檢索結果 - Matthias Drosten

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  1. 1
    Targeting the MAPK Pathway in KRAS-Driven Tumors

    Targeting the MAPK Pathway in KRAS-Driven Tumors 由 Matthias Drosten, Mariano Barbacid

    出版 2020
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  2. 2
    Targeting <i>KRAS</i> mutant lung cancer: light at the end of the tunnel

    Targeting <i>KRAS</i> mutant lung cancer: light at the end of the tunnel 由 Matthias Drosten, Mariano Barbacid

    出版 2021
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  3. 3
    The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer

    The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer 由 Lucía Simón-Carrasco, Gerardo Jiménez, Mariano Barbacid, Matthias Drosten

    出版 2018
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  4. 4
    A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer

    A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer 由 Marta Forés, Lucía Simón-Carrasco, Leiore Ajuria, Núria Samper, Sergio González‐Crespo, Matthias Drosten, Mariano Barbacid, Gerardo Jiménez

    出版 2017
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  5. 5
    Active R-RAS2/TC21 prevents cell cycle arrest and morphological alterations in mouse embryonic fibroblasts lacking RAS proteins

    Active R-RAS2/TC21 prevents cell cycle arrest and morphological alterations in mouse embryonic fibroblasts lacking RAS proteins 由 Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Matthias Drosten, Eugenio Santos, Mariano Barbacid, Balbino Alarcón, Xosé R. Bustelo

    出版 2025
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  6. 6
    Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma

    Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma 由 Lucía Simón-Carrasco, Osvaldo Graña‐Castro, Marina Salmón, Harrys K.C. Jacob, Alejandro Gutiérrez, Gerardo Jiménez, Matthias Drosten, Mariano Barbacid

    出版 2017
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  7. 7
    Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

    Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival 由 Matthias Drosten, Alma Dhawahir, Eleanor Y. M. Sum, Jelena Urosevic, Carmen G. Lechuga, Luis Miguel Pedrero Esteban, Esther Castellano, Carmen Guerra, Eugenio Santos, Mariano Barbacid

    出版 2010
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  8. 8
    c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling

    c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling 由 Manuel Sanclemente, Sarah Francoz, Laura Esteban-Burgos, emilie Bousquet-Mur, Magdolna Djurec, Pedro P. López‐Casas, Manuel Hidalgo, Carmen Guerra, Matthias Drosten, Mónica Musteanu, Mariano Barbacid

    出版 2018
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  9. 9
    Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild-Type K-Ras

    Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild-Type K-Ras 由 David Matallanas, David Romano, Fahd Al‐Mulla, Eric O’Neill, Waleed Al-Ali, Piero Crespo, Brendan Doyle, Colin Nixon, Owen J. Sansom, Matthias Drosten, Mariano Barbacid, Walter Kölch

    出版 2011
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  10. 10
    Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway

    Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway 由 Matthias Drosten, Eleanor Y. M. Sum, Carmen G. Lechuga, Lucía Simón-Carrasco, Harrys K.C. Jacob, Raquel García-Medina, Sidong Huang, Roderick L. Beijersbergen, René Bernards, Mariano Barbacid

    出版 2014
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  11. 11
    Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties

    Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties 由 Yijun Gao, Matthew T. Chang, Daniel J. McKay, Na Na, Bing Zhou, Rona Yaeger, Neilawattie M. Torres, Keven Muniz, Matthias Drosten, Mariano Barbacid, Giordano Caponigro, Darrin D. Stuart, Henrik Moebitz, David B. Solit, Omar Abdel‐Wahab, Barry S. Taylor, Zhan Yao, Neal Rosen

    出版 2018
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  12. 12
    Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS

    Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS 由 Zhan Yao, Rona Yaeger, Vanessa Rodrik-Outmezguine, Anthony Tao, Neilawattie M. Torres, Matthew T. Chang, Matthias Drosten, HuiYong Zhao, Franco Cecchi, Todd Hembrough, Judith Michels, Hervé Baumert, Linde A. Miles, Naomi Campbell, Elisa de Stanchina, David B. Solit, Mariano Barbacid, Barry S. Taylor, Neal Rosen

    出版 2017
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  13. 13
    Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas

    Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas 由 Marina Salmón, Ruth Álvarez, Coral Fustero‐Torre, Oksana Brehey, Carmen G. Lechuga, Manuel Sanclemente, Fernando Fernández-García, Alejandra López-García, María Carmen Martín-Guijarro, Sandra Rodríguez, Emily Bousquet-Mur, Lucía Morales-Cacho, Francisca Mulero, Fátima Al‐Shahrour, Lola Martínez, Orlando Domı́nguez, Eduardo Caleiras, Sagrario Ortega, Carmen Guerra, Mónica Musteanu, Matthias Drosten, Mariano Barbacid

    出版 2023
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  14. 14
    Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

    Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF 由 Maria Blasco, Carolina Navas, Guillermo Martín‐Serrano, Osvaldo Graña‐Castro, Carmen G. Lechuga, Laura Martín-Díaz, Magdolna Djurec, Jing Li, Lucía Morales-Cacho, Laura Esteban-Burgos, Javier Perales-Patón, emilie Bousquet-Mur, Eva Castellano, Harrys K.C. Jacob, Lavinia Cabras, Mónica Musteanu, Matthias Drosten, Sagrario Ortega, Francisca Mulero, Bruno Sáinz, Nelson Dusetti, Juan Iovanna, Francisco Sánchez‐Bueno, Manuel Hidalgo, Hossein Khiabanian, Raúl Rabadán, Fátima Al‐Shahrour, Carmen Guerra, Mariano Barbacid

    出版 2019
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  15. 15
    Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer

    Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer 由 Irati Macaya, Marta Román, Connor Welch, Rodrigo Entrialgo‐Cadierno, Marina Salmón, Alba Santos, Iker Feliu, Joanna Kovalski, Inés López, María Rodríguez‐Remírez, Sara Palomino‐Echeverría, Shane M. Lonfgren, Macarena Ferrero, Silvia Calabuig‐Fariñas, Iziar A. Ludwig, David Lara‐Astiaso, Eloísa Jantus‐Lewintre, Elizabeth Guruceaga, Shruthi Narayanan, Mariano Ponz‐Sarvisé, Antonio Pineda‐Lucena, Fernando Lecanda, Davide Ruggero, Purvesh Khatri, Enrique Santamaría, Joaquín Fernández‐Irigoyen, Irene Ferrer, Luis Paz‐Ares, Matthias Drosten, Mariano Barbacid, Ignacio Gil‐Bazo, Silvestre Vicent

    出版 2023
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