanthi A. Perera, Sara Zaghlul, Christa L. Borgman, Shigeto Kubo, Masaya Takahashi, Yanping Sun, Lucian R. Chirieac, Robert F. Padera, Neal I. Lindeman, Pasi A. Jänne, Roman K. Thomas, Matthew Meyerson, Michael J. Eck, Jeffrey A. Engelman, Geoffrey I. Shapiro, Kwok‐Kin Wong

    出版 2007
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  10. 10
    Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer

    Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer 由 Martin L. Sos, Stefanie Fischer, Roland T. Ullrich, Martin Peifer, Johannes M. Heuckmann, Mirjam Koker, Stefanie Heynck, Isabel Stückrath, Jonathan M. Weiss, Florian Fischer, Kathrin Michel, Aviva Goel, Lucía Regales, Katerina Politi, Samanthi A. Perera, Matthäus Getlik, Lukas C. Heukamp, Sascha Ansén, Thomas Zander, Rameen Beroukhim, Hamid Kashkar, Kevan M. Shokat, William R. Sellers, Daniel Rauh, Christine Orr, Klaus P. Hoeflich, Lori S. Friedman, Kwok‐Kin Wong, William Pao, Roman K. Thomas

    出版 2009
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