Výsledky vyhledávání - Martin Empting

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  1. 1
    Targeting the <i>Pseudomonas</i> quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers

    Targeting the <i>Pseudomonas</i> quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers Autor Christian Schütz, Martin Empting

    Vydáno 2018
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  2. 2
    Single-domain antibodies for biomedical applications

    Single-domain antibodies for biomedical applications Autor Simon Krah, Christian Schröter, Stefan Zielonka, Martin Empting, Bernhard Valldorf, Harald Kolmar

    Vydáno 2015
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  3. 3
    Structural insights and biomedical potential of IgNAR scaffolds from sharks

    Structural insights and biomedical potential of IgNAR scaffolds from sharks Autor Stefan Zielonka, Martin Empting, Julius Grzeschik, Doreen Könning, Caroline J. Barelle, Harald Kolmar

    Vydáno 2014
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  4. 4
    Design and Synthesis of a Library of Lead-Like 2,4-Bisheterocyclic Substituted Thiophenes as Selective Dyrk/Clk Inhibitors

    Design and Synthesis of a Library of Lead-Like 2,4-Bisheterocyclic Substituted Thiophenes as Selective Dyrk/Clk Inhibitors Autor C. Schmitt, Dagmar Kail, Marica Mariano, Martin Empting, Nadja Weber, Tamara Paul, Rolf W. Hartmann, Matthias Engel

    Vydáno 2014
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  5. 5
    In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment

    In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment Autor Giuseppe Allegretta, Christine K. Maurer, Jens Eberhard, Damien Maura, Rolf W. Hartmann, Laurence G. Rahme, Martin Empting

    Vydáno 2017
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  6. 6
    Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa

    Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa Autor J. Henning Sahner, Martin Empting, Ahmed A. M. Kamal, Elisabeth Weidel, Matthias F. Groh, Carsten Börger, Rolf W. Hartmann

    Vydáno 2015
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  7. 7
    Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling

    Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling Autor Monika I. Hollenhorst, Innokentij Jurastow, Rajender Nandigama, Silke Appenzeller, Lei Li, Jörg Vogel, Stephanie Wiederhold, Mike Althaus, Martin Empting, Janine Altmüller, Anna K. H. Hirsch, Veit Flockerzi, Brendan J. Canning, Antoine‐Emmanuel Saliba, Gabriela Krasteva‐Christ

    Vydáno 2019
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  8. 8
    Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of <i>P. aeruginosa</i> Biofilm Infections

    Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of <i>P. aeruginosa</i> Biofi... Autor Duy‐Khiet Ho, Xabier Murgia, Chiara Rossi, Rebekka Christmann, Antonio G. Hüfner de Mello Martins, Marcus Koch, Anastasia Andreas, Jennifer Herrmann, Rolf Müller, Martin Empting, Rolf W. Hartmann, Didier Desmaële, Brigitta Loretz, Patrick Couvreur, Claus‐Michael Lehr

    Vydáno 2020
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  9. 9
    Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof‐of‐Principle

    Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof‐of‐Principle Autor Mostafa M. Hamed, Ahmed S. Abdelsamie, Katharina Rox, Christian Schütz, Andreas M. Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce‐Rodríguez, José Manuel Borrero‐de Acuña, Dieter Jahn, Jessica Rademacher, Felix C. Ringshausen, Nina Cramer, Burkhard Tümmler, Anna K. H. Hirsch, Rolf W. Hartmann, Martin Empting

    Vydáno 2023
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  10. 10
    A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate <i>Pseudomonas aeruginosa</i> Biofilms

    A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate <i>Pseudomonas aeruginosa</i> Biofilms Autor Christian Schütz, Duy‐Khiet Ho, Mostafa M. Hamed, Ahmed S. Abdelsamie, Teresa Röhrig, Christian Herr, Andreas M. Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbürger, Marius Wirth, Carsten Börger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus C. Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna K. H. Hirsch, Rolf W. Hartmann, Claus‐Michael Lehr, Martin Empting

    Vydáno 2021
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  11. 11
    Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor

    Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor Autor Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek‐Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-François Éléouët, Marie‐Anne Rameix‐Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann

    Vydáno 2024
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  12. 12
    Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

    Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality Autor Chelsea E. Cunningham, Frederick S. Vizeacoumar, Yue Zhang, Liliia Kyrylenko, Simon Both, Vincent Maranda, He Dong, Jared D.W. Price, Peng Gao, Konrad Wagner, Yingwen Wu, Mary Lazell-Wright, Ashtalakshmi Ganapathysamy, Rithik Hari, Kalpana K. Bhanumathy, Connor Denomy, Anjali Saxena, Jeff P Vizeacoumar, Alain Morejon Morales, Faizaan Khan, Shayla R. Mosley, A. Chen, Tetiana Katrii, Ben G. E. Zoller, Karthic Rajamanickam, Prachi Walke, Lihui Gong, Hardikkumar Patel, Hussain Elhasasna, Renuka Dahiya, Omar Abuhussein, Anton E. Dmitriev, Tanya Freywald, Érika Prando Munhoz, Eytan Ruppin, Joo Sang Lee, Katharina Rox, Martin Köebel, Laura Hopkins, Cheng‐Han Lee, Sunil Yadav, Gilles Gasparoni, Walter Jörn, Anand Krishnan, Raju Datla, Behzad M. Toosi, Kristi Baker, Jalna Meens, David W. Cescon, Laurie Ailles, Scot C. Leary, Yuliang Wu, Martin Empting, Alexandra K. Kiemer, Andrew Freywald, Franco J. Vizeacoumar

    Vydáno 2025
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