检索结果 - Morvarid Mohseni

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  1. 1
    Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer

    Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer 由 Masaki Mori, Robinson Triboulet, Morvarid Mohseni, Karin Schlegelmilch, Kriti Shrestha, Fernando D. Camargo, Richard I. Gregory

    出版 2014
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  2. 2
    Dematin and Adducin Provide a Novel Link between the Spectrin Cytoskeleton and Human Erythrocyte Membrane by Directly Interacting with Glucose Transporter-1

    Dematin and Adducin Provide a Novel Link between the Spectrin Cytoskeleton and Human Erythrocyte Membrane by Directly Interacting with Glucose Transporter-1 由 Anwar Khan, Toshihiko Hanada, Morvarid Mohseni, Jong‐Jin Jeong, Lixiao Zeng, Massimiliano Gaetani, Donghai Li, Brent C. Reed, David W. Speicher, Athar H. Chishti

    出版 2008
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  3. 3
    Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation

    Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation 由 Karin Schlegelmilch, Morvarid Mohseni, Oktay Kirak, Jan Pruszak, J. Renato Rodriguez, Dawang Zhou, Bridget Kreger, Valeri Vasioukhin, Joseph Avruch, Thijn R. Brummelkamp, Fernando D. Camargo

    出版 2011
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  4. 4
    Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition

    Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition 由 Jonathan R. LaRochelle, Michelle Fodor, Vidyasiri Vemulapalli, Morvarid Mohseni, Ping Wang, Travis Stams, Matthew J. LaMarche, Rajiv Chopra, Michael Acker, Stephen C. Blacklow

    出版 2018
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  5. 5
    Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR

    Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR 由 Hengyu Lu, Chen Liu, Hung Huynh, Thi Bich Uyen Le, Matthew J. LaMarche, Morvarid Mohseni, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Huai‐Xiang Hao

    出版 2020
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  6. 6
    Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2

    Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2 由 Jonathan R. LaRochelle, Michelle Fodor, Jana M. Ellegast, Xiaoxi Liu, Vidyasiri Vemulapalli, Morvarid Mohseni, Travis Stams, Sara J. Buhrlage, Kimberly Stegmaier, Matthew J. LaMarche, Michael Acker, Stephen C. Blacklow

    出版 2017
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  7. 7
    A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

    A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway 由 Morvarid Mohseni, Jianlong Sun, Allison N. Lau, Stephen J. Curtis, Jeffrey D. Goldsmith, Victor L. Fox, Chongjuan Wei, Marsha L. Frazier, Owen Samson, Kwok‐Kin Wong, Carla F. Kim, Fernando D. Camargo

    出版 2013
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  8. 8
    Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis

    Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis 由 Zhigang Cai, Jonathan J. Kotzin, Baskar Ramdas, Sisi Chen, Sai Nelanuthala, Lakshmi Reddy Palam, Ruchi Pandey, Raghuveer Singh Mali, Yan Liu, Mark R. Kelley, George E. Sandusky, Morvarid Mohseni, Adam Williams, Jorge Henao-Mejía, Reuben Kapur

    出版 2018
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  9. 9
    SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors

    SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors 由 Hengyu Lu, Chen Liu, Roberto Velazquez, Hongyun Wang, Lukas Manuel Dunkl, Malika Kazic-Legueux, Anne Haberkorn, Éric Billy, Eusebio Manchado, Saskia M. Brachmann, Susan E. Moody, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Morvarid Mohseni, Huai‐Xiang Hao

    出版 2019
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  10. 10
    Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis

    Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis 由 Allison N. Lau, Stephen J. Curtis, Christine M. Fillmore, Samuel P. Rowbotham, Morvarid Mohseni, Darcy E. Wagner, Alexander M. Beede, Daniel T. Montoro, Kerstin W. Sinkevicius, Zandra E. Walton, J.A. Morales Barrios, Daniel J. Weiss, Fernando D. Camargo, Kwok‐Kin Wong, Catherine Kim

    出版 2014
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  11. 11
    Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling

    Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling 由 Chen Liu, Hengyu Lu, Hongyun Wang, Alice Loo, Xiamei Zhang, Guizhi Yang, Colleen Kowal, Scott Delach, Ye Wang, Silvia Goldoni, William D. Hastings, Karrie Wong, Hui Gao, Matthew J. Meyer, Susan E. Moody, Matthew J. LaMarche, Jeffrey A. Engelman, Juliet Williams, Peter S. Hammerman, Tinya J. Abrams, Morvarid Mohseni, Giordano Caponigro, Huai‐Xiang Hao

    出版 2020
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  12. 12
    Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

    Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors 由 Jeffrey T. Bagdanoff, Zhouliang Chen, Michael Acker, Yingnan Chen, Homan Chan, Michaël Doré, Brant Firestone, Michelle Fodor, Jorge Fortanet, Murphy Hentemann, Mitsunori Kato, Robert Koenig, Laura R. LaBonte, Shumei Liu, Morvarid Mohseni, Rukundo Ntaganda, Patrick Sarver, Troy Smith, Martin Sendzik, Travis Stams, Stan Spence, Christopher Towler, Hongyun Wang, Ping Wang, Sarah Williams, Matthew J. LaMarche

    出版 2019
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  13. 13
    AZD9150, a next-generation antisense oligonucleotide inhibitor of <i>STAT3</i> with early evidence of clinical activity in lymphoma and lung cancer

    AZD9150, a next-generation antisense oligonucleotide inhibitor of <i>STAT3</i> with early evidence of clinical activity in lymphoma and lung cancer 由 David S. Hong, Razelle Kurzrock, Youngsoo Kim, Richard Woessner, Anas Younes, John Nemunaitis, Nathan Fowler, Tianyuan Zhou, Joanna Schmidt, Minji Jo, Samantha J. Lee, Mason Yamashita, Steven G. Hughes, Luis Fayad, Sarina A. Piha‐Paul, Murali V.P. Nadella, Morvarid Mohseni, Deborah Lawson, Corinne Reimer, David C. Blakey, Xiaokun Xiao, Jeff Hsu, Alexey S. Revenko, Brett P. Monia, A. Robert MacLeod

    出版 2015
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  14. 14
    Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers

    Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers 由 Huai‐Xiang Hao, Hongyun Wang, Chen Liu, Steven Kovats, Roberto Velazquez, Hengyu Lu, Bhavesh Pant, Matthew D. Shirley, Matthew J. Meyer, Minying Pu, Joanne Lim, Michael S. Fleming, LeighAnn Alexander, Ali Farsidjani, Matthew J. LaMarche, Susan E. Moody, Serena J. Silver, Giordano Caponigro, Darrin D. Stuart, Tinya J. Abrams, Peter S. Hammerman, Juliet Williams, Jeffrey A. Engelman, Silvia Goldoni, Morvarid Mohseni

    出版 2019
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  15. 15
    6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

    6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors 由 Patrick Sarver, Michael Acker, Jeffrey T. Bagdanoff, Zhouliang Chen, Yingnan Chen, Homan Chan, Brant Firestone, Michelle Fodor, Jorge Fortanet, Huai-Xiang Hao, Murphy Hentemann, Mitsunori Kato, Robert Koenig, Laura R. LaBonte, Gang Liu, Shumei Liu, Chen Liu, Eric McNeill, Morvarid Mohseni, Martin Sendzik, Travis Stams, Stan Spence, Victoriano Tamez, Ritesh Tichkule, Christopher Towler, Hongyun Wang, Ping Wang, Sarah Williams, Bing Yu, M Lamarche

    出版 2019
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  16. 16
    SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors

    SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors 由 Leila Dardaei, Hui Qin Wang, Manrose Singh, Paul Fordjour, Katherine X Shaw, Satoshi Yoda, Gráinne Kerr, Kristine Yu, Jinsheng Liang, Yichen Cao, Yan Chen, Michael S. Lawrence, Adam Langenbucher, Justin F. Gainor, Luc Friboulet, Ibiayi Dagogo‐Jack, David T. Myers, Emma Labrot, David A. Ruddy, Melissa Parks, Dana Lee, Richard H. DiCecca, Susan E. Moody, Huai-Xiang Hao, Morvarid Mohseni, Matthew J. LaMarche, Juliet Williams, Keith Hoffmaster, Giordano Caponigro, Alice T. Shaw, Aaron N. Hata, Cyril H. Benes, Fang Li, Jeffrey A. Engelman

    出版 2018
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  17. 17
    SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms

    SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms 由 Ye Wang, Morvarid Mohseni, Angelo L. Grauel, Javier Estrada, Wei Guan, Simon Liang, Jiyoung Choi, Minying Pu, Dongshu Chen, Tyler Laszewski, Stephanie Schwartz, Jane Gu, Leandra Mansur, Tyler Burks, Lauren K. Brodeur, Roberto Velazquez, Steve G. Kovats, Bhavesh Pant, Giri Buruzula, Emily Deng, Julie Chen, Farid Sari‐Sarraf, Christina Dornelas, Malini Varadarajan, Haiyan Yu, Chen Liu, Joanne Lim, Huai-Xiang Hao, Xiaomo Jiang, Anthony S. Malamas, Matthew J. LaMarche, Felipe C. Geyer, Margaret E. McLaughlin, Carlotta Costa, Joel P. Wagner, David A. Ruddy, Pushpa Jayaraman, Nathaniel D. Kirkpatrick, Pu Zhang, Oleg Iartchouk, Kimberly Aardalen, Viviana Cremasco, Glenn Dranoff, Jeffrey A. Engelman, Serena J. Silver, Hongyun Wang, William D. Hastings, Silvia Goldoni

    出版 2021
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