Resultados da pesquisa - Paul T. Kirschmeier

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  1. 1
    Thematic review series: Lipid Posttranslational Modifications. Farnesyl transferase inhibitors

    Thematic review series: Lipid Posttranslational Modifications. Farnesyl transferase inhibitors Por Andrea Basso, Paul T. Kirschmeier, W. Robert Bishop

    Publicado em 2005
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  2. 2
    AKT1, AKT2 and AKT3-dependent cell survival is cell line-specific and knockdown of all three isoforms selectively induces apoptosis in 20 human tumor cell lines

    AKT1, AKT2 and AKT3-dependent cell survival is cell line-specific and knockdown of all three isoforms selectively induces apoptosis in 20 human tumor cell lines Por Sandra Koseoglu, Zhuomei Lu, C. Chandra Kumar, Paul T. Kirschmeier, Jun Zou

    Publicado em 2007
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  3. 3
    The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling

    The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling Por Andrea Basso, Asra Mirza, Gongjie Liu, Brian J. Long, W. Robert Bishop, Paul T. Kirschmeier

    Publicado em 2005
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  4. 4
    Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family.

    Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family. Por Gerard M. Housey, C A O'Brian, Mark D. Johnson, Paul T. Kirschmeier, I. Bernard Weinstein

    Publicado em 1987
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  5. 5
    Farnesyl Transferase Inhibitors Block the Farnesylation of CENP-E and CENP-F and Alter the Association of CENP-E with the Microtubules

    Farnesyl Transferase Inhibitors Block the Farnesylation of CENP-E and CENP-F and Alter the Association of CENP-E with the Microtubules Por Hena R. Ashar, Linda James, Kimberly Gray, Donna Carr, Stuart Black, Lydia Armstrong, W. Robert Bishop, Paul T. Kirschmeier

    Publicado em 2000
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  6. 6
    A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies

    A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies Por John Nemunaitis, Karen Small, Paul T. Kirschmeier, Da Zhang, Yali Zhu, Ying‐Ming Jou, Paul Statkevich, Siu‐Long Yao, Rajat Bannerji

    Publicado em 2013
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  7. 7
    Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors

    Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors Por Terrill K. McClanahan, Sandra Koseoglu, Kathleen B. Smith, Jeffrey Grein, Eric A. Gustafson, Stuart Black, Paul T. Kirschmeier, Ahmed A. Samatar

    Publicado em 2006
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  8. 8
    K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors

    K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors Por David B. Whyte, Paul T. Kirschmeier, Tish Hockenberry, Irma Nunez-Oliva, Linda James, Joseph J. Catino, W. Robert Bishop, Jin-Keon Pai

    Publicado em 1997
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  9. 9
    Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches

    Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches Por Luquan Wang, Qun Wu, Ping Qiu, Asra Mirza, Marnie McGuirk, Paul T. Kirschmeier, Jonathan Greene, Yaolin Wang, Cecil B. Pickett, Suxing Liu

    Publicado em 2001
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  10. 10
    Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia

    Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia Por David G. Peters, Russell R. Hoover, Melissa J. Gerlach, Eugene Y. Koh, Haiyan Zhang, Kevin S. Choe, Paul T. Kirschmeier, W. Robert Bishop, George Q. Daley

    Publicado em 2001
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  11. 11
    Characterization of Ha-Ras, N-Ras, Ki-Ras4A, and Ki-Ras4B as in Vitro Substrates for Farnesyl Protein Transferase and Geranylgeranyl Protein Transferase Type I

    Characterization of Ha-Ras, N-Ras, Ki-Ras4A, and Ki-Ras4B as in Vitro Substrates for Farnesyl Protein Transferase and Geranylgeranyl Protein Transferase Type I Por Fang L. Zhang, Paul T. Kirschmeier, Donna Carr, Linda James, Richard Bond, Lynn Wang, Robert Patton, William T. Windsor, Rosalinda Syto, Rumin Zhang, W. Robert Bishop

    Publicado em 1997
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  12. 12
    Rho Family GTPase Modification and Dependence on CAAX Motif-signaled Posttranslational Modification

    Rho Family GTPase Modification and Dependence on CAAX Motif-signaled Posttranslational Modification Por Patrick J. Roberts, Natalia Mitin, Patricia J. Keller, Emily J. Chenette, James P. Madigan, Rachel O. Currin, Adrienne D. Cox, Oswald Wilson, Paul T. Kirschmeier, Channing J. Der

    Publicado em 2008
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  13. 13
    Transcriptional Regulation during p21/-induced Apoptosis in Human Ovarian Cancer Cells

    Transcriptional Regulation during p21/-induced Apoptosis in Human Ovarian Cancer Cells Por Qun Wu, Paul T. Kirschmeier, Tish Hockenberry, Tong‐Yuan Yang, Diana Brassard, Luquan Wang, Terri McClanahan, Stuart Black, Giovanni Rizzi, Mary Lynn Musco, Asra Mirza, Suxing Liu

    Publicado em 2002
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  14. 14
    Noninvasive Detection of Response and Resistance in <i>EGFR</i>-Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA

    Noninvasive Detection of Response and Resistance in <i>EGFR</i>-Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA Por Geoffrey R. Oxnard, Cloud P. Paweletz, Yanan Kuang, Stacy L. Mach, Allison O’Connell, Melissa M. Messineo, Jason J. Luke, Mohit Butaney, Paul T. Kirschmeier, David M. Jackman, Pasi A. Jänne

    Publicado em 2014
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  15. 15
    Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

    Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway Por Asra Mirza, Marnie McGuirk, Tish Hockenberry, Qun Wu, Hena R. Ashar, Stuart Black, Shu Fen Wen, Luquan Wang, Paul T. Kirschmeier, W. Robert Bishop, Loretta L. Nielsen, Cecil B. Pickett, Suxing Liu

    Publicado em 2002
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  16. 16
    Novel Tricyclic Inhibitors of Farnesyl Protein Transferase

    Novel Tricyclic Inhibitors of Farnesyl Protein Transferase Por W. Robert Bishop, Richard Bond, Joanne Petrin, Lynn Wang, Robert Patton, Ronald J. Doll, George Njoroge, Joseph J. Catino, Jerome Schwartz, William T. Windsor, Rosalinda Syto, Jeffrey H. Schwartz, Donna Carr, Linda James, Paul T. Kirschmeier

    Publicado em 1995
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  17. 17
    Bias-Corrected Targeted Next-Generation Sequencing for Rapid, Multiplexed Detection of Actionable Alterations in Cell-Free DNA from Advanced Lung Cancer Patients

    Bias-Corrected Targeted Next-Generation Sequencing for Rapid, Multiplexed Detection of Actionable Alterations in Cell-Free DNA from Advanced Lung Cancer Patients Por Cloud P. Paweletz, Adrian G. Sacher, Chris K. Raymond, Ryan S. Alden, Allison O’Connell, Stacy L. Mach, Yanan Kuang, Leena Gandhi, Paul T. Kirschmeier, Jessie M. English, Lee P. Lim, Pasi A. Jänne, Geoffrey R. Oxnard

    Publicado em 2015
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  18. 18
    Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity

    Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity Por Juan J. Miret, Paul T. Kirschmeier, Shohei Koyama, Mingrui Zhu, Yvonne Y. Li, Yujiro Naito, Min Wu, Venkat S. Malladi, Wei Huang, William H. Walker, Sangeetha Palakurthi, Glenn Dranoff, Peter S. Hammerman, Chad V. Pecot, Kwok‐Kin Wong, Esra A. Akbay

    Publicado em 2019
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  19. 19
    Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer

    Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer Por Shunsuke Kitajima, Elena Ivanova, Sujuan Guo, Ryohei Yoshida, Marco Campisi, Shriram K. Sundararaman, Shoichiro Tange, Yoichiro Mitsuishi, Tran C. Thai, Sayuri Masuda, Brandon Piel, Lynette M. Sholl, Paul T. Kirschmeier, Cloud P. Paweletz, Hideo Watanabe, Mamiko Yajima, David A. Barbie

    Publicado em 2018
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  20. 20
    Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor

    Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor Por David Parry, Timothy J. Guzi, Fergus Shanahan, Nicole R. Davis, Deepa Prabhavalkar, Derek Wiswell, Wolfgang Seghezzi, Kamil Paruch, Michael P. Dwyer, Ronald J. Doll, Amin A. Nomeir, William T. Windsor, Thierry Fischmann, Yaolin Wang, Martin Oft, Taiying Chen, Paul T. Kirschmeier, Emma Lees

    Publicado em 2010
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