Kết quả tìm kiếm - Michael Offin

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  1. 1
    Tumor-Agnostic Drug Development

    Tumor-Agnostic Drug Development Bằng Michael Offin, Dazhi Liu, Alexander Drilon

    Được phát hành 2018
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    Artigo
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  2. 2
    Entrectinib: an orally available, selective tyrosine kinase inhibitor for the treatment of <em>NTRK</em>, <em>ROS1</em>, and <em>ALK</em> fusion-positive solid tumors

    Entrectinib: an orally available, selective tyrosine kinase inhibitor for the treatment of <em>NTRK</em>, <em>ROS1</em>, and <em>ALK</em> fusion... Bằng Dazhi Liu, Michael Offin, Stephen Harnicar, Bob T. Li, Alexander Drilon

    Được phát hành 2018
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    Revisão
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  3. 3
    Invasive Mucinous Adenocarcinomas With Spatially Separate Lung Lesions: Analysis of Clonal Relationship by Comparative Molecular Profiling

    Invasive Mucinous Adenocarcinomas With Spatially Separate Lung Lesions: Analysis of Clonal Relationship by Comparative Molecular Profiling Bằng Soo‐Ryum Yang, Jason C. Chang, Charles Leduc, Kay See Tan, Snjezana Doğan, Ryma Benayed, Laetitia Borsu, Michael Offin, Alexander Drilon, William D. Travis, Maria E. Arcila, Marc Ladanyi, Natasha Rekhtman

    Được phát hành 2021
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    Artigo
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  4. 4
    Molecular Characterization of Peritoneal Mesotheliomas

    Molecular Characterization of Peritoneal Mesotheliomas Bằng Michael Offin, Soo‐Ryum Yang, Jacklynn V. Egger, Gowtham Jayakumaran, Rowanne S Spencer, Jessica Lopardo, Garrett M. Nash, Andrea Cercek, William D. Travis, Mark G. Kris, Marc Ladanyi, Jennifer L. Sauter, Marjorie G. Zauderer

    Được phát hành 2021
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    Artigo
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  5. 5
    Acquired <i>MET</i> Exon 14 Alteration Drives Secondary Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in <i>EGFR</i> -Mutated Lung Cancer

    Acquired <i>MET</i> Exon 14 Alteration Drives Secondary Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in <i>EGFR</i> -Mutated Lung Cancer Bằng Ken Suzawa, Michael Offin, Adam J. Schoenfeld, Andrew J. Plodkowski, Igor Odintsov, Daniel Lu, William W. Lockwood, Maria E. Arcila, Charles M. Rudin, Alexander Drilon, Helena A. Yu, Gregory J. Riely, Romel Somwar, Marc Ladanyi

    Được phát hành 2019
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    Artigo
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  6. 6
    Radiation pneumonitis in lung cancer patients treated with chemoradiation plus durvalumab

    Radiation pneumonitis in lung cancer patients treated with chemoradiation plus durvalumab Bằng Narek Shaverdian, Maria Thor, Annemarie F. Shepherd, Michael Offin, Andrew Jackson, Abraham J. Wu, Daphna Y. Gelblum, Ellen Yorke, Charles B. Simone, Jamie E. Chaft, Matthew D. Hellmann, Daniel R. Gomez, Andreas Rimner, Joseph O. Deasy

    Được phát hành 2020
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    Artigo
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  7. 7
    Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with <i>EGFR</i>-Mutant Lung Cancers

    Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with <i>EGFR</i>-Mutant Lung Cancers Bằng Michael Offin, Hira Rizvi, Megan Tenet, Ai Ni, Francisco Sánchez-Vega, Bob T. Li, Alexander Drilon, Mark G. Kris, Charles M. Rudin, Nikolaus Schultz, Maria E. Arcila, Marc Ladanyi, Gregory J. Riely, Helena A. Yu, Matthew D. Hellmann

    Được phát hành 2018
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    Artigo
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  8. 8
    Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers

    Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers Bằng Morana Vojnic, Daisuke Kubota, Christopher Kurzatkowski, Michael Offin, Ken Suzawa, Ryma Benayed, Adam J. Schoenfeld, Andrew J. Plodkowski, John T. Poirier, Charles M. Rudin, Mark G. Kris, Neal Rosen, Helena A. Yu, Gregory J. Riely, Maria E. Arcila, Romel Somwar, Marc Ladanyi

    Được phát hành 2019
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    Artigo
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  9. 9
    Clinical outcomes, local–regional control and the role for metastasis-directed therapies in stage III non-small cell lung cancers treated with chemoradiation and durvalumab

    Clinical outcomes, local–regional control and the role for metastasis-directed therapies in stage III non-small cell lung cancers treated with chemoradiation and durvalumab Bằng Michael Offin, Narek Shaverdian, Andreas Rimner, Stephanie Lobaugh, Annemarie F. Shepherd, Charles B. Simone, Daphna Y. Gelblum, Abraham J. Wu, Nancy Y. Lee, Mark G. Kris, Charles M. Rudin, Zhigang Zhang, Matthew D. Hellmann, Jamie E. Chaft, Daniel R. Gomez

    Được phát hành 2020
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    Artigo
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  10. 10
    Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14–mutant Non–small Cell Lung Cancer

    Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14–mutant Non–small Cell Lung Cancer Bằng Ken Suzawa, Michael Offin, Daniel Lu, Christopher Kurzatkowski, Morana Vojnic, Roger S. Smith, Joshua K. Sabari, Huichun Tai, Marissa S. Mattar, Inna Khodos, Elisa de Stanchina, Charles M. Rudin, Mark G. Kris, Maria E. Arcila, William W. Lockwood, Alexander Drilon, Marc Ladanyi, Romel Somwar

    Được phát hành 2018
    lấy văn bản
    Artigo
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  11. 11
    Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes

    Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes Bằng Michael Offin, Joseph M. Chan, Megan Tenet, Hira Rizvi, Ronglai Shen, Gregory J. Riely, Natasha Rekhtman, Yahya Daneshbod, Álvaro Quintanal-Villalonga, Alexander Penson, Matthew D. Hellmann, Maria E. Arcila, Marc Ladanyi, Dana Pe’er, Mark G. Kris, Charles M. Rudin, Helena A. Yu

    Được phát hành 2019
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    Artigo
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  12. 12
    High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden

    High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden Bằng Ryma Benayed, Michael Offin, Kerry Mullaney, Purvil Sukhadia, Kelly Rios, Patrice Desmeules, Ryan Ptashkin, Helen Won, Jason C. Chang, Darragh Halpenny, Alison M. Schram, Charles M. Rudin, David M. Hyman, Maria E. Arcila, Michael F. Berger, Ahmet Zehir, Mark G. Kris, Alexander Drilon, Marc Ladanyi

    Được phát hành 2019
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    Artigo
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  13. 13
    Rb Tumor Suppressor in Small Cell Lung Cancer: Combined Genomic and IHC Analysis with a Description of a Distinct Rb-Proficient Subset

    Rb Tumor Suppressor in Small Cell Lung Cancer: Combined Genomic and IHC Analysis with a Description of a Distinct Rb-Proficient Subset Bằng Christopher A. Febres‐Aldana, Jason C. Chang, Ryan Ptashkin, Yuhan Wang, Erika Gedvilaite, Marina K. Baine, William D. Travis, Katia Ventura, Francis M. Bodd, Helena A. Yu, Álvaro Quintanal-Villalonga, W. Victoria Lai, Jacklynn V. Egger, Michael Offin, Marc Ladanyi, Charles M. Rudin, Natasha Rekhtman

    Được phát hành 2022
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    Editorial
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  14. 14
    Acquired <i>ALK</i> and <i>RET</i> Gene Fusions as Mechanisms of Resistance to Osimertinib in <i>EGFR</i>-Mutant Lung Cancers

    Acquired <i>ALK</i> and <i>RET</i> Gene Fusions as Mechanisms of Resistance to Osimertinib in <i>EGFR</i>-Mutant Lung Cancers Bằng Michael Offin, Romel Somwar, Natasha Rekhtman, Ryma Benayed, Jason C. Chang, Andrew J. Plodkowski, Allan J.W. Lui, Juliana Eng, Marc K. Rosenblum, Bob T. Li, Gregory J. Riely, Charles M. Rudin, Mark G. Kris, William D. Travis, Alexander Drilon, Maria E. Arcila, Marc Ladanyi, Helena A. Yu

    Được phát hành 2018
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    Artigo
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  15. 15
    Comparison of Immunohistochemistry, Next-generation Sequencing and Fluorescence In Situ Hybridization for Detection of MTAP Loss in Pleural Mesothelioma

    Comparison of Immunohistochemistry, Next-generation Sequencing and Fluorescence In Situ Hybridization for Detection of MTAP Loss in Pleural Mesothelioma Bằng Christopher A. Febres‐Aldana, Jason C. Chang, Achim A. Jungbluth, Prasad S. Adusumilli, Francis M. Bodd, Denise Frosina, Jerica A. Geronimo, Enmily Hernandez, Helen Irawan, Michael Offin, Natasha Rekhtman, William D. Travis, Chad Vanderbilt, Marjorie G. Zauderer, Yanming Zhang, Marc Ladanyi, Soo‐Ryum Yang, Jennifer L. Sauter

    Được phát hành 2024
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    Artigo
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  16. 16
    Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in<i>EGFR</i>-Mutant Lung Cancer

    Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in<i>EGFR</i>-Mutant Lung Cancer Bằng Adam J. Schoenfeld, Joseph M. Chan, Daisuke Kubota, Hiroki Sato, Hira Rizvi, Yahya Daneshbod, Jason C. Chang, Paul K. Paik, Michael Offin, Maria E. Arcila, Monika A. Davare, Ujwal Shinde, Dana Pe’er, Natasha Rekhtman, Mark G. Kris, Romel Somwar, Gregory J. Riely, Marc Ladanyi, Helena A. Yu

    Được phát hành 2020
    lấy văn bản lấy văn bản
    Carta
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  17. 17
    Immunophenotype and Response to Immunotherapy of <i>RET</i>-Rearranged Lung Cancers

    Immunophenotype and Response to Immunotherapy of <i>RET</i>-Rearranged Lung Cancers Bằng Michael Offin, Robin Guo, Stephanie L. Wu, Joshua K. Sabari, Josiah D. Land, Ai Ni, Joseph Montecalvo, Darragh Halpenny, Larry W. Buie, Terry Pak, Dazhi Liu, Gregory J. Riely, Matthew D. Hellmann, Ryma Benayed, Maria E. Arcila, Mark G. Kris, Charles M. Rudin, Bob T. Li, Marc Ladanyi, Natasha Rekhtman, Alexander Drilon

    Được phát hành 2019
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    Artigo
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  18. 18
    MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by <i>ROS1</i> Fusions

    MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by <i>ROS1</i> Fusions Bằng Hiroki Sato, Adam J. Schoenfeld, Evan Siau, Yue Christine Lu, Huichun Tai, Ken Suzawa, Daisuke Kubota, Allan J.W. Lui, Besnik Qeriqi, Marissa S. Mattar, Michael Offin, Masakiyo Sakaguchi, Shinichi Toyooka, Alexander Drilon, Neal Rosen, Mark G. Kris, David B. Solit, Elisa de Stanchina, Monika A. Davare, Gregory J. Riely, Marc Ladanyi, Romel Somwar

    Được phát hành 2020
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    Artigo
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  19. 19
    Characterization of on-target adverse events caused by TRK inhibitor therapy

    Characterization of on-target adverse events caused by TRK inhibitor therapy Bằng D. Liu, James Flory, Andrew Lin, Michael Offin, Christina J. Falcon, Yonina R. Murciano‐Goroff, Ezra Rosen, Robin Guo, Ellen M. Basu, Bob T. Li, James J. Harding, Gopa Iyer, Komal Jhaveri, Mrinal M. Gounder, Neerav Shukla, Stephen S. Roberts, Julia Glade Bender, Lauren A. Kaplanis, Alison M. Schram, David M. Hyman, Alexander Drilon

    Được phát hành 2020
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    Artigo
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  20. 20
    Frequency of Brain Metastases and Multikinase Inhibitor Outcomes in Patients With RET–Rearranged Lung Cancers

    Frequency of Brain Metastases and Multikinase Inhibitor Outcomes in Patients With RET–Rearranged Lung Cancers Bằng Alexander Drilon, W. Marston Linehan, Thomas Filleron, Ai Ni, Julie Milia, Isabella Bergagnini, Vaios Hatzoglou, Vamsidhar Velcheti, Michael Offin, Bob T. Li, David P. Carbone, Benjamin Besse, Tony Mok, Mark M. Awad, Jürgen Wolf, Dwight H. Owen, D. Ross Camidge, Gregory J. Riely, Nir Peled, Mark G. Kris, Julien Mazières, Justin F. Gainor, Oliver Gautschi

    Được phát hành 2018
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    Artigo
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