Search Results - Nga Bien‐Ly

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  1. 1
    Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice

    Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice by Nga Bien‐Ly, Anna K. Gillespie, David Walker, Seo Yeon Yoon, Yadong Huang

    Published 2012
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  2. 2
    C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid-β (Aβ) and acts in concert with Aβ to elicit neuronal and behavioral deficits in mice

    C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid-β (Aβ) and acts in concert with Aβ to elicit neuronal and behavioral deficits in mice by Nga Bien‐Ly, Yaisa Andrews‐Zwilling, Qin Xu, Aubrey Bernardo, Charles Wang, Yadong Huang

    Published 2011
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  3. 3
    Vulnerability of Dentate Granule Cells to Disruption of Arc Expression in Human Amyloid Precursor Protein Transgenic Mice

    Vulnerability of Dentate Granule Cells to Disruption of Arc Expression in Human Amyloid Precursor Protein Transgenic Mice by Jorge J. Palop, Jeannie Chin, Nga Bien‐Ly, Catherine Massaro, Bertrand Z. Yeung, Gui-Qiu Yu, Lennart Mucke

    Published 2005
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  4. 4
    Reelin Depletion in the Entorhinal Cortex of Human Amyloid Precursor Protein Transgenic Mice and Humans with Alzheimer's Disease

    Reelin Depletion in the Entorhinal Cortex of Human Amyloid Precursor Protein Transgenic Mice and Humans with Alzheimer's Disease by Jeannie Chin, Catherine Massaro, Jorge J. Palop, Myo T. Thwin, Gui-Qiu Yu, Nga Bien‐Ly, Aaron M. Bender, Lennart Mucke

    Published 2007
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  5. 5
    Apolipoprotein E4 Produced in GABAergic Interneurons Causes Learning and Memory Deficits in Mice

    Apolipoprotein E4 Produced in GABAergic Interneurons Causes Learning and Memory Deficits in Mice by Johanna Knöferle, Seo Yeon Yoon, David Walker, Laura Leung, Anna K. Gillespie, Leslie M. Tong, Nga Bien‐Ly, Yadong Huang

    Published 2014
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  6. 6
    Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease

    Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease by Jeannie Chin, Jorge J. Palop, Jukka Puoliväli, Catherine Massaro, Nga Bien‐Ly, Hertzel C. Gerstein, Kimberly Scearce‐Levie, Eliezer Masliah, Lennart Mucke

    Published 2005
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  7. 7
    GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice

    GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice by Gang Li, Nga Bien‐Ly, Yaisa Andrews‐Zwilling, Qin Xu, Aubrey Bernardo, Karen Ring, Brian Halabisky, Changhui Deng, Robert W. Mahley, Yadong Huang

    Published 2009
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  8. 8
    Reduction in Mitochondrial Superoxide Dismutase Modulates Alzheimer's Disease-Like Pathology and Accelerates the Onset of Behavioral Changes in Human Amyloid Precursor Protein Transgenic Mice

    Reduction in Mitochondrial Superoxide Dismutase Modulates Alzheimer's Disease-Like Pathology and Accelerates the Onset of Behavioral Changes in Human Amyloid Precursor Protein Tran... by Luke Esposito, Jacob Raber, Lisa Kekonius, Fengrong Yan, Giu-Qiu Yu, Nga Bien‐Ly, Jukka Puoliväli, Kimberly Scearce‐Levie, Eliezer Masliah, Lennart Mucke

    Published 2006
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  9. 9
    Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice

    Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice by Yaisa Andrews‐Zwilling, Nga Bien‐Ly, Qin Xu, Gang Li, Aubrey Bernardo, Seo Yeon Yoon, Daniel Zwilling, Tonya Xue Yan, Ligong Chen, Yadong Huang

    Published 2010
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  10. 10
    Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants

    Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants by Nga Bien‐Ly, Yang Yu, Daniela Bumbaca, Justin Elstrott, C. Andrew Boswell, Yin Zhang, Wilman Luk, Yanmei Lu, Mark S. Dennis, Robby M. Weimer, Inhee Chung, Ryan J. Watts

    Published 2014
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  11. 11
    Accelerating Amyloid-β Fibrillization Reduces Oligomer Levels and Functional Deficits in Alzheimer Disease Mouse Models

    Accelerating Amyloid-β Fibrillization Reduces Oligomer Levels and Functional Deficits in Alzheimer Disease Mouse Models by Irene H. Cheng, Kimberly Scearce‐Levie, Justin Legleiter, Jorge J. Palop, Hertzel C. Gerstein, Nga Bien‐Ly, Jukka Puoliväli, Sylvain Lesné, Karen H. Ashe, Paul J. Muchowski, Lennart Mucke

    Published 2007
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  12. 12
    Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies

    Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies by Nga Bien‐Ly, C. Andrew Boswell, Surinder Jeet, Thomas G. Beach, Kwame Hoyte, Wilman Luk, Vera Shihadeh, Sheila Ulufatu, Oded Foreman, Yanmei Lu, Jason DeVoss, Marcel van der Brug, Ryan J. Watts

    Published 2015
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  13. 13
    Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease

    Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease by Jorge J. Palop, Jeannie Chin, Erik D. Roberson, Jun Wang, Myo T. Thwin, Nga Bien‐Ly, Jong W. Yoo, Kaitlyn O. Ho, Gui-Qiu Yu, Anatol C. Kreitzer, Steven Finkbeiner, Jeffrey L. Noebels, Lennart Mucke

    Published 2007
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  14. 14
    Hilar GABAergic Interneuron Activity Controls Spatial Learning and Memory Retrieval

    Hilar GABAergic Interneuron Activity Controls Spatial Learning and Memory Retrieval by Yaisa Andrews‐Zwilling, Anna K. Gillespie, Alexxai V. Kravitz, Alexandra Nelson, Nino Devidze, Iris Lo, Seo Yeon Yoon, Nga Bien‐Ly, Karen Ring, Daniel Zwilling, Gregory B. Potter, John L.R. Rubenstein, Anatol C. Kreitzer, Yadong Huang

    Published 2012
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  15. 15
    APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function

    APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function by Monica Xiong, Hong Jiang, Javier Remolina Serrano, Ernesto R. Gonzales, Chao Wang, Maud Gratuze, Rosa Hoyle, Nga Bien‐Ly, Adam P. Silverman, Patrick M. Sullivan, Ryan J. Watts, Jason D. Ulrich, Gregory J. Zipfel, David M. Holtzman

    Published 2021
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  16. 16
    Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies

    Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies by Y. Joy Yu Zuchero, Xiaocheng Chen, Nga Bien‐Ly, Daniela Bumbaca, Raymond K. Tong, Xiaoying Gao, Shuo Zhang, Kwame Hoyte, Wilman Luk, Melanie A. Huntley, Lilian Phu, Christine Tan, Dara Kallop, Robby M. Weimer, Yanmei Lu, Donald S. Kirkpatrick, James A. Ernst, Ben Chih, Mark S. Dennis, Ryan J. Watts

    Published 2015
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  17. 17
    Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

    Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist by Alexandra Litvinchuk, Jung H. Suh, Jing Guo, Karin Lin, Sonnet S. Davis, Nga Bien‐Ly, Eric Tycksen, G. Travis Tabor, Javier Remolina Serrano, Melissa Manis, Xin Bao, Choonghee Lee, Megan E. Bosch, Enmanuel J. Perez, Carla M. Yuede, Anil G. Cashikar, Jason D. Ulrich, Gilbert Di Paolo, David M. Holtzman

    Published 2023
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  18. 18
    Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

    Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist by Alexandra Litvinchuk, Jung H. Suh, Jing Guo, Karin Lin, Sonnet S. Davis, Nga Bien‐Ly, Eric Tycksen, G. Travis Tabor, Javier Remolina Serrano, Melissa Manis, Xin Bao, Choonghee Lee, Megan E. Bosch, Enmanuel J. Perez, Carla M. Yuede, Anil G. Cashikar, Jason D. Ulrich, Gilbert Di Paolo, David M. Holtzman

    Published 2024
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  19. 19
    Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation

    Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation by Fan Liao, Aimin Li, Monica Xiong, Nga Bien‐Ly, Hong Jiang, Yin Zhang, Mary Beth Finn, Rosa Hoyle, Jennifer Keyser, Katheryn B. Lefton, Grace O. Robinson, Javier Remolina Serrano, Adam P. Silverman, Jing Guo, Jennifer A. Getz, Kirk R. Henne, Cheryl E. G. Leyns, Gilbert Gallardo, Jason D. Ulrich, Patrick M. Sullivan, Paul Lerner, Eloïse Hudry, Zachary K. Sweeney, Mark S. Dennis, Bradley T. Hyman, Ryan J. Watts, David M. Holtzman

    Published 2018
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