檢索結果 - Martin Rowlands
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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity 由 Lindsay Stimson, Martin Rowlands, Yvette Newbatt, Nicola F. Smith, Florence I. Raynaud, Paul A. Rogers, Vassilios Bavetsias, Stephen Gorsuch, Michael Jarman, Andrew J. Bannister, Tony Kouzarides, Edward McDonald, Paul Workman, G. Wynne Aherne
出版 2005Artigo -
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Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response 由 Maruf M. U. Ali, Tina Bagratuni, Emma L. Davenport, Piotr Nowak, M. Cris Silva-Santisteban, Anthea Hardcastle, Craig McAndrews, Martin Rowlands, Gareth J. Morgan, Wynne Aherne, Ian Collins, Faith E. Davies, Laurence H. Pearl
出版 2011Artigo -
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Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766) 由 N. Chessum, Swee Y. Sharp, John Caldwell, Elisa Pasqua, Birgit Wilding, Giampiero Colombano, Ian Collins, Buǧra Özer, Meirion Richards, Martin Rowlands, Mark Stubbs, Rosemary Burke, Craig McAndrew, Paul A. Clarke, Paul Workman, Matthew D. Cheeseman, Keith Jones
出版 2017Artigo -
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Discovery of 4-Amino-1-(7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt) 由 Tatiana McHardy, John Caldwell, Kwai-Ming J. Cheung, Lisa J. Hunter, Kevin Taylor, Martin Rowlands, Ruth Ruddle, Alan T. Henley, Alexis de Haven Brandon, Melanie Valenti, Thomas G. Davies, Lynsey Fazal, Lisa C. A. Seavers, Florence I. Raynaud, Suzanne A. Eccles, G. Wynne Aherne, Michelle D. Garrett, Ian Collins
出版 2010Artigo -
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<i>In vitro</i> Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors 由 Swee Y. Sharp, Kathy Boxall, Martin Rowlands, Chrisostomos Prodromou, S. Mark Roe, Alison Maloney, Marissa Powers, Paul A. Clarke, Gary Box, Sharon Sanderson, Lisa Patterson, Thomas P. Matthews, Kwai-Ming J. Cheung, Karen Ball, Angela Hayes, Florence I. Raynaud, Richard Marais, Laurence H. Pearl, Sue Eccles, Wynne Aherne, Edward McDonald, Paul Workman
出版 2007Artigo -
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Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen 由 Matthew D. Cheeseman, N. Chessum, Carl S. Rye, Elisa Pasqua, Michael Tucker, Birgit Wilding, Lindsay E. Evans, Susan Lepri, Meirion Richards, Swee Y. Sharp, Salyha Ali, Martin Rowlands, Lisa O’Fee, Asadh Miah, Angela Hayes, Alan T. Henley, Marissa Powers, Robert te Poele, Emmanuel de Billy, Loredana Pellegrino, Florence I. Raynaud, Rosemary Burke, Rob L. M. van Montfort, Suzanne A. Eccles, Paul Workman, Keith Jones
出版 2016Artigo -
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NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis 由 Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Swee Y. Sharp, Gary Box, Melanie Valenti, Lisa Patterson, Alexis de Haven Brandon, Sharon Gowan, Frances Boxall, Wynne Aherne, Martin Rowlands, Angela Hayes, Vanessa Martins, Frederique Urban, Kathy Boxall, Chrisostomos Prodromou, Laurence H. Pearl, Karen James, Thomas P. Matthews, Kwai-Ming J. Cheung, Andrew Kalusa, Keith Jones, Edward McDonald, Xavier Barril, Paul A. Brough, Julie E. Cansfield, Brian Dymock, Martin J. Drysdale, Harry Finch, Rob Howes, Roderick E. Hubbard, Alan Surgenor, Paul Webb, Mike Wood, Lisa Wright, Paul Workman
出版 2008Artigo
相關主題
Biology
Biochemistry
Chemistry
Gene
Heat shock protein
Internal medicine
Medicine
Bioavailability
Cell biology
Cell growth
Computational biology
Genetics
Molecular biology
Pharmacology
Protein kinase A
Protein kinase B
Small molecule
Stereochemistry
Surgery
Transcription factor
Acetylation
Acetyltransferase
Amino acid
Anesthesia
Angiogenesis
Anticoagulant
Apoptosis
Atrial fibrillation
Autophosphorylation
Biophysics