نتائج البحث - Nathaniel D. Catron
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Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-X<sub>L</sub> Inhibitor حسب Le Wang, George Doherty, Andrew S. Judd, Zhi‐Fu Tao, Terkel Hansen, Robin R. Frey, Xiaohong Song, Milan Bruncko, Aaron Kunzer, Xilu Wang, Michael Wendt, John A. Flygare, Nathaniel D. Catron, Russell A. Judge, Chang H. Park, Shashank Shekhar, Darren C. Phillips, Paul Nimmer, Morey L. Smith, Stephen K. Tahir, Xiao Yu, John Xue, Haichao Zhang, Phuong N Le, Michael J. Mitten, Erwin R. Boghaert, Wenqing Gao, Peter Kovar, Edna F. Choo, Dolores Diaz, Wayne J. Fairbrother, Steven W. Elmore, Deepak Sampath, Joel D. Leverson, Andrew J. Souers
منشور في 2020Artigo -
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Discovery of a Potent and Selective BCL-X<sub>L</sub> Inhibitor with <i>in Vivo</i> Activity حسب Zhi‐Fu Tao, Lisa Hasvold, Le Wang, Xilu Wang, Andrew M. Petros, Chang H. Park, Erwin R. Boghaert, Nathaniel D. Catron, Jun Chen, Peter M. Colman, Peter E. Czabotar, Kurt Deshayes, Wayne J. Fairbrother, John A. Flygare, S.G. Hymowitz, Sha Jin, Russell A. Judge, Michael F. T. Koehler, Peter Kovar, Guillaume Lessène, Michael J. Mitten, Chudi Ndubaku, Paul Nimmer, Hans E. Purkey, Anatol Oleksijew, Darren C. Phillips, Brad E. Sleebs, Brian J. Smith, Morey L. Smith, Stephen K. Tahir, Keith G. Watson, Xiao Yu, John Xue, Haichao Zhang, Kerry Zobel, Saul H. Rosenberg, Chris Tse, Joel D. Leverson, Steven W. Elmore, Andrew J. Souers
منشور في 2014Artigo
أدوات البحث:
موضوعات ذات صلة
Biochemistry
Chemistry
Biology
Computational biology
In vitro
Pharmacology
Small molecule
Stereochemistry
Apoptosis
Cancer research
Cell culture
Chromatography
Computer science
Computer security
Drug
Drug discovery
Genetics
In vivo
Inhibitor of apoptosis
Key (lock)
Lead compound
Medicine
Membrane
Orally active
Organic chemistry
Pharmacophore
Programmed cell death
Supersaturation
Virtual screening