نتائج البحث - Michael Reilly

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  1. 1
    An evaluation of ultrasound imaging for identificationof lumbar intervertebral level

    An evaluation of ultrasound imaging for identificationof lumbar intervertebral level حسب G. Furness, Michael Reilly, S. Kuchi

    منشور في 2002
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    Artigo
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  2. 2
    Characterization of GSK′963: a structurally distinct, potent and selective inhibitor of RIP1 kinase

    Characterization of GSK′963: a structurally distinct, potent and selective inhibitor of RIP1 kinase حسب SB Berger, Philip A. Harris, Rakesh Nagilla, Viera Kasparcova, Sandra C. Hoffman, Brandon Swift, Lauren Dare, Michelle C. Schaeffer, Carol A. Capriotti, Michael T. Ouellette, BW King, David D. Wisnoski, Julie A. Cox, Michael Reilly, RW Marquis, John Bertin, PJ Gough

    منشور في 2015
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    Artigo
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  3. 3
    Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of <scp>RIPK</scp>1 inhibitor <scp>GSK</scp>2982772 in healthy volunteers

    Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of <scp>RIPK</scp>1 inhibitor <scp>GSK</scp>2982772 in healthy volunteers حسب Kathleen Weisel, Nicola Scott, Debra Tompson, Bartholomew J. Votta, Sujith Madhavan, Kat Povey, Allen Wolstenholme, Monica Simeoni, Todd Rudo, Lauren E. Richards‐Peterson, Tarjinder Sahota, J. Gene Wang, John D. Lich, Joshua N. Finger, Adeline Verticelli, Michael Reilly, Peter J. Gough, Philip A. Harris, John Bertin, Mei‐Lun Wang

    منشور في 2017
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    Artigo
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  4. 4
    Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

    Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 حسب Alina Mares, Afjal H. Miah, Ian E. Smith, M.D. Rackham, Aditya R. Thawani, Jenni Cryan, Pamela A. Haile, Bartholomew J. Votta, Allison M. Beal, Carol A. Capriotti, Michael Reilly, Don T. Fisher, Nico Zinn, Marcus Bantscheff, Thomas T. MacDonald, Anna Vossenkämper, Phoebe Dace, Ian Churcher, Andrew B. Benowitz, Gillian F. Watt, Jane Denyer, Paul Scott‐Stevens, John D. Harling

    منشور في 2020
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    Artigo
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  5. 5
    Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer

    Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer حسب Philip A. Harris, Jill M. Marinis, John D. Lich, Scott B. Berger, Anirudh Chirala, Julie A. Cox, Patrick M. Eidam, Joshua N. Finger, Peter J. Gough, Jae Uk Jeong, James Kang, Viera Kasparcova, Lara K. Leister, Mukesh Mahajan, George Miller, Rakesh Nagilla, Michael T. Ouellette, Michael Reilly, Alan R. Rendina, Elizabeth J. Rivera, Helen H. Sun, James H. Thorpe, Rachel D. Totoritis, Wei Wang, Dongling Wu, Daohua Zhang, John Bertin, Robert W. Marquis

    منشور في 2019
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    Artigo
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  6. 6
    RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer

    RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer حسب Wei Wang, Jill M. Marinis, Allison M. Beal, Shivraj Savadkar, Yue Wu, Mohammed I. Khan, Pardeep S. Taunk, Nan Wu, Wenyu Su, Jingjing Wu, Aarif Ahsan, Emma Kurz, Ting Chen, Inedouye Yaboh, Fei Li, Johana Gutierrez, Brian Diskin, Mautin Hundeyin, Michael Reilly, John D. Lich, Philip A. Harris, Mukesh Mahajan, James H. Thorpe, Pamela Nassau, J. Mosley, Joshua Leinwand, Juan Andres Kochen Rossi, Ankita Mishra, Berk Aykut, Michael W. Glacken, Atsuo Ochi, Narendra Verma, Jacqueline I. Kim, Varshini Vasudevaraja, Dennis O. Adeegbe, Christina Almonte, Ece Bagdatlioglu, Deirdre Jill Cohen, Kwok‐Kin Wong, John Bertin, George Miller

    منشور في 2018
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  7. 7
    Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[<i>d</i>]thiazol-5-ylamino)-6-(<i>tert</i>-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases

    Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[<i>d</i>]thiazol-5-ylamino)-6-(<i>tert</i>-butylsulfonyl)quinaz... حسب Pamela A. Haile, Linda Casillas, Bartholomew J. Votta, Gren Z. Wang, Adam K. Charnley, Xiaoyang Dong, Michael J. Bury, Joseph J. Romano, John F. Mehlmann, Bryan W. King, Karl F. Erhard, Charles R. Hanning, David B. Lipshutz, Biva M. Desai, Carol A. Capriotti, Michelle C. Schaeffer, Scott B. Berger, Mukesh Mahajan, Michael Reilly, Rakesh Nagilla, Elizabeth J. Rivera, Helen H. Sun, John K. Kenna, Allison M. Beal, Michael T. Ouellette, Mike Kelly, Gillian Stemp, M.A. Convery, Anna Vossenkämper, Thomas T. MacDonald, Peter J. Gough, John Bertin, Robert W. Marquis

    منشور في 2019
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    Artigo
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  8. 8
    Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase

    Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase حسب Philip A. Harris, Nicolas Faucher, Nicolas George, Patrick M. Eidam, Bryan W. King, Gemma V. White, Niall A. Anderson, Deepak Bandyopadhyay, Allison M. Beal, Véronique Bénéton, Scott B. Berger, Nino Campobasso, Sébastien Campos, Carol A. Capriotti, Julie A. Cox, Alain Daugan, Frédéric Donche, Marie-Hélène Fouchet, Joshua N. Finger, Brad J. Geddes, Peter J. Gough, Pascal Grondin, Bonnie L. Hoffman, Sandra J. Hoffman, Susan E. Hutchinson, Jae Uk Jeong, Émilie Jigorel, P. Lamoureux, Lara K. Leister, John D. Lich, Mukesh Mahajan, Jamel Meslamani, J. Mosley, Rakesh Nagilla, Pamela Nassau, Sze‐Ling Ng, Michael T. Ouellette, Kishore Kumar Pasikanti, Florent Potvain, Michael Reilly, Elizabeth J. Rivera, Stéphane Sautet, Michelle C. Schaeffer, Clark A. Sehon, Helen H. Sun, James H. Thorpe, Rachel D. Totoritis, Paris Ward, Natalie Wellaway, David D. Wisnoski, James M. Woolven, John Bertin, Robert W. Marquis

    منشور في 2019
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