Výsledky vyhledávání - Michelle L. Stewart

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  1. 1
    The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

    The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer Autor Michelle L. Stewart, Emiko Fire, Amy E. Keating, Loren D. Walensky

    Vydáno 2010
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  2. 2
    A Competitive Stapled Peptide Screen Identifies a Selective Small Molecule that Overcomes MCL-1-Dependent Leukemia Cell Survival

    A Competitive Stapled Peptide Screen Identifies a Selective Small Molecule that Overcomes MCL-1-Dependent Leukemia Cell Survival Autor Nicole A. Cohen, Michelle L. Stewart, Evripidis Gavathiotis, Jared L. Tepper, Susanne R. Bruekner, Brian Koss, Joseph T. Opferman, Loren D. Walensky

    Vydáno 2012
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  3. 3
    <i>KRAS</i> Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine

    <i>KRAS</i> Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine Autor Michelle L. Stewart, Pablo Tamayo, Andrew J. Wilson, Stephanie Wang, Daniel Y. Chang, Jong W. Kim, Dineo Khabele, Alykhan F. Shamji, Stuart L. Schreiber

    Vydáno 2015
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  4. 4
    A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

    A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers Autor James L. LaBelle, Samuel G. Katz, Gregory H. Bird, Evripidis Gavathiotis, Michelle L. Stewart, Chelsea E. Lawrence, Jill K. Fisher, Marina Godes, Kenneth L. Pitter, Andrew L. Kung, Loren D. Walensky

    Vydáno 2012
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  5. 5
    Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism

    Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism Autor Lauren A. Barclay, Thomas E. Wales, Thomas P. Garner, Franziska Wachter, Susan Lee, Rachel M. Guerra, Michelle L. Stewart, Craig R. Braun, Gregory H. Bird, Evripidis Gavathiotis, John R. Engen, Loren D. Walensky

    Vydáno 2015
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  6. 6
    Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib

    Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib Autor Nikhil Wagle, Brian C. Grabiner, Eliezer M. Van Allen, Eran Hodis, Susanna Jacobus, Jeffrey G. Supko, Michelle L. Stewart, Toni K. Choueiri, Leena Gandhi, James M. Cleary, Aymen Elfiky, Mary Ellen Taplin, Edward C. Stack, Sabina Signoretti, Massimo Loda, Geoffrey I. Shapiro, David M. Sabatini, Eric S. Lander, Stacey Gabriel, Philip W. Kantoff, Levi A. Garraway, Jonathan E. Rosenberg

    Vydáno 2014
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  7. 7
    DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with<i>In Silico</i>Analysis to Identify Novel Therapeutic Targets

    DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with<i>In Silico</i>Analysis to Identify Novel Therapeutic Targets Autor Allison R. Hanaford, Tenley C. Archer, Antoinette Price, Ulf D. Kahlert, Jarek Maciaczyk, Guido Nikkhah, Jong Wook Kim, Tobias Ehrenberger, Paul A. Clemons, Vlado Dančík, Brinton Seashore‐Ludlow, Vasanthi S. Viswanathan, Michelle L. Stewart, Matthew G. Rees, Alykhan Shamji, Stuart L. Schreiber, Ernest Fraenkel, Scott L. Pomeroy, Jill P. Mesirov, Pablo Tamayo, Charles G. Eberhart, Eric H. Raabe

    Vydáno 2016
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  8. 8
    Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface

    Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface Autor Uddhav Kumar Shigdel, Seung‐Joo Lee, Mathew E. Sowa, Brian R. Bowman, Keith Robison, Minyun Zhou, Khian Hong Pua, Dylan T. Stiles, Joshua A. V. Blodgett, Daniel Udwary, Andrew T. Rajczewski, Alan S. Mann, Siavash Mostafavi, Tara Hardy, Sukrat Arya, Zhigang Weng, Michelle L. Stewart, Kyle Kenyon, Jay P. Morgenstern, Ende Pan, Daniel C. Gray, Roy M. Pollock, Andrew M. Fry, Richard D. Klausner, Sharon A. Townson, Gregory L. Verdine

    Vydáno 2020
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  9. 9
    An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

    An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules Autor Amrita Basu, Nicole E. Bodycombe, Jaime H. Cheah, Edmund V. Price, Ke Liu, Giannina I. Schaefer, Richard Y. Ebright, Michelle L. Stewart, Daisuke Ito, Stephanie Wang, Abigail Bracha, Ted Liefeld, Mathias J. Wawer, Joshua C. Gilbert, Andrew J. Wilson, Nicolas Stransky, Gregory V. Kryukov, Vlado Dančík, Jordi Barretina, Levi A. Garraway, C. Suk-Yee Hon, Benito Muñoz, Joshua A. Bittker, Brent R. Stockwell, Dineo Khabele, Andrew M. Stern, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber

    Vydáno 2013
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  10. 10
    Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States

    Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States Autor Jong Wook Kim, Omar O. Abudayyeh, Huwate Yeerna, Chen‐Hsiang Yeang, Michelle L. Stewart, Russell W. Jenkins, Shunsuke Kitajima, David J. Konieczkowski, Kate Medetgul-Ernar, Taylor B. Cavazos, Clarence K. Mah, Stephanie Ting, Eliezer M. Van Allen, Ofir Cohen, John McDermott, Emily Damato, Andrew J. Aguirre, Jonathan Liang, Arthur Liberzon, Gabriella Alexe, John G. Doench, Mahmoud Ghandi, Francisca Vázquez, Barbara A. Weir, Aviad Tsherniak, Aravind Subramanian, Karina Meneses-Cime, Jason Y. Park, Paul A. Clemons, Levi A. Garraway, David Thomas, Jesse S. Boehm, David A. Barbie, William C. Hahn, Jill P. Mesirov, Pablo Tamayo

    Vydáno 2017
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