Search Results - Sacha Spelier

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  1. 1
    Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

    Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy by Else Driehuis, Sacha Spelier, Irati Beltrán Hernández, Remco de Bree, Stefan M. Willems, Hans Clevers, Sabrina Oliveira

    Published 2019
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  2. 2
    Readthrough compounds for nonsense mutations: bridging the translational gap

    Readthrough compounds for nonsense mutations: bridging the translational gap by Sacha Spelier, Eveline P.M. van Doorn, Cornelis K. van der Ent, Jeffrey M. Beekman, Martijn Koppens

    Published 2023
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  3. 3
    Use of 2,6-diaminopurine as a potent suppressor of UGA premature stop codons in cystic fibrosis

    Use of 2,6-diaminopurine as a potent suppressor of UGA premature stop codons in cystic fibrosis by Catherine Leroy, Sacha Spelier, Nadège Charlène Essonghé, Virginie Poix, Rebekah Kong, Patrick Gizzi, Claire Bourban, Séverine Amand, Christine Bailly, Romain Guilbert, David Hannebique, Philippe Persoons, Gwenaëlle Arhant, Anne Prévötat, Philippe Reix, D. Hubert, M. Gérardin, Mathias Chamaillard, Natalia Prevarskaya, Sylvie Rebuffat, George Shapovalov, Jeffrey M. Beekman, Fabrice Lejeune

    Published 2023
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  4. 4
    Mutation-specific reporter for optimization and enrichment of prime editing

    Mutation-specific reporter for optimization and enrichment of prime editing by Imre F. Schene, Indi P. Joore, Jan H. L. Baijens, Remi Stevelink, Gautam Kok, Sawsan Shehata, Eveline F. Ilcken, E. C. M. Nieuwenhuis, Dian Bolhuis, R. C. M. van Rees, Sacha Spelier, Hubert P. J. van der Doef, Jeffrey M. Beekman, Roderick H.J. Houwen, Edward E. S. Nieuwenhuis, Sabine A. Fuchs

    Published 2022
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  5. 5
    Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

    Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia by Gimano D. Amatngalim, Lisa W. Rodenburg, Bente L. Aalbers, Henriette H. M. Raeven, Ellen Aarts, Dounia Sarhane, Sacha Spelier, Juliet Lefferts, Iris A. L. Silva, Wilco Nijenhuis, Sacha Vrendenbarg, Evelien Kruisselbrink, Jesse E. Brunsveld, Cornelis M. van Drunen, Sabine Michel, Karin M. de Winter–de Groot, Harry Heijerman, Lukas C. Kapitein, Margarida D. Amaral, Cornelis K. van der Ent, Jeffrey M. Beekman

    Published 2022
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  6. 6
    FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

    FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes by Eyleen de Poel, Sacha Spelier, Marne C. Hagemeijer, Peter van Mourik, S.W.F. Suen, Annelotte M. Vonk, Jesse E. Brunsveld, G.N. Ithakisiou, Evelien Kruisselbrink, Hugo Oppelaar, Gitte Berkers, Kate Groot, Sabine Heida-Michel, S.R. Jans, H. van Panhuis, Marleen Bakker, Renske van der Meer, Jolt Roukema, Edward Dompeling, Els J.M. Weersink, Gerard H. Koppelman, Antoni R. Blaazer, J.E. Muijlwijk-Koezen, Cornelis K. van der Ent, Jeffrey M. Beekman

    Published 2023
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  7. 7
    Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy

    Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy by Else Driehuis, Sigrid Kolders, Sacha Spelier, Kadi Lõhmussaar, Stefan M. Willems, Lot A. Devriese, Remco de Bree, Emma J. de Ruiter, Jeroen Korving, Harry Begthel, Johan H. van Es, Veerle Geurts, Gui-Wei He, Richard H. van Jaarsveld, Rurika Oka, Mauro J. Muraro, Judith Vivié, Maurice M.J.M. Zandvliet, Antoni P. A. Hendrickx, Nino Iakobachvili, Priya Sridevi, Onno Kranenburg, Ruben van Boxtel, Geert J.P.L. Kops, David A. Tuveson, Peter J. Peters, Alexander van Oudenaarden, Hans Clevers

    Published 2019
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