Torthaí cuardaigh - Mikhila Mahendra

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  1. 1
    Combined KRAS<sup>G12C</sup>and SOS1 inhibition enhances and extends the anti-tumor response in KRAS<sup>G12C</sup>-driven cancers by addressing intrinsic and acquired resistance

    Combined KRAS<sup>G12C</sup>and SOS1 inhibition enhances and extends the anti-tumor response in KRAS<sup>G12C</sup>-driven cancers by addressing intrinsic and acquired resistance de réir Venu Thatikonda, Hengyu Lu, Sabine Jurado, Kaja Kostyrko, Christopher A. Bristow, Karin Bosch, Ningping Feng, Sisi Gao, Daniel Gerlach, Michael Gmachl, Simone Lieb, Astrid Jeschko, Annette A. Machado, Ethan D. Marszalek, Mikhila Mahendra, Philipp A. Jaeger, Alexey V. Sorokin, Sandra J. Strauss, Francesca Trapani, Scott Kopetz, Christopher P. Vellano, Mark Petronczki, Norbert Kraut, Timothy P. Heffernan, Joseph R. Marszalek, Mark Pearson, Irene C. Waizenegger, Marco H. Hofmann

    Foilsithe / Cruthaithe 2023
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  2. 2
    Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistance

    Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistance de réir Venu Thatikonda, Hengyu Lyu, Sabine Jurado, Kaja Kostyrko, Christopher A. Bristow, Christoph Albrecht, Donát Alpár, Heribert Arnhof, Oliver Bergner, Karin Bosch, Ningping Feng, Sisi Gao, Daniel Gerlach, Michael Gmachl, Melanie Hinkel, Simone Lieb, Astrid Jeschko, Annette A. Machado, Thomas Madensky, Ethan D. Marszalek, Mikhila Mahendra, Gabriella Melo‐Zainzinger, Jessica M. Molkentine, Philipp A. Jaeger, David H. Peng, Robyn L. Schenk, Alexey V. Sorokin, Sandra J. Strauss, Francesca Trapani, Scott Kopetz, Christopher P. Vellano, Mark Petronczki, Norbert Kraut, Timothy P. Heffernan, Joseph R. Marszalek, Mark Pearson, Irene C. Waizenegger, Marco H. Hofmann

    Foilsithe / Cruthaithe 2024
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  3. 3
    Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

    Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials de réir Timothy A. Yap, Naval Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric‐Bernstam, Hagop M. Kantarjian, Farhad Ravandi, Meghan Collins, Maria Emilia Di Francesco, Ecaterina E. Dumbrava, Siqing Fu, Sisi Gao, Jason Gay, Sonal Gera, Jing Han, David S. Hong, Elias Jabbour, Zhenlin Ju, Daniel D. Karp, Alessia Lodi, Jennifer R. Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A. Piha‐Paul, Jordi Rodón, Carolina Salguero, Koji Sasaki, Anand Kumar Singh, Vivek Subbiah, Apostolia M. Tsimberidou, Quanyun A. Xu, Musa Yılmaz, Qi Zhang, Yuan Li, Christopher A. Bristow, Meenakshi B. Bhattacharjee, Stefano Tiziani, Timothy P. Heffernan, Christopher P. Vellano, Philip Jones, Cobi J. Heijnen, Annemieke Kavelaars, Joseph R. Marszalek, Marina Konopleva

    Foilsithe / Cruthaithe 2023
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  4. 4
    Androgen receptor activity promotes resistance to BRAF-targeted melanoma therapy

    Androgen receptor activity promotes resistance to BRAF-targeted melanoma therapy de réir Jennifer A. Wargo, Christopher P. Vellano, Michael White, Miles C. Andrews, Joseph R. Daniele, Mark Titus, Gabriel O Ologun, Alexandria P. Cogdill, Golnaz Morad, Jennifer L. McQuade, Rohit Thakur, Peter A. Prieto, Alexander J. Lazar, Md Abdul Wadud Khan, Beth A. Helmink, Michael A. Davies, Rodabe N. Amaria, Jeffrey J. Kovacs, Scott E. Woodman, Hussein A. Tawbi, Sapna P. Patel, Patrick Hwu, Michael Peoples, Jeffrey Lee, Zachary A. Cooper, Haifeng Zhu, Guanghui Gao, Jeffrey E. Gershenwald, Anthony Lucci, Emily Z. Keung, Merrick I. Ross, Khalida Wani, Michael T. Tetzlaff, Lauren E. Haydu, Mikhila Mahendra, XioYan Ma, Christopher J. Logothetis, Zachary Kulstad, Sadie Johnson, Courtney W. Hudgens, Ningping Feng, Lorenzo Federico, Elizabeth M. Burton, Swathi Arur, Timothy P. Heffernan, Joseph R. Marszalek

    Foilsithe / Cruthaithe 2020
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  5. 5
    Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy

    Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy de réir Christopher P. Vellano, Michael G. White, Miles C. Andrews, Manoj Chelvanambi, Russell G. Witt, Joseph R. Daniele, Mark Titus, Jennifer L. McQuade, Fabio Conforti, Elizabeth M. Burton, Matthew Lastrapes, Gabriel O Ologun, Alexandria P. Cogdill, Golnaz Morad, Peter A. Prieto, Alexander J. Lazar, Yanshuo Chu, Guangchun Han, M.A. Wadud Khan, Beth A. Helmink, Michael A. Davies, Rodabe N. Amaria, Jeffrey J. Kovacs, Scott E. Woodman, Sapna P. Patel, Patrick Hwu, Michael Peoples, Jeffrey E. Lee, Zachary A. Cooper, Haifeng Zhu, Guang R. Gao, Hiya Banerjee, Mike Lau, Jeffrey E. Gershenwald, Anthony Lucci, Emily Z. Keung, Merrick I. Ross, Laura Pala, Eleonora Pagan, Rossana Lazcano Segura, Qian Liu, Mikayla Borthwick, Eric Lau, Melinda S. Yates, Shannon N. Westin, Khalida Wani, Michael T. Tetzlaff, Lauren E. Haydu, Mikhila Mahendra, Xiao-Yan Ma, Christopher J. Logothetis, Zachary Kulstad, Sarah Johnson, Courtney W. Hudgens, Ningping Feng, Lorenzo Federico, Georgina V. Long, P. Andrew Futreal, Swathi Arur, Hussein A. Tawbi, Amy E. Moran, Linghua Wang, Timothy P. Heffernan, Joseph R. Marszalek, Jennifer A. Wargo

    Foilsithe / Cruthaithe 2022
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