Výsledky vyhledávání - Philip J. Stephens

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  1. 1
    Protein control of iron-sulfur cluster redox potentials.

    Protein control of iron-sulfur cluster redox potentials. Autor Ralf Langen, Greg Jensen, U. Jacob, Philip J. Stephens, Arieh Warshel

    Vydáno 1992
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  2. 2
    Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

    Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion Autor Lee A. Albacker, Jeremy Wu, Peter Smith, Markus Warmuth, Philip J. Stephens, Ping Zhu, Lihua Yu, Juliann Chmielecki

    Vydáno 2017
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  3. 3
    A large genome center's improvements to the Illumina sequencing system

    A large genome center's improvements to the Illumina sequencing system Autor Michael A. Quail, Iwanka Kozarewa, Frances J.D. Smith, Aylwyn Scally, Philip J. Stephens, Richard Durbin, Harold Swerdlow, Daniel J. Turner

    Vydáno 2008
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  4. 4
    Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers

    Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers Autor Aaron M. Goodman, Shumei Kato, Lyudmila Bazhenova, Sandip Pravin Patel, Garrett M. Frampton, Vincent A. Miller, Philip J. Stephens, Gregory A. Daniels, Razelle Kurzrock

    Vydáno 2017
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  5. 5
    Genomic landscape of advanced basal cell carcinoma: Implications for precision treatment with targeted and immune therapies

    Genomic landscape of advanced basal cell carcinoma: Implications for precision treatment with targeted and immune therapies Autor Aaron M. Goodman, Shumei Kato, Philip R. Cohen, Amélie Boichard, Garrett M. Frampton, Vincent A. Miller, Philip J. Stephens, Gregory A. Daniels, Razelle Kurzrock

    Vydáno 2017
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  6. 6
    Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

    Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing Autor Peter J. Campbell, Erin Pleasance, Philip J. Stephens, Ed Dicks, Richard Rance, Ian Goodhead, George Follows, Anthony R. Green, P. Andy Futreal, Michael R. Stratton

    Vydáno 2008
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  7. 7
    Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors

    Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors Autor Jennifer J. Wheler, Johnique T. Atkins, Filip Janků, Stacy L. Moulder, Philip J. Stephens, Roman Yelensky, Vicente Valero, Vincent A. Miller, Razelle Kurzrock, Funda Meric‐Bernstam

    Vydáno 2016
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  8. 8
    Identification of a Novel HIP1-ALK Fusion Variant in Non–Small-Cell Lung Cancer (NSCLC) and Discovery of ALK I1171 (I1171N/S) Mutations in Two ALK-Rearranged NSCLC Patients with Resistance to Alectinib

    Identification of a Novel HIP1-ALK Fusion Variant in Non–Small-Cell Lung Cancer (NSCLC) and Discovery of ALK I1171 (I1171N/S) Mutations in Two ALK-Rearranged NSCLC Patients with Re... Autor Sai‐Hong Ignatius Ou, Samuel J. Klempner, Joel Greenbowe, Michele C. Azada, Alexa B. Schrock, Siraj M. Ali, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller

    Vydáno 2014
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  9. 9
    Comprehensive genomic profiling of epithelial ovarian cancer by next generation sequencing-based diagnostic assay reveals new routes to targeted therapies

    Comprehensive genomic profiling of epithelial ovarian cancer by next generation sequencing-based diagnostic assay reveals new routes to targeted therapies Autor Jeffrey S. Ross, Siraj M. Ali, K. Wang, Gary A. Palmer, Roman Yelensky, Doron Lipson, V.A. Miller, Deborah A. Zajchowski, Laura K. Shawver, Philip J. Stephens

    Vydáno 2013
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  10. 10
    Emergence of novel and dominant acquired EGFR solvent-front mutations at Gly796 (G796S/R) together with C797S/G and L792F/H mutations in one EGFR (L858R/T790M) NSCLC patient who progressed on osimertinib

    Emergence of novel and dominant acquired EGFR solvent-front mutations at Gly796 (G796S/R) together with C797S/G and L792F/H mutations in one EGFR (L858R/T790M) NSCLC patient who pr... Autor Sai‐Hong Ignatius Ou, Jean Cui, Alexa B. Schrock, Michael E. Goldberg, Viola W. Zhu, Lee A. Albacker, Philip J. Stephens, Vincent A. Miller, Siraj M. Ali

    Vydáno 2017
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  11. 11
    Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions

    Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions Autor Christine M. Lovly, Abha A. Gupta, Doron Lipson, Geoff Otto, Tina Brennan, Catherine T. Chung, Scott C. Borinstein, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Cheryl M. Coffin

    Vydáno 2014
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  12. 12
    Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib

    Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib Autor Victor Wong, Dean C. Pavlick, Timothy J. Brennan, Roman Yelensky, John R. Crawford, Jeffrey S. Ross, Vincent A. Miller, Denise Malicki, Philip J. Stephens, Siraj M. Ali, Hyunah Ahn

    Vydáno 2015
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  13. 13
    Oncogenic Alterations in <i>ERBB2/HER2</i> Represent Potential Therapeutic Targets Across Tumors From Diverse Anatomic Sites of Origin

    Oncogenic Alterations in <i>ERBB2/HER2</i> Represent Potential Therapeutic Targets Across Tumors From Diverse Anatomic Sites of Origin Autor Juliann Chmielecki, Jeffrey S. Ross, Kai Wang, Garrett M. Frampton, Gary A. Palmer, Siraj M. Ali, Norma Alonzo Palma, Deborah Morosini, Vincent A. Miller, Roman Yelensky, Doron Lipson, Philip J. Stephens

    Vydáno 2014
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  14. 14
    Response of an <i>ERBB2</i>-Mutated Inflammatory Breast Carcinoma to Human Epidermal Growth Factor Receptor 2–Targeted Therapy

    Response of an <i>ERBB2</i>-Mutated Inflammatory Breast Carcinoma to Human Epidermal Growth Factor Receptor 2–Targeted Therapy Autor Siraj M. Ali, R. Katherine Alpaugh, Sean R. Downing, Philip J. Stephens, Jian Yu, Hong Wu, Jamie Buell, Vincent A. Miller, Doron Lipson, Gary A. Palmer, Jeffrey S. Ross, Massimo Cristofanilli

    Vydáno 2014
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  15. 15
    Genomic Profiling of Small-Bowel Adenocarcinoma

    Genomic Profiling of Small-Bowel Adenocarcinoma Autor Alexa B. Schrock, Craig Devoe, Robert R. McWilliams, James Sun, Thomas Aparicio, Philip J. Stephens, Jeffrey S. Ross, Richard H. Wilson, Vincent A. Miller, Siraj M. Ali, Michael J. Overman

    Vydáno 2017
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  16. 16
    Novel Chromosomal Rearrangements and Break Points at the t(6;9) in Salivary Adenoid Cystic Carcinoma: Association with <i>MYB</i>–<i>NFIB</i> Chimeric Fusion, <i>MYB</i> Expression, and Clinical Outcome

    Novel Chromosomal Rearrangements and Break Points at the t(6;9) in Salivary Adenoid Cystic Carcinoma: Association with <i>MYB</i>–<i>NFIB</i> Chimeric Fusion, <i>MYB</i> Expression... Autor Yoshitsugu Mitani, Pulivarthi H. Rao, P. Andrew Futreal, Dianna Roberts, Philip J. Stephens, Yi-Jue Zhao, Li Zhang, Mutsumi Mitani, Randal S. Weber, Scott M. Lippman, Carlos Caulı́n, Adel K. El‐Naggar

    Vydáno 2011
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  17. 17
    Identification and characterization of <i>RET</i> fusions in advanced colorectal cancer

    Identification and characterization of <i>RET</i> fusions in advanced colorectal cancer Autor Anne-France Le Rolle, Samuel J. Klempner, Christopher R. Garrett, Tara Elisabeth Seery, Eric M. Sanford, Sohail Balasubramanian, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Siraj M. Ali, Vi K. Chiu

    Vydáno 2015
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  18. 18
    Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer

    Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer Autor Andrew Rankin, Samuel J. Klempner, Rachel Erlich, James Sun, Axel Grothey, Marwan Fakih, Thomas J. George, Jeeyun Lee, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Siraj M. Ali, Alexa B. Schrock

    Vydáno 2016
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  19. 19
    Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway

    Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Autor Jennifer J. Wheler, Stacy Moulder, Aung Naing, Filip Janků, Sarina A. Piha‐Paul, Gerald S. Falchook, Ralph Zinner, Apostolia M. Tsimberidou, Siqing Fu, David S. Hong, Johnique T. Atkins, Roman Yelensky, Philip J. Stephens, Razelle Kurzrock

    Vydáno 2014
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  20. 20
    Next-Generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib-Sensitive ALK Rearrangement in a Patient with Metastatic Non–Small-Cell Lung Cancer

    Next-Generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib-Sensitive ALK Rearrangement in a Patient with Metastatic Non–Small-Cell Lung Cancer Autor Nir Peled, Gary A. Palmer, Fred R. Hirsch, Murry W. Wynes, Maya Ilouze, Marileila Varella‐Garcia, Lior Soussan‐Gutman, Geoff Otto, Philip J. Stephens, Jeffrey S. Ross, Maureen Cronin, Doron Lipson, Vincent A. Miller

    Vydáno 2012
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