Search Results - Richard C. Chao

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  1. 1
    Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine.

    Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. by Richard C. Chao, Waris Khan, Y A Hannun

    Published 1992
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  2. 2
    A phase 2 study of mocetinostat, a histone deacetylase inhibitor, in relapsed or refractory lymphoma

    A phase 2 study of mocetinostat, a histone deacetylase inhibitor, in relapsed or refractory lymphoma by Connie Lee Batlevi, Michael Crump, Charalambos Andreadis, David A. Rizzieri, Sarit Assouline, Susan Fox, Richard H. C. Van Der Jagt, Amanda Copeland, Diane Potvin, Richard C. Chao, Anas Younes

    Published 2017
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  3. 3
    Phase II study of continuous daily sunitinib dosing in patients with previously treated advanced non-small cell lung cancer

    Phase II study of continuous daily sunitinib dosing in patients with previously treated advanced non-small cell lung cancer by Silvia Novello, Giorgio V. Scagliotti, Rafael Rosell, Mark A. Socinski, Julie R. Brahmer, J. Atkins, Cinta Pallarés, R Burgess, L. Tye, Paulina Selaru, Edward Wang, Richard C. Chao, Ramaswamy Govindan

    Published 2009
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  4. 4
    Multicenter, Phase II Trial of Sunitinib in Previously Treated, Advanced Non–Small-Cell Lung Cancer

    Multicenter, Phase II Trial of Sunitinib in Previously Treated, Advanced Non–Small-Cell Lung Cancer by Mark A. Socinski, Silvia Novello, Julie R. Brahmer, Rafael Rosell, José Miguel Sánchez, Chandra P. Belani, Ramaswamy Govindan, James N. Atkins, Heidi H. Gillenwater, Cinta Pallarés, L. Tye, Paulina Selaru, Richard C. Chao, Giorgio V. Scagliotti

    Published 2008
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  5. 5
    First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced <i>KRAS</i><sup><i>G12C</i></sup> Solid Tumors (KRYSTAL-1)

    First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced <i>KRAS</i><sup><i>G12C</i></sup> Solid Tumors (KRYSTAL-1) by Sai‐Hong Ignatius Ou, Pasi A. Jänne, Ticiana Leal, Igor I. Rybkin, Joshua K. Sabari, Minal Barve, Lyudmila Bazhenova, Melissa L. Johnson, Karen Velastegui, Cornelius Cilliers, James G. Christensen, Xiaohong Yan, Richard C. Chao, Kyriakos P. Papadopoulos

    Published 2022
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  6. 6
    A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC)

    A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC) by Harry J.M. Groen, Mark A. Socinski, Francesco Grossi, Erzsébet Juhász, Cesare Gridelli, Paul Baas, Charles Butts, Ewa Chmielowska, Tiziana Usari, Paulina Selaru, Charles S. Harmon, James A. Williams, Feng Gao, L. Tye, Richard C. Chao, George R. Blumenschein

    Published 2013
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  7. 7
    Early Changes in Circulating Cell-Free <i>KRAS</i> G12C Predict Response to Adagrasib in KRAS Mutant Non–Small Cell Lung Cancer Patients

    Early Changes in Circulating Cell-Free <i>KRAS</i> G12C Predict Response to Adagrasib in KRAS Mutant Non–Small Cell Lung Cancer Patients by Cloud P. Paweletz, Grace A. Heavey, Yanan Kuang, Emily Durlacher, Thian Kheoh, Richard C. Chao, Alexander I. Spira, Konstantinos Leventakos, Melissa L. Johnson, Sai‐Hong Ignatius Ou, Gregory J. Riely, Kenna Anderes, Wenjing Yang, James G. Christensen, Pasi A. Jänne

    Published 2023
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  8. 8
    First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors

    First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors by Todd M. Bauer, Byoung Chul Cho, Rebecca S. Heist, Lyudmila Bazhenova, Theresa L. Werner, Sanjay Goel, Dong‐Wan Kim, Douglas Adkins, Richard D. Carvajal, Ajjai Alva, Keith D. Eaton, Judy Wang, Yong Liu, Xiaohong Yan, Jamie Christensen, Saskia Neuteboom, Richard C. Chao, Shubham Pant

    Published 2022
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  9. 9
    Phase II Trial of Sunitinib in Patients With Metastatic Colorectal Cancer After Failure of Standard Therapy

    Phase II Trial of Sunitinib in Patients With Metastatic Colorectal Cancer After Failure of Standard Therapy by Leonard B. Saltz, Lee S. Rosen, John L. Marshall, Robert J. Belt, Herbert I. Hurwitz, Sabine Eckhardt, Emily K. Bergsland, Daniel G. Haller, A. Craig Lockhart, Caio M. Rocha Lima, Xin Huang, Samuel E. DePrimo, Edna Chow‐Maneval, Richard C. Chao, Heinz Josef Lenz

    Published 2007
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  10. 10
    Sunitinib Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer: A Phase III Trial

    Sunitinib Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer: A Phase III Trial by Giorgio V. Scagliotti, Maciej Krzakowski, Aleksandra Szczęsna, János Strausz, А. Н. Махсон, Martin Reck, Rafal Wierzbicki, István Albert, Michael Thomas, José Elias Miziara, Zsolt Pápai, Nina Karaseva, Sumitra Thongprasert, E. Dalmau, Joachim von Pawel, Ke Zhang, Paulina Selaru, L. Tye, Richard C. Chao, Ramaswamy Govindan

    Published 2012
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  11. 11
    Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors

    Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors by Éric Raymond, Laëtitia Dahan, Jean‐Luc Raoul, Yung‐Jue Bang, Ivan Borbath, Catherine Lombard‐Bohas, Juan W. Valle, Peter Metrakos, Denis Smith, Aaron I. Vinik, Jen‐Shi Chen, Dieter Hörsch, Pascal Hammel, Bertram Wiedenmann, Eric Van Cutsem, Shem Patyna, Dongrui R. Lu, C. Blanckmeister, Richard C. Chao, Philippe Ruszniewski

    Published 2011
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  12. 12
    Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes

    Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes by Petros Grivas, Amir Mortazavi, Joel Picus, Noah M. Hahn, Matthew I. Milowsky, Lowell L. Hart, Ajjai Alva, Joaquim Bellmunt, Sumanta K. Pal, Richard Bambury, Peter H. O’Donnell, Sumati Gupta, Elizabeth A. Guancial, Guru Sonpavde, Demiana Faltaos, Diane Potvin, James G. Christensen, Richard C. Chao, Jonathan E. Rosenberg

    Published 2018
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  13. 13
    KRYSTAL-1: Activity and Safety of Adagrasib (MRTX849) in Advanced/ Metastatic Non–Small-Cell Lung Cancer (NSCLC) Harboring KRAS G12C Mutation

    KRYSTAL-1: Activity and Safety of Adagrasib (MRTX849) in Advanced/ Metastatic Non–Small-Cell Lung Cancer (NSCLC) Harboring KRAS G12C Mutation by Pasi A. Jänne, Igor I. Rybkin, Alexander I. Spira, Gregory J. Riely, K. Papadopoulos, Joshua K. Sabari, Melissa L. Johnson, Rebecca S. Heist, Lyudmila Bazhenova, Minal Barve, J.M. Pacheco, Ticiana Leal, Karen Velastegui, Crystal Cornelius, Peter Olson, James G. Christensen, Thian Kheoh, Richard C. Chao, S.‐H.I. Ou

    Published 2020
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  14. 14
    Adagrasib in Non–Small-Cell Lung Cancer Harboring a <i> KRAS <sup>G12C</sup> </i> Mutation

    Adagrasib in Non–Small-Cell Lung Cancer Harboring a <i> KRAS <sup>G12C</sup> </i> Mutation by Pasi A. Jänne, Gregory J. Riely, Shirish M. Gadgeel, Rebecca S. Heist, Sai‐Hong Ignatius Ou, Jose M. Pacheco, Melissa L. Johnson, Joshua K. Sabari, Konstantinos Leventakos, Edwin Yau, Lyudmila Bazhenova, Marcelo V. Negrão, Nathan A. Pennell, Jun Zhang, Kenna Anderes, Hirak Der‐Torossian, Thian Kheoh, Karen Velastegui, Xiaohong Yan, James G. Christensen, Richard C. Chao, Alexander I. Spira

    Published 2022
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  15. 15
    Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1

    Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1 by Anne Slavotinek, Sergio E. Baranzini, Denny Schanze, Cassandre Labelle‐Dumais, Kieran M. Short, Richard C. Chao, Mani Yavi, Emilia K. Bijlsma, Catherine Chu, Stacy L. Musone, Amanda Wheatley, Pui‐Yan Kwok, Sandra L. Marles, J. P. Fryns, A. Murat Maga, Mohamed G. Hassan, Douglas B. Gould, Lohith Madireddy, Chumei Li, Timothy C. Cox, Ian Smyth, Albert E. Chudley, Martin Zenker

    Published 2011
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  16. 16
    Comparative Pathology of Nerve Sheath Tumors in Mouse Models and Humans

    Comparative Pathology of Nerve Sheath Tumors in Mouse Models and Humans by Anat Stemmer‐Rachamimov, David N. Louis, G. Petur Nielsen, Cristina R. Antonescu, Alexander D. Borowsky, Roderick T. Bronson, Dennis K. Burns, Pascale Cervera, Margaret E. McLaughlin, Guido Reifenberger, Michael C. Schmale, Mia MacCollin, Richard C. Chao, Karen Cichowski, Michel Kalamarides, Shanta M. Messerli, Andrea I. McClatchey, Michiko Niwa‐Kawakita, Nancy Ratner, Karlyne M. Reilly, Yuan Zhu, Marco Giovannini

    Published 2004
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  17. 17
    Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring <i>MET</i> Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models

    Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring <i>MET</i> Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors... by Lars D. Engstrom, Ruth Aranda, Matthew Lee, Elizabeth A. Tovar, Curt J. Essenburg, Zachary Madaj, Harrah Chiang, David M. Briere, Jill Hallin, Pedro P. López‐Casas, Natalia Baños, Camino Menéndez, Manuel Hidalgo, Vanessa Tassell, Richard C. Chao, Darya Chudova, Richard B. Lanman, Peter Olson, Lyudmila Bazhenova, Sandip Pravin Patel, Carrie R. Graveel, Mizuki Nishino, Geoffrey I. Shapiro, Nir Peled, Mark M. Awad, Pasi A. Jänne, James G. Christensen

    Published 2017
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  18. 18
    The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients

    The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients by Jill Hallin, Lars D. Engstrom, Lauren Hargis, Andrew Calinisan, Ruth Aranda, David M. Briere, Niranjan Sudhakar, Vickie Bowcut, Brian R. Baer, Joshua A. Ballard, Michael Burkard, Jay B. Fell, John P. Fischer, Guy Vigers, Jenny Y. Xue, Sole Gatto, Julio Fernandez-Banet, Adam Pavlı́ček, Karen Velastagui, Richard C. Chao, Jeremy Barton, Mariaelena Pierobon, Elisa Baldelli, Emanuel F. Patricoin, Douglas P. Cassidy, Matthew A. Marx, Igor I. Rybkin, Melissa L. Johnson, Sai‐Hong Ignatius Ou, Piro Lito, Kyriakos P. Papadopoulos, Pasi A. Jänne, Peter Olson, James G. Christensen

    Published 2019
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  19. 19
    Institutional implementation of clinical tumor profiling on an unselected cancer population

    Institutional implementation of clinical tumor profiling on an unselected cancer population by Lynette M. Sholl, T. Khanh, Priyanka Shivdasani, Ethan Cerami, Adrian M. Dubuc, Frank C. Kuo, Elizabeth P. Garcia, Yonghui Jia, Phani K. Davineni, Ryan Abo, Trevor J. Pugh, Paul Van Hummelen, Aaron R. Thorner, Matthew D. Ducar, Alice H. Berger, Mizuki Nishino, Katherine A. Janeway, Alanna J. Church, Marian H. Harris, Lauren L. Ritterhouse, Joshua D. Campbell, Vanesa Rojas‐Rudilla, Azra H. Ligon, Shakti Ramkissoon, James M. Cleary, Ursula A. Matulonis, Geoffrey R. Oxnard, Richard C. Chao, Vanessa Tassell, James G. Christensen, William C. Hahn, Philip W. Kantoff, David J. Kwiatkowski, Bruce E. Johnson, Matthew Meyerson, Levi A. Garraway, Geoffrey I. Shapiro, Barrett J. Rollins, Neal I. Lindeman, Laura E. MacConaill

    Published 2016
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