Resultats de la cerca - Lyubomir T. Vassilev

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  1. 1
    Small-Molecule Antagonists of p53-MDM2 Binding: Research Tools and Potential Therapeutics

    Small-Molecule Antagonists of p53-MDM2 Binding: Research Tools and Potential Therapeutics per Lyubomir T. Vassilev

    Publicat 2004
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  2. 2
    Cell Cycle Synchronization at the G<sub>2</sub>/M Phase Border by Reversible Inhibition of CDK1

    Cell Cycle Synchronization at the G<sub>2</sub>/M Phase Border by Reversible Inhibition of CDK1 per Lyubomir T. Vassilev

    Publicat 2006
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  3. 3
    Targeting the p53–MDM2 interaction to treat cancer

    Targeting the p53–MDM2 interaction to treat cancer per Christian Klein, Lyubomir T. Vassilev

    Publicat 2004
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  4. 4
    An initiation zone of chromosomal DNA replication located upstream of the c-myc gene in proliferating HeLa cells.

    An initiation zone of chromosomal DNA replication located upstream of the c-myc gene in proliferating HeLa cells. per Lyubomir T. Vassilev, Edward M. Johnson

    Publicat 1990
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  5. 5
    Mapping initiation sites of DNA replication<i>in vivo</i>using polymerase chain reaction amplification of nascent strand segments

    Mapping initiation sites of DNA replication<i>in vivo</i>using polymerase chain reaction amplification of nascent strand segments per Lyubomir T. Vassilev, Edward M. Johnson

    Publicat 1989
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  6. 6
    p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation

    p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation per Mingxuan Xia, Dejan Knezevic, Lyubomir T. Vassilev

    Publicat 2010
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  7. 7
    Mapping an origin of DNA replication at a single-copy locus in exponentially proliferating mammalian cells.

    Mapping an origin of DNA replication at a single-copy locus in exponentially proliferating mammalian cells. per Lyubomir T. Vassilev, William C. Burhans, Melvin L. DePamphilis

    Publicat 1990
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  8. 8
    Selective ATM inhibition augments radiation-induced inflammatory signaling and cancer cell death

    Selective ATM inhibition augments radiation-induced inflammatory signaling and cancer cell death per Li-Ya Chiu, Qing Sun, Frank T. Zenke, Andree Blaukat, Lyubomir T. Vassilev

    Publicat 2023
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  9. 9
    Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity

    Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity per Zakir Ullah, Matthew J. Kohn, Rieko Yagi, Lyubomir T. Vassilev, Melvin L. DePamphilis

    Publicat 2008
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  10. 10
    Induction of p53-Dependent Senescence by the MDM2 Antagonist Nutlin-3a in Mouse Cells of Fibroblast Origin

    Induction of p53-Dependent Senescence by the MDM2 Antagonist Nutlin-3a in Mouse Cells of Fibroblast Origin per Alejo Efeyan, Ana Ortega-Molina, Susana Velasco-Miguel, Daniel Herranz, Lyubomir T. Vassilev, Manuel Serrano

    Publicat 2007
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  11. 11
    Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregation.

    Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregation. per William C. Burhans, Lyubomir T. Vassilev, Jiarui Wu, José M. Sogo, Ferez S. Nallaseth, Melvin L. DePamphilis

    Publicat 1991
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  12. 12
    Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

    Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1 per Lyubomir T. Vassilev, Christian Tovar, Shaoqing Chen, Dejan Knezevic, Xiaolan Zhao, Hongmao Sun, David Heimbrook, Li Chen

    Publicat 2006
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  13. 13
    MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines

    MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines per Hege O. Ohnstad, Erik B. Paulsen, Paul Noordhuis, Marianne Berg, Ragnhild A. Lothe, Lyubomir T. Vassilev, Ola Myklebost

    Publicat 2011
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  14. 14
    Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814

    Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814 per Qing Sun, Yige Guo, Xiaohong Liu, Frank Czauderna, Michael I. Carr, Frank T. Zenke, Andree Blaukat, Lyubomir T. Vassilev

    Publicat 2019
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  15. 15
    Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5

    Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5 per Bing Z. Carter, Duncan H. Mak, Wendy Schober, Martin Dietrich, Clemencia Pinilla, Lyubomir T. Vassilev, John C. Reed, Michael Andreeff

    Publicat 2008
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  16. 16
    Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML

    Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML per Bing Z. Carter, Duncan H. Mak, Wendy Schober, Erich Koller, Clemencia Pinilla, Lyubomir T. Vassilev, John C. Reed, Michael Andreeff

    Publicat 2009
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  17. 17
    Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis

    Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis per Thelma Thompson, Christian Tovar, Hong Yang, Daisy Carvajal, Binh Thanh Vu, Qunli Xu, Geoffrey M. Wahl, David Heimbrook, Lyubomir T. Vassilev

    Publicat 2004
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  18. 18
    Depletion of Mutant p53 and Cytotoxicity of Histone Deacetylase Inhibitors

    Depletion of Mutant p53 and Cytotoxicity of Histone Deacetylase Inhibitors per Mikhail V. Blagosklonny, Shana Y. Trostel, Ganesh Kayastha, Zoya N. Demidenko, Lyubomir T. Vassilev, Larisa Y. Romanova, Susan E. Bates, Tito Fojo

    Publicat 2005
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  19. 19
    A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies

    A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies per Astrid Zimmermann, Frank T. Zenke, Li-Ya Chiu, Heike Dahmen, Ulrich Pehl, Thomas Fuchß, Thomas Grombacher, Beatrix Blume, Lyubomir T. Vassilev, Andree Blaukat

    Publicat 2022
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  20. 20
    Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

    Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models per Frank T. Zenke, Astrid Zimmermann, Christian Sirrenberg, Heike Dahmen, Vladimir Kirkin, Ulrich Pehl, Thomas Grombacher, Claudia Wilm, Thomas Fuchß, Christiane Amendt, Lyubomir T. Vassilev, Andree Blaukat

    Publicat 2020
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