Search Results - Michael Sasner

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  1. 1
    Toward more predictive genetic mouse models of Alzheimer's disease

    Toward more predictive genetic mouse models of Alzheimer's disease by Kristen D. Onos, Stacey J. Sukoff Rizzo, Gareth R. Howell, Michael Sasner

    Published 2015
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  2. 2
    Gene replacement‐Alzheimer's disease (GR‐AD): Modeling the genetics of human dementias in mice

    Gene replacement‐Alzheimer's disease (GR‐AD): Modeling the genetics of human dementias in mice by Kellie Benzow, Kul Karanjeet, Adrian L. Oblak, Gregory W. Carter, Michael Sasner, Michael D. Koob

    Published 2024
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  3. 3
    The APOEε3/ε4 Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice

    The APOEε3/ε4 Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice by Kate E. Foley, Amanda A. Hewes, Dylan Garceau, Kevin P. Kotredes, Gregory W. Carter, Michael Sasner, Gareth R. Howell

    Published 2022
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  4. 4
    Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease

    Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease by Ravi S. Pandey, Matthias Arnold, Richa Batra, Jan Krumsiek, Kevin P. Kotredes, Dylan Garceau, Harriet M. Williams, Michael Sasner, Gareth R. Howell, Rima Kaddurah‐Daouk, Gregory W. Carter

    Published 2024
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  5. 5
    A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

    A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease by Christoph Preuß, Ravi S. Pandey, Erin Piazza, Alexander D. Fine, Aslı Uyar, Thanneer M. Perumal, Dylan Garceau, Kevin P. Kotredes, Harriet M. Williams, Lara M. Mangravite, Bruce T. Lamb, Adrian L. Oblak, Gareth R. Howell, Michael Sasner, Benjamin A. Logsdon, Gregory W. Carter

    Published 2020
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  6. 6
    Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease

    Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease by Sebastiaan De Schepper, Judy Z. Ge, Gerard Crowley, Laís S. S. Ferreira, Dylan Garceau, Christina E. Toomey, Dimitra Sokolova, Javier Rueda‐Carrasco, Sun‐Hye Shin, Jung‐Seok Kim, Thomas Childs, Tammaryn Lashley, Jemima J. Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, Soyon Hong

    Published 2023
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  7. 7
    Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis

    Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis by Leslie O. Goodwin, Erik Splinter, Tiffany L. Davis, Rachel Urban, Hao He, Robert E. Braun, Elissa J. Chesler, Vivek Kumar, Max van Min, Juliet Ndukum, Vivek M. Philip, Laura G. Reinholdt, Karen L. Svenson, Jacqueline K. White, Michael Sasner, Cathleen Lutz, Stephen A. Murray

    Published 2019
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  8. 8
    Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD

    Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD by Adrian L. Oblak, Stefânia Forner, Paul R. Territo, Michael Sasner, Gregory W. Carter, Gareth R. Howell, Stacey J. Sukoff Rizzo, Benjamin A. Logsdon, Lara M. Mangravite, A Mortazavi, David Baglietto‐Vargas, Kim N. Green, Grant R. MacGregor, Marcelo A. Wood, Andrea J. Tenner, Frank M. LaFerla, Bruce T. Lamb

    Published 2020
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  9. 9
    Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H

    Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H by Kevin P. Kotredes, Adrian L. Oblak, Ravi S. Pandey, Peter Bor‐Chian Lin, Dylan Garceau, Harriet M. Williams, Aslı Uyar, Rita O’Rourke, Sarah O’Rourke, Cynthia M. Ingraham, Daria Bednarczyk, Melisa Belanger, Zackary A. Cope, Kate E. Foley, Benjamin A. Logsdon, Lara M. Mangravite, Stacey J. Sukoff Rizzo, Paul R. Territo, Gregory W. Carter, Michael Sasner, Bruce T. Lamb, Gareth R. Howell

    Published 2021
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  10. 10
    Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study

    Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study by Adrian L. Oblak, Peter Bor‐Chian Lin, Kevin P. Kotredes, Ravi S. Pandey, Dylan Garceau, Harriet M. Williams, Aslı Uyar, Rita O’Rourke, Sarah O’Rourke, Cynthia M. Ingraham, Daria Bednarczyk, Melisa Belanger, Zackary A. Cope, Gabriela Little, Sean-Paul G. Williams, Carl T. Ash, Adam Bleckert, Tim Ragan, Benjamin A. Logsdon, Lara M. Mangravite, Stacey J. Sukoff Rizzo, Paul R. Territo, Gregory W. Carter, Gareth R. Howell, Michael Sasner, Bruce T. Lamb

    Published 2021
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  11. 11
    Characterizing molecular and synaptic signatures in mouse models of late‐onset Alzheimer's disease independent of amyloid and tau pathology

    Characterizing molecular and synaptic signatures in mouse models of late‐onset Alzheimer's disease independent of amyloid and tau pathology by Kevin P. Kotredes, Ravi S. Pandey, Scott C. Persohn, Kierra Elderidge, Charles P. Burton, Ethan W. Miner, Kathryn A. Haynes, Diogo Francisco da Silva dos Santos, Sean-Paul G. Williams, Nicholas S. Heaton, Cynthia M. Ingraham, Christopher Lloyd, Dylan Garceau, Rita O’Rourke, Sarah E. Herrick, Claudia Rangel‐Barajas, Surendra Maharjan, Nian Wang, Michael Sasner, Bruce T. Lamb, Paul R. Territo, Stacey J. Sukoff Rizzo, Gregory W. Carter, Gareth R. Howell, Adrian L. Oblak

    Published 2024
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  12. 12
    Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia

    Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia by Dan Xia, Steve Lianoglou, Thomas Sandmann, Meredith Calvert, Jung H. Suh, Elliot R. Thomsen, Jason C. Dugas, Michelle E. Pizzo, Sarah L. DeVos, Timothy Earr, Chia-Ching Lin, Sonnet S. Davis, Connie Ha, Amy Wing-Sze Leung, Hoang N. Nguyen, Roni Chau, Ernie Yulyaningsih, Isabel Álvarez, Hilda Solanoy, Shababa T. Masoud, Chun-chi Liang, Karin Lin, Giuseppe Astarita, Nathalie Khoury, Joy Yu Zuchero, Robert G. Thorne, Kevin Shen, Stephanie R. Miller, Jorge J. Palop, Dylan Garceau, Michael Sasner, Jennifer D. Whitesell, Julie A. Harris, Selina Hummel, Johannes Gnörich, Karin Wind, Lea H. Kunze, Artem Zatcepin, Matthias Brendel, Michael Willem, Christian Haass, Daniel Barnett, Till S. Zimmer, Anna G. Orr, Kimberly Scearce‐Levie, Joseph W. Lewcock, Gilbert Di Paolo, Pascal E. Sanchez

    Published 2022
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