Kết quả tìm kiếm - Rainer Machauer

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  1. 1
    Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach

    Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach Bằng Henrik Möbitz, Rainer Machauer, Philipp Holzer, Andrea Vaupel, Frédéric Stauffer, Christian Ragot, Giorgio Caravatti, Clemens Scheufler, César Fernández Fernández, Ulrich Hommel, Ralph Tiedt, Kim S. Beyer, Chao Chen, Hugh Zhu, Christoph Gaul

    Được phát hành 2017
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    Artigo
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  2. 2
    A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice

    A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice Bằng Ulf Neumann, Heinrich Rueeger, Rainer Machauer, Siem Jacob Veenstra, Rainer Lueoend, Marina Tintelnot‐Blomley, Grit Laue, Karen Beltz, Barbara Vogg, Peter Schmid, Wilfried Frieauff, Derya R. Shimshek, Matthias Staufenbiel, Laura H. Jacobson

    Được phát hành 2015
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    Artigo
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  3. 3
    Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach

    Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach Bằng Chao Chen, Hugh Zhu, Frédéric Stauffer, Giorgio Caravatti, Susanne Vollmer, Rainer Machauer, Philipp Holzer, Henrik Möbitz, Clemens Scheufler, Martin Klumpp, Ralph Tiedt, Kim S. Beyer, Keith Calkins, Daniel Guthy, Michael Kiffe, Jeff Zhang, Christoph Gaul

    Được phát hành 2016
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    Artigo
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  4. 4
    Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice

    Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice Bằng Derya R. Shimshek, Laura H. Jacobson, Carine Kolly, Natasa Zamurovic, Kamal K. Balavenkatraman, Laurent Morawiec, Robert Kreutzer, Juliane Schelle, Mathias Jucker, Barbara Bertschi, Diethilde Theil, Annabelle Heier, Karine Bigot, Karen Beltz, Rainer Machauer, Irena Brzak, Ludovic Perrot, Ulf Neumann

    Được phát hành 2016
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    Artigo
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  5. 5
    The <scp>BACE</scp> ‐1 inhibitor <scp>CNP</scp> 520 for prevention trials in Alzheimer's disease

    The <scp>BACE</scp> ‐1 inhibitor <scp>CNP</scp> 520 for prevention trials in Alzheimer's disease Bằng Ulf Neumann, Mike Ufer, Laura H. Jacobson, Marie‐Laure Rouzade‐Dominguez, Gunilla Huledal, Carine Kolly, Rainer M. Lüönd, Rainer Machauer, Siem J. Veenstra, Konstanze Hurth, Heinrich Rueeger, Marina Tintelnot‐Blomley, Matthias Staufenbiel, Derya R. Shimshek, Ludovic Perrot, Wilfried Frieauff, Valérie Dubost, Hilmar Schiller, Barbara Vogg, Karen Beltz, Alexandre Avraméas, Sandrine Kretz, Nicole Pezous, Jean‐Michel Rondeau, Nicolau Beckmann, Andreas Hartmann, Stefan Viktor Vormfelde, Olivier J. David, Bruno Galli, Rita Ramos, Ana Graf, Cristina López López

    Được phát hành 2018
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    Artigo
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  6. 6
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo Bằng Kenji Namoto, Clara Baader, Vanessa Orsini, Alexandro Landshammer, Eva Breuer, Kieu Trinh Dinh, Rosemarie Ungricht, Monika Pikiolek, Stéphane Laurent, Bo Lü, Alexandra Aebi, Katharina Schönberger, Eric Vangrevelinghe, Olivera Evrova, Tianliang Sun, Stefano Annunziato, Julie Lachal, Emily Redmond, Louis Wang, Kristie Wetzel, Paola Capodieci, Jonathan Turner, Gabi Schutzius, Vincent Unterreiner, Markus Trunzer, Nicole Buschmann, Dirk Behnke, Rainer Machauer, Clemens Scheufler, Christian N. Parker, Magali Ferro, Armelle Grevot, Armin Beyerbach, Wei‐Yu Lu, Stuart J. Forbes, Jürgen Wagner, Tewis Bouwmeester, Jun Liu, Bindi Sohal, Sukhdeep K. Sahambi, Linda E. Greenbaum, Felix Lohmann, Philipp S. Hoppe, Feng Cong, Andreas W. Sailer, Heinz Ruffner, Ralf Glatthar, Bostjan Humar, Pierre–Alain Clavien, Michael T. Dill, Elizabeth George, Jürgen Maibaum, Prisca Liberali, Jan S. Tchorz

    Được phát hành 2024
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    Artigo
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