Resultats de la cerca - Nicholas D. Adams

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  1. 1
    Reductive carboxylation supports redox homeostasis during anchorage-independent growth

    Reductive carboxylation supports redox homeostasis during anchorage-independent growth per Lei Jiang, Alexander A. Shestov, Pamela Swain, Chendong Yang, Seth J. Parker, Qiong Wang, Lance S. Terada, Nicholas D. Adams, Michael T. McCabe, Beth Pietrak, Stan Schmidt, Christian M. Metallo, Brian P. Dranka, Benjamin Schwartz, Ralph J. DeBerardinis

    Publicat 2016
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  2. 2
    Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)

    Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT) per Hongfang Yang, Patrícia Flores de Medeiros, Kaushik Raha, P.A. Elkins, Kenneth Lind, Ruth Lehr, Nicholas D. Adams, Joelle L. Burgess, Stanley J. Schmidt, Steven D. Knight, Kurt R. Auger, Michael D. Schaber, G. Joseph Franklin, Yun Ding, Jennifer L. DeLorey, Paolo A. Centrella, Sibongile Mataruse, Steven R. Skinner, Matthew Clark, John W. Cuozzo, Ghotas Evindar

    Publicat 2015
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  3. 3
    Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

    Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin per Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess, Amita M. Chaudhari, Michael G. Darcy, Carla A. Donatelli, Juan I. Luengo, K. A. NEWLANDER, Cynthia A. Parrish, Lance H. Ridgers, Martha A. Sarpong, Stanley J. Schmidt, Glenn S. Van Aller, Jeffrey D. Carson, Melody Diamond, P.A. Elkins, Christine Gardiner, Eric Garver, S. Gilbert, Richard R. Gontarek, Jeffrey R. Jackson, Kevin L. Kershner, Lusong Luo, Kaushik Raha, Christian Sherk, Chiu-Mei Sung, David Sutton, Peter J. Tummino, Ronald Wegrzyn, Kurt R. Auger, Dashyant Dhanak

    Publicat 2010
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  4. 4
    New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

    New IDH1 mutant inhibitors for treatment of acute myeloid leukemia per Ujunwa Cynthia Okoye-Okafor, Boris Bartholdy, Jessy Cartier, Enoch Gao, Beth Pietrak, Alan R. Rendina, Cynthia M. Rominger, Chad Quinn, Angela Smallwood, Kenneth J. Wiggall, Alexander Reif, Stanley J. Schmidt, Hongwei Qi, Huizhen Zhao, Gérard Joberty, Maria Faelth-Savitski, Marcus Bantscheff, Gerard Drewes, Chaya Duraiswami, Pat Brady, Arthur Groy, Swathi-Rao Narayanagari, Iléana Antony‐Debré, Kelly Mitchell, Heng Rui Wang, Yun-Ruei Kao, Maximilian Christopeit, Luis A. Carvajal, Laura Barreyro, Elisabeth Paietta, Hideki Makishima, Britta Will, N.O. Concha, Nicholas D. Adams, Benjamin Schwartz, Michael T. McCabe, J. Maciejewski, Amit Verma, Ulrich Steidl

    Publicat 2015
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  5. 5
    Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295

    Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295 per Xiangping Qian, Andrew McDonald, Han-Jie Zhou, Nicholas D. Adams, Cynthia A. Parrish, Kevin J. Duffy, Duke M. Fitch, Rosanna Tedesco, Luke Ashcraft, Bing Yao, Hong Jiang, Jennifer Huang, Melchor V. Marin, Carrie E. Aroyan, Jianchao Wang, Seyed Ahmed, Joelle L. Burgess, Amita M. Chaudhari, Carla A. Donatelli, Michael G. Darcy, Lance H. Ridgers, K. A. NEWLANDER, Stanley J. Schmidt, Deping Chai, Mariela Colón, Michael N. Zimmerman, Latesh Lad, Roman Sakowicz, Stephen E. Schauer, Lisa D. Belmont, Ramesh Baliga, Daniel W. Pierce, Jeffrey T. Finer, Zhengping Wang, B. Paul Morgan, David J. Morgans, Kurt R. Auger, Chiu-Mei Sung, Jeff D. Carson, Lusong Luo, Erin Hugger, Robert A. Copeland, David Sutton, John D. Elliott, Jeffrey R. Jackson, Kenneth W. Wood, Dashyant Dhanak, Gustave Bergnes, Steven D. Knight

    Publicat 2010
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  6. 6
    Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss

    Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss per Andrew Fedoriw, Satyajit Rajapurkar, Shane W. O’Brien, Sarah V. Gerhart, Lorna H. Mitchell, Nicholas D. Adams, Nathalie Rioux, Trupti Lingaraj, Scott Ribich, Melissa B. Pappalardi, Niyant Shah, Jenny Laraio, Yan Liu, Michael Butticello, Chris Carpenter, Caretha L. Creasy, Susan Korenchuk, Michael T. McCabe, Charles F. McHugh, Raman P. Nagarajan, Craig D. Wagner, Francesca Zappacosta, Roland S. Annan, N.O. Concha, Roberta Thomas, Timothy K. Hart, J. Joshua Smith, Robert A. Copeland, Mikel P. Moyer, John Campbell, Kim Stickland, James E. Mills, Suzanne Jacques-O’Hagan, Christina J. Allain, Danielle Johnston, Alejandra Raimondi, Margaret Porter Scott, Nigel J. Waters, Kerren K. Swinger, Ann Boriack-Sjodin, Thomas V. Riera, Gideon Shapiro, Richard Chesworth, Rabinder Prinjha, Ryan G. Kruger, Olena Barbash, Helai P. Mohammad

    Publicat 2019
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