Výsledky vyhledávání - Michael D. Shultz

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  1. 1
    Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939

    Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939 Autor C.A. Kirby, Atwood K. Cheung, Aleem Fazal, Michael D. Shultz, Travis Stams

    Vydáno 2012
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  2. 2
    hnRNP U Enhances Caspase-9 Splicing and Is Modulated by AKT-dependent Phosphorylation of hnRNP L

    hnRNP U Enhances Caspase-9 Splicing and Is Modulated by AKT-dependent Phosphorylation of hnRNP L Autor Ngoc Vu, Margaret A. Park, Jacqueline C. Shultz, Rachel W. Goehe, L. Alexis Hoeferlin, Michael D. Shultz, Sarah A. Smith, Kristen W. Lynch, Charles E. Chalfant

    Vydáno 2013
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  3. 3
    Impact of ventricular ectopic burden in a premature ventricular contraction–induced cardiomyopathy animal model

    Impact of ventricular ectopic burden in a premature ventricular contraction–induced cardiomyopathy animal model Autor Alex Y. Tan, Yuhning L. Hu, Jonathan Potfay, Károly Kaszala, Maureen Howren, Adam Šíma, Michael D. Shultz, Jayanthi N. Koneru, Kenneth A. Ellenbogen, José F. Huizar

    Vydáno 2015
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  4. 4
    Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase

    Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase Autor Andreas Lingel, Martin Sendzik, Ying Huang, Michael D. Shultz, John Cantwell, Michael P. Dillon, Xingnian Fu, John Fuller, Tobias Gabriel, Justin Gu, Xiangqing Jiang, Ling Li, Fang Liang, Maureen McKenna, Wei Qi, Weijun Rao, Xijun Sheng, Wei Shu, James Sutton, Benjamin R. Taft, Long Wang, Jue Zeng, Hailong Zhang, Maya Zhang, Kehao Zhao, Mika Lindvall, Dirksen E. Bussiere

    Vydáno 2016
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  5. 5
    Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor

    Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor Autor Young Shin Cho, Julian Levell, Gang Liu, Thomas R. Caferro, James Sutton, Cynthia M. Shafer, Abran Costales, James R. Manning, Qian Zhao, Martin Sendzik, Michael D. Shultz, Gregg Chenail, Julia Dooley, Brian Villalba, Ali Farsidjani, Jinyun Chen, Raviraj Kulathila, Xiaoling Xie, Stephanie Dodd, Ty Gould, Guiqing Liang, Tycho Heimbach, Kelly L. Slocum, Brant Firestone, Minying Pu, Raymond Pagliarini, Joseph D. Growney

    Vydáno 2017
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  6. 6
    Dual Allosteric Inhibition of SHP2 Phosphatase

    Dual Allosteric Inhibition of SHP2 Phosphatase Autor Michelle Fodor, Edmund V. Price, Ping Wang, Hengyu Lu, Andreea Argintaru, Zhouliang Chen, Meir Glick, Huai‐Xiang Hao, Mitsunori Kato, Robert Koenig, Jonathan R. LaRochelle, Gang Liu, Eric McNeill, Dyuti Majumdar, Gisele Nishiguchi, Lawrence Perez, Grégory Paris, Christopher M. Quinn, Timothy M. Ramsey, Martin Sendzik, Michael D. Shultz, Sarah Williams, Travis Stams, Stephen C. Blacklow, Michael Acker, Matthew J. LaMarche

    Vydáno 2018
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  7. 7
    Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

    Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor Autor Jorge Fortanet, Christine Hiu-Tung Chen, Ying-Nan P. Chen, Zhouliang Chen, Zhan Deng, Brant Firestone, Peter Fekkes, Michelle Fodor, Pascal D. Fortin, Cary Fridrich, Denise C. Grünenfelder, Samuel B. Ho, Kang Zhao, Rajesh Karki, Mitsunori Kato, Nick Keen, Laura R. LaBonte, Jay F. Larrow, François Lenoir, Gang Liu, Shumei Liu, Franco Lombardo, Dyuti Majumdar, Matthew J. Meyer, Mark Palermo, Lawrence Perez, Minying Pu, Timothy M. Ramsey, William R. Sellers, Michael D. Shultz, Travis Stams, Christopher Towler, Ping Wang, Sarah Williams, Ji-Hu Zhang, Matthew J. LaMarche

    Vydáno 2016
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