檢索結果 - Pascal Furet

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  1. 1
    Modulation of the SH2 Binding Specificity and Kinase Activity of Src by Tyrosine Phosphorylation within Its SH2 Domain

    Modulation of the SH2 Binding Specificity and Kinase Activity of Src by Tyrosine Phosphorylation within Its SH2 Domain 由 David R. Stover, Pascal Furet, Nicholas Lydon

    出版 1996
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  2. 2
    Analysis of the Structural Basis of Specificity of Inhibition of the Abl Kinase by STI571

    Analysis of the Structural Basis of Specificity of Inhibition of the Abl Kinase by STI571 由 Amie S. Corbin, Elisabeth Buchdunger, Pascal Furet, Brian J. Druker

    出版 2002
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  3. 3
    Prediction of Resistance to Small Molecule FLT3 Inhibitors

    Prediction of Resistance to Small Molecule FLT3 Inhibitors 由 Jan Cools, Nicole Mentens, Pascal Furet, Doriano Fabbro, Jennifer Clark, James D. Griffin, Peter Marynen, D. Gary Gilliland

    出版 2004
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  4. 4
    Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue

    Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue 由 Patrick Chêne, Joëlle Rudloff, Joseph Schoepfer, Pascal Furet, Peter Meier, Zhiyan Qian, Jean‐Marc Schlaeppi, Rita Schmitz, Thomas Radimerski

    出版 2009
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  5. 5
    Selective In Vivo and In Vitro Effects of a Small Molecule Inhibitor of Cyclin-Dependent Kinase 4

    Selective In Vivo and In Vitro Effects of a Small Molecule Inhibitor of Cyclin-Dependent Kinase 4 由 Rajeev Soni, T. O'Reilly, Pascal Furet, L Müller, Christine Stephan, Sabine Zumstein-Mecker, Heinz Fretz, Doriano Fabbro, Bhabatosh Chaudhuri

    出版 2001
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  6. 6
    Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes

    Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes 由 Joerg Kallen, A. Goepfert, Anke Blechschmidt, Aude Izaac, Martin Geiser, Gisele Tavares, Paul Ramage, Pascal Furet, Keiichi Masuya, Joanna Lisztwan

    出版 2009
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  7. 7
    The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis

    The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis 由 Georg Martiny‐Baron, Philipp Holzer, Éric Billy, Christian Schnell, Joseph Brueggen, Mireille Ferretti, Niko Schmiedeberg, Jeanette M. Wood, Pascal Furet, Patricia Imbach

    出版 2010
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  8. 8
    2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4

    2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4 由 Thomas Knoepfel, Pascal Furet, Robert Mah, Nicole Buschmann, Catherine Leblanc, Sebastien Ripoche, Diana Graus-Porta, Markus Wartmann, Inga Galuba, Robin A. Fairhurst

    出版 2018
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  9. 9
    Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia

    Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia 由 Sandra W. Cowan‐Jacob, Gabriele Fendrich, Andreas Floersheimer, Pascal Furet, Janis Liebetanz, Gabriele Rummel, Paul Rheinberger, Mario Centeleghe, Doriano Fabbro, Paul W. Manley

    出版 2006
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  10. 10
    Different Susceptibility of Protein Kinases to Staurosporine Inhibition

    Different Susceptibility of Protein Kinases to Staurosporine Inhibition 由 Flavio Meggio, Arianna Donella Deana, Maria Ruzzene, Anna Maria Brunati, Luca Cesaro, Bárbara Guerra, Thomas Meyer, Helmut Mett, Doriano Fabbro, Pascal Furet, Grażyna Dobrowolska, Lorenzo A. Pinna

    出版 1995
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  11. 11
    p53 dynamics vary between tissues and are linked with radiation sensitivity

    p53 dynamics vary between tissues and are linked with radiation sensitivity 由 Jacob Stewart-Ornstein, Yoshiko Iwamoto, Miles A. Miller, Mark Prytyskach, Stéphane Ferretti, Philipp Holzer, Joerg Kallen, Pascal Furet, Ashwini Jambhekar, William C. Forrester, Ralph Weissleder, Galit Lahav

    出版 2021
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  12. 12
    Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)

    Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA) 由 Stefania Sarno, E. De Moliner, Maria Ruzzene, Mario A. Pagano, Roberto Battistutta, Jenny Bain, Doriano Fabbro, Joseph Schoepfer, Matthew Elliott, Pascal Furet, Flavio Meggio, Giuseppe Zanotti, Lorenzo A. Pinna

    出版 2003
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  13. 13
    Capmatinib (INC280) Is Active Against Models of Non–Small Cell Lung Cancer and Other Cancer Types with Defined Mechanisms of MET Activation

    Capmatinib (INC280) Is Active Against Models of Non–Small Cell Lung Cancer and Other Cancer Types with Defined Mechanisms of MET Activation 由 Sabrina Baltschukat, Barbara Schacher Engstler, Alan Huang, Huai-Xiang Hao, Angela Tam, Hui Qin Wang, Jinsheng Liang, Matthew T. DiMare, Hyo-Eun Carrie Bhang, Youzhen Wang, Pascal Furet, William R. Sellers, Francesco Hofmann, Joseph Schoepfer, Ralph Tiedt

    出版 2019
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  14. 14
    Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy <i>in Vivo</i>

    Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy <i>in Vivo</i> 由 Ayako Honda, Edmund Harrington, Iván Cornella‐Taracido, Pascal Furet, Mark Knapp, Meir Glick, Ellen Triantafellow, William E. Dowdle, Dmitri Wiedershain, Wieslawa Maniara, Christine Moore, Peter M. Finan, Lawrence G. Hamann, Brant Firestone, Leon O. Murphy, Erin P. Keaney

    出版 2015
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  15. 15
    In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

    In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase 由 Carlos Garcı́a-Echeverrı́a, Mark Pearson, Andreas Marti, Thomas Meyer, Juergen Mestan, Johann Zimmermann, Jiaping Gao, Josef Brueggen, Hans‐Georg Capraro, Robert Cozens, Dean B. Evans, Doriano Fabbro, Pascal Furet, Diana Graus Porta, Janis Liebetanz, Georg Martiny‐Baron, Stephan Ruetz, Francesco Hofmann

    出版 2004
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  16. 16
    A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients

    A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients 由 Ralph Tiedt, Elisa Degenkolbe, Pascal Furet, B.A. Appleton, Sabrina Wagner, Joseph Schoepfer, Emily Buck, David A. Ruddy, John E. Monahan, Michael D. Jones, Jutta Blank, Dorothea Haasen, Peter Drueckes, Markus Wartmann, Clive McCarthy, William R. Sellers, Francesco Hofmann

    出版 2011
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  17. 17
    Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent <i>in vivo</i> antitumor activity

    Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent <i>in vivo</i> anti... 由 Sauveur-Michel Maira, Frédéric Stauffer, Josef Brueggen, Pascal Furet, Christian Schnell, Christine Fritsch, Saskia M. Brachmann, Patrick Chêne, Alain De Pover, Kevin Schoemaker, Doriano Fabbro, Daniela Gabriel, Marjo Simonen, Leon O. Murphy, Peter M. Finan, William R. Sellers, Carlos García-Echeverría

    出版 2008
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  18. 18
    Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

    Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805 由 Fabienne Baffert, Catherine H. Régnier, Alain De Pover, Carole Pissot‐Soldermann, Gisele Tavares, Francesca Blasco, Josef Brueggen, Patrick Chêne, Peter Drueckes, Dirk Erdmann, Pascal Furet, Marc Gerspacher, Marc Lang, David Ledieu, Lynda Nolan, Stephan Ruetz, Joerg Trappe, Eric Vangrevelinghe, Markus Wartmann, Lorenza Wyder, Francesco Hofmann, Thomas Radimerski

    出版 2010
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  19. 19
    A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097

    A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097 由 Sébastien Jeay, Swann Gaulis, Stéphane Ferretti, Hans Bitter, Moriko Ito, Therese‐Marie Stachyra, Masato Murakami, Stephan Ruetz, Daniel Guthy, Caroline Rynn, Michael Rugaard Jensen, Marion Wiesmann, Joerg Kallen, Pascal Furet, F. Gessier, Philipp Holzer, Keiichi Masuya, Jens Würthner, Ensar Halilovic, Francesco Hofmann, William R. Sellers, Diana Graus Porta

    出版 2015
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  20. 20
    FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer

    FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer 由 Andreas Weiss, Flavia Adler, Alexandra Buhles, Christelle Stamm, Robin A. Fairhurst, Michael Kiffe, Dario Sterker, Mario Centeleghe, Markus Wartmann, Jacqueline Kinyamu-Akunda, Heiko S. Schadt, Philippe Couttet, Wolf Armin, Youzhen Wang, Patrizia Barzaghi-Rinaudo, Masato Murakami, Audrey Kauffmann, Thomas Knoepfel, Nicole Buschmann, Catherine Leblanc, Robert Mah, Pascal Furet, Jutta Blank, Francesco Hofmann, William R. Sellers, Diana Graus Porta

    出版 2019
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