Αποτελέσματα αναζήτησης - Roman Yelensky
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Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors από Jennifer J. Wheler, Johnique T. Atkins, Filip Janků, Stacy L. Moulder, Philip J. Stephens, Roman Yelensky, Vicente Valero, Vincent A. Miller, Razelle Kurzrock, Funda Meric‐Bernstam
Έκδοση 2016Artigo -
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Comprehensive genomic profiling of epithelial ovarian cancer by next generation sequencing-based diagnostic assay reveals new routes to targeted therapies από Jeffrey S. Ross, Siraj M. Ali, K. Wang, Gary A. Palmer, Roman Yelensky, Doron Lipson, V.A. Miller, Deborah A. Zajchowski, Laura K. Shawver, Philip J. Stephens
Έκδοση 2013Artigo -
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Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib από Victor Wong, Dean C. Pavlick, Timothy J. Brennan, Roman Yelensky, John R. Crawford, Jeffrey S. Ross, Vincent A. Miller, Denise Malicki, Philip J. Stephens, Siraj M. Ali, Hyunah Ahn
Έκδοση 2015Carta -
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A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal από James Sun, Yuting He, Eric M. Sanford, Meagan Montesion, Garrett M. Frampton, Stéphane Vignot, Jean‐Charles Soria, Jeffrey S. Ross, Vincent A. Miller, Phil Stephens, Doron Lipson, Roman Yelensky
Έκδοση 2018Artigo -
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Biological and clinical evidence for somatic mutations in <i>BRCA1</i> and <i>BRCA2</i> as predictive markers for olaparib response in high-grade serous ovarian cancers in the main... από Brian Dougherty, Zhongwu Lai, Darren Hodgson, Maria Orr, Matthew Hawryluk, James Sun, Roman Yelensky, Stuart Spencer, Jane Robertson, Tony W. Ho, Anitra Fielding, Jonathan A. Ledermann, J. Carl Barrett
Έκδοση 2017Artigo -
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Oncogenic Alterations in <i>ERBB2/HER2</i> Represent Potential Therapeutic Targets Across Tumors From Diverse Anatomic Sites of Origin από Juliann Chmielecki, Jeffrey S. Ross, Kai Wang, Garrett M. Frampton, Gary A. Palmer, Siraj M. Ali, Norma Alonzo Palma, Deborah Morosini, Vincent A. Miller, Roman Yelensky, Doron Lipson, Philip J. Stephens
Έκδοση 2014Artigo -
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A Targeted Next-Generation Sequencing Assay Detects a High Frequency of Therapeutically Targetable Alterations in Primary and Metastatic Breast Cancers: Implications for Clinical P... από Neil Vasan, Roman Yelensky, Kai Wang, Stacy Moulder, Hannah Dzimitrowicz, Rony Avritscher, Baliang Wang, Yun Wu, Maureen Cronin, Gary A. Palmer, W. Fraser Symmans, Vincent A. Miller, Philip Stephens, Lajos Pusztai
Έκδοση 2014Artigo -
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D538G Mutation in Estrogen Receptor-α: A Novel Mechanism for Acquired Endocrine Resistance in Breast Cancer από Keren Merenbakh-Lamin, Noa Ben-Baruch, Adva Yeheskel, Addie Dvir, Lior Soussan‐Gutman, Rinath Jeselsohn, Roman Yelensky, Myles Brown, Vincent A. Miller, David Sarid, Shulamith Rizel, Baruch Klein, Tamar Rubinek, Ido Wolf
Έκδοση 2013Artigo -
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Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway από Jennifer J. Wheler, Stacy Moulder, Aung Naing, Filip Janků, Sarina A. Piha‐Paul, Gerald S. Falchook, Ralph Zinner, Apostolia M. Tsimberidou, Siqing Fu, David S. Hong, Johnique T. Atkins, Roman Yelensky, Philip J. Stephens, Razelle Kurzrock
Έκδοση 2014Artigo -
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Genomic Profiling of Advanced-Stage, Metaplastic Breast Carcinoma by Next-Generation Sequencing Reveals Frequent, Targetable Genomic Abnormalities and Potential New Treatment Optio... από Jeffrey S. Ross, Sunil Badve, Kai Wang, Christine E. Sheehan, Ann Boguniewicz, Geoff Otto, Roman Yelensky, Doron Lipson, Siraj M. Ali, Deborah Morosini, Juliann Chliemlecki, Julia A. Elvin, Vincent A. Miller, Philip J. Stephens
Έκδοση 2015Artigo -
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Comprehensive Genomic Profiling of Advanced Esophageal Squamous Cell Carcinomas and Esophageal Adenocarcinomas Reveals Similarities and Differences από Kai Wang, Adrienne Johnson, Siraj M. Ali, Samuel J. Klempner, Tanios Bekaii‐Saab, Jeffrey Vacirca, Depinder Khaira, Roman Yelensky, Juliann Chmielecki, Julia A. Elvin, Doron Lipson, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross
Έκδοση 2015Artigo -
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Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity από Himisha Beltran, Roman Yelensky, Garrett M. Frampton, Kyung Park, Sean R. Downing, Theresa Y. MacDonald, Mirna Jarosz, Doron Lipson, Scott T. Tagawa, David M. Nanus, Philip J. Stephens, Juan Miguel Mosquera, Maureen Cronin, Mark A. Rubin
Έκδοση 2012Artigo -
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Next-Generation Sequencing Reveals High Concordance of Recurrent Somatic Alterations Between Primary Tumor and Metastases From Patients With Non–Small-Cell Lung Cancer από Stéphane Vignot, Garrett M. Frampton, Jean‐Charles Soria, Roman Yelensky, Frédéric Commo, Christian Brambilla, Gary A. Palmer, Denis Moro‐Sibilot, Jeffrey S. Ross, Maureen Cronin, Fabrice André, Philip J. Stephens, Vladimir Lazar, Vincent A. Miller, Élisabeth Brambilla
Έκδοση 2013Artigo -
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Relapsed Classic E-Cadherin (<i>CDH1</i>)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of<i>HER2</i>(<i>ERBB2</i>) Gene Mutations από Jeffrey S. Ross, Kai Wang, Christine E. Sheehan, Ann Boguniewicz, Geoff Otto, Sean R. Downing, James Sun, Jie He, John A. Curran, Siraj M. Ali, Roman Yelensky, Doron Lipson, Gary A. Palmer, Vincent A. Miller, Philip J. Stephens
Έκδοση 2013Artigo -
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Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer από Jeffrey S. Ross, K Wang, Osama Elkadi, Ashley J. Tarasen, Llewelyn Foulke, Christine E. Sheehan, Geoff Otto, Gary A. Palmer, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Siraj M. Ali, Julia A. Elvin, Deborah Morosini, V.A. Miller, Philip J. Stephens
Έκδοση 2014Artigo -
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Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations από Jeffrey S. Ross, Kai Wang, Depinder Khaira, Siraj M. Ali, Huge A.G. Fisher, Badar M. Mian, Tipu Nazeer, Julia A. Elvin, Norma Alonzo Palma, Roman Yelensky, Doron Lipson, Vincent A. Miller, Philip J. Stephens, Vivek Subbiah, Sumanta K. Pal
Έκδοση 2015Artigo -
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Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site από Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Geoff Otto, Emily White, Kiel Iwanik, Gary A. Palmer, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Rachel Erlich, Andrew Rankin, Siraj M. Ali, Julia A. Elvin, Deborah Morosini, Vincent A. Miller, Philip J. Stephens
Έκδοση 2015Artigo -
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Comprehensive Genomic Profiling of Pancreatic Acinar Cell Carcinomas Identifies Recurrent <i>RAF</i> Fusions and Frequent Inactivation of DNA Repair Genes από Juliann Chmielecki, Katherine E. Hutchinson, Garrett M. Frampton, Zachary R. Chalmers, Adrienne Johnson, Chanjuan Shi, Julia A. Elvin, Siraj M. Ali, Jeffrey S. Ross, Olca Baştürk, Sohail Balasubramanian, Doron Lipson, Roman Yelensky, William Pao, Vincent A. Miller, David S. Klimstra, Philip J. Stephens
Έκδοση 2014Artigo
Εργαλεία αναζήτησης:
Σχετικά θέματα
Biology
Medicine
Cancer
Cancer research
Genetics
Internal medicine
Gene
Oncology
Breast cancer
PI3K/AKT/mTOR pathway
Colorectal cancer
Exon
Pathology
PTEN
Apoptosis
CDKN2A
Genome
KRAS
Mutation
Targeted therapy
Copy-number variation
Bioinformatics
Fusion gene
Lung cancer
Adenocarcinoma
Immunology
Biochemistry
Copy number analysis
Signal transduction
ARID1A