Ohcanbohtosat - P. Filippakopoulos

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  1. 1
    The bromodomain interaction module

    The bromodomain interaction module Dahkki P. Filippakopoulos, Stefan Knapp

    Almmustuhtton 2012
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  2. 2
    Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

    Functions of bromodomain-containing proteins and their roles in homeostasis and cancer Dahkki Takao Fujisawa, P. Filippakopoulos

    Almmustuhtton 2017
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  3. 3
    Bromodomains as therapeutic targets

    Bromodomains as therapeutic targets Dahkki Susanne Müller, P. Filippakopoulos, Stefan Knapp

    Almmustuhtton 2011
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  4. 4
    SH2 domains: modulators of nonreceptor tyrosine kinase activity

    SH2 domains: modulators of nonreceptor tyrosine kinase activity Dahkki P. Filippakopoulos, Susanne Müller, Stefan Knapp

    Almmustuhtton 2009
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  5. 5
    Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

    Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family Dahkki P. Filippakopoulos, S. Picaud, O. Fedorov, Marco Keller, Matthias Wrobel, Olaf Morgenstern, Franz Bracher, Stefan Knapp

    Almmustuhtton 2011
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  6. 6
    BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy

    BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy Dahkki Marco Segatto, Roberta Szokoll, Raffaella Fittipaldi, Cinzia Bottino, Lorenzo Nevi, Kamel Mamchaoui, P. Filippakopoulos, Giuseppina Caretti

    Almmustuhtton 2020
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  7. 7
    9<i>H</i>-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain

    9<i>H</i>-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain Dahkki S. Picaud, Maria Strocchia, Stefania Terracciano, Gianluigi Lauro, Jacqui Méndez, Danette L. Daniels, Raffaele Riccio, Giuseppe Bifulco, Ines Bruno, P. Filippakopoulos

    Almmustuhtton 2015
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  8. 8
    Structure and functional characterization of the atypical human kinase haspin

    Structure and functional characterization of the atypical human kinase haspin Dahkki Jeyanthy Eswaran, Debasis Patnaik, P. Filippakopoulos, Fangwei Wang, Ross L. Stein, James W. Murray, Jonathan M.G. Higgins, Stefan Knapp

    Almmustuhtton 2009
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  9. 9
    Structural Analysis Identifies Imidazo[1,2-<i>b</i>]Pyridazines as PIM Kinase Inhibitors with <i>In vitro</i> Antileukemic Activity

    Structural Analysis Identifies Imidazo[1,2-<i>b</i>]Pyridazines as PIM Kinase Inhibitors with <i>In vitro</i> Antileukemic Activity Dahkki Vanda Pogac̆ić, Alex N. Bullock, O. Fedorov, P. Filippakopoulos, Christelle Gasser, Andrea Biondi, Sandrine Meyer‐Monard, Stefan Knapp, Juerg Schwaller

    Almmustuhtton 2007
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  10. 10
    Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening

    Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening Dahkki Lewis R. Vidler, P. Filippakopoulos, O. Fedorov, S. Picaud, Sarah Martin, Michael Tomsett, Hannah L. Woodward, Nathan Brown, Stefan Knapp, Swen Hoelder

    Almmustuhtton 2013
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  11. 11
    Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

    Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC Dahkki C. Tallant, Erica Valentini, O. Fedorov, Lois M. Overvoorde, Fleur M. Ferguson, P. Filippakopoulos, Dmitri I. Svergun, Stefan Knapp, Alessio Ciulli

    Almmustuhtton 2014
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  12. 12
    Evaluation of linker length effects on a BET bromodomain probe

    Evaluation of linker length effects on a BET bromodomain probe Dahkki Rui Traquete, Elizabeth Henderson, S. Picaud, Pedro M. S. D. Cal, Florian Sieglitz, Tiago Rodrigues, Rudi Oliveira, P. Filippakopoulos, Gonçalo J. L. Bernardes

    Almmustuhtton 2019
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  13. 13
    Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs

    Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs Dahkki Jeyanthy Eswaran, Wen‐Hwa Lee, J.E. Debreczeni, P. Filippakopoulos, Andrew V. Turnbull, O. Fedorov, Sean Deacon, Jeffrey R. Peterson, Stefan Knapp

    Almmustuhtton 2007
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  14. 14
    7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes

    7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes Dahkki K. Huber, Laurent Brault, O. Fedorov, Christelle Gasser, P. Filippakopoulos, Alex N. Bullock, Doriano Fabbro, Jörg Trappe, Jürg Schwaller, Stefan Knapp, Franz Bracher

    Almmustuhtton 2011
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  15. 15
    The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity

    The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity Dahkki C. Johansson, A.K. Roos, Sergio Montaño, Rajib Sengupta, P. Filippakopoulos, Kunde Guo, F. von Delft, Arne Holmgren, Udo Oppermann, K.L. Kavanagh

    Almmustuhtton 2010
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  16. 16
    Structural and Functional Characterization of the Human Protein Kinase ASK1

    Structural and Functional Characterization of the Human Protein Kinase ASK1 Dahkki G. Bunkóczi, E. Salah, P. Filippakopoulos, O. Fedorov, Susanne Müller, Frank Sobott, Sirlester A. Parker, Haifeng Zhang, Min Wang, Benjamin E. Turk, Stefan Knapp

    Almmustuhtton 2007
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  17. 17
    Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

    Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome Dahkki A. Barr, E. Ugochukwu, Wen‐Hwa Lee, Oliver N. F. King, P. Filippakopoulos, I. Alfano, P. Savitsky, N. Burgess-Brown, Susanne Müller, Stefan Knapp

    Almmustuhtton 2009
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  18. 18
    Structural Basis for Par-4 Recognition by the SPRY Domain- and SOCS Box-Containing Proteins SPSB1, SPSB2, and SPSB4

    Structural Basis for Par-4 Recognition by the SPRY Domain- and SOCS Box-Containing Proteins SPSB1, SPSB2, and SPSB4 Dahkki P. Filippakopoulos, Andrew Low, Timothy Sharpe, J. Uppenberg, Shenggen Yao, Zhihe Kuang, P. Savitsky, Rowena S. Lewis, Sandra E. Nicholson, Raymond S. Norton, Alex N. Bullock

    Almmustuhtton 2010
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  19. 19
    Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition

    Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition Dahkki M. Soundararajan, A.K. Roos, P. Savitsky, P. Filippakopoulos, Arminja N. Kettenbach, Jesper V. Olsen, Scott A. Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M. Elkins

    Almmustuhtton 2013
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  20. 20
    MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway

    MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway Dahkki Amber L. Couzens, Shawn Xiong, James D.R. Knight, Daniel Y.L. Mao, Sebastian Guettler, S. Picaud, Igor Kurinov, P. Filippakopoulos, Frank Sicheri, Anne‐Claude Gingras

    Almmustuhtton 2017
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